In the ob/ob mice, we observed a significant upregulation of the mRNA expression of Ccl2 (a chemokine that regulates migration and infiltration of monocytes/macrophages), Adgre1 (a marker reflecting the total number of mature macrophages), Itgax (a marker of dendritic cells), and Cd68 (a marker of monocytes/macrophages), while a reduction of the expression of Cd163 (a marker of anti-inflammatory monocyte/macrophages), barely failed to attain statistical significance ( P = 0.060) in ob/ob mice compared to db/db and lean mice (Fig. 2 c).
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“barely failed to attain statistical significance”
Sighted at
p=0.067
In the literature
Multiple progression contributed to poorer OS though barely failed to attain statistical significance (HR, 3.26; 95 % CI, 0.94–11.28; p = 0.062).
AVN barely failed to attain statistical significance.
Moreover, the correlation between changes in arteriolar blood flow and axial length barely failed to attain statistical significance.
Additionally, in the resistance training group, a positive correlation between changes in serum levels of insulin-like growth factor 1 (IGF-1) and P3 amplitudes (measured during switching condition) and a negative correlation between serum levels of tumor necrosis factor-alpha and accuracy rates in the switching condition were observed, which both barely failed to attain statistical significance [ 191 ].