“at the limit of significance”

Although this difference is rather small and at the limit of significance, it is in agreement with the FcRn SPR analysis data obtained for this sample and suggests that the 20% oxMet428 content may result in improved FcRn affinity and PK properties.

In multivariate analysis, the occurrence of toxicities was associated with OS, but BMI was at the limit of significance.

It should be noted, however, that subjective well-being shows higher levels of positive affect (at the limit of significance) and in perception of overall happiness, but not of negative affect.

Stretched GCM was also significantly stiffer in group 2 (8.8 ± 4.1 kPa) than in group 1 (2.9 ± 0.7 kPa, p = 0.0001) and group 3 (5.0 ± 0.9 kPa, p = 0.05), although the latter comparison was at the limit of significance.

Indeed, we were at the limit of significance for the AGP39 dataset and significant for the pig2 dataset.

But sAA and testosterone remained at the limit of significance ( Table 1 ).

However, data suggested potential protective effect: cases/controls, OR = 0.8295, CI 95% [0.4229, 1.6271], 0.0521, the result being at the limit of significance.

Given that this result is at the limit of significance, this result should be considered alongside the other studies described here which more comprehensively contrast with this finding.

Although the presence of socio-demographic factors (i.e., gender and educational level) is consistent with the literature ( Hamam et al., 2020 ), the lack of control of educational level (which was at the limit of significance) represents a non-negligible limitation.

In addition, despite the fact that total dietary fiber intake was at the limit of significance, the evaluation of the consumption of cereal products, based on the Canadian Food Guide recommended intakes for grain products (Canadian-Healthy Eating Index, C-HEI) was significantly lower in cases in comparison to controls (corrected p-value = 0.052 and 0.013, respectively). 4.2 Serum metabolomes in the NuAge sub-cohort Given the high diversity of metabolites present over a wide concentration range in biological samples, proper MetS evaluation requires a broad metabolome coverage.

In the subgroup of studies that found weak effects on rumination the reduction in depression scores was at the limit of significance ( k = 6; g = −0.29; 95% CI: −0.58, 0.00; I 2 = 44%), although there was (non-significant) heterogeneity with two studies showing a medium and strong effect, respectively.

BMI was also positively correlated to CYP1A2 activity in our study, but at the limit of significance.

We found an association of outdoor levels of heavy oil combustion with two of the outcomes, but chance could not be excluded due to the p -values at the limit of significance and the lack of association with indoor levels or with Ni and V, the main elements defining this source.

The adjusted HRs for males compared to females were significant in Austria (1.4, 95% CI 1.1–1.9) and Denmark (1.6, 95% CI 1.0–2.7), at the limit of significance in Germany-Dusseldorf (1.4, 95% CI 0.9–2.0) and not significant in Sweden (1.0, 95% CI 0.7–1.3) ( Table 3 and Fig 4 ).

Association between PM 2.5 , BC and NO 2 and stroke Results of the multivariable logistic regression models showed a significant association between stroke and PM 2.5, while associations with NO 2 and BC were at the limit of significance (Table 3 ).

Other specific enrichments found in Chia’s secondary screening were detected at the limit of significance at FDR 0.05 by HTS-Net, such as ‘oligodendrocyte development’, ‘cellular response to stimulus’ and processes related to ‘negative regulation of transcription’ and ‘negative regulation of translational initiation in response to stress’.

However, in contrast to the EMCV IRES, cleavage around the initiation codon in the FMDV IRES from C351 of eIF4A was very weak, at the limit of significance ( Figure 5 E).

However, the same analyses in the case of PEA, retinol and beta-carotene resulted underpowered, at the limit of significance in case of BMI and FFA, and had sufficient power in the case of AEA, 2AG, SAFA and PA/LA.

The gender difference decrease was about 63 % in the 16–18-year-olds and 41 % in the 19–12-year-olds, and was at the limit of significance after the adjustment.

The difference between PPCM patients with and without LGE with regards to LV GLS rate was at the limit of significance probably due to small number of patients studied and should be evaluated in further research.

Only a small increase in IL-1β secretion at the limit of significance was observed, and hence without signs of a potent inflammatory cascade in the tissues.

The group of second-year residents presented greater concordance, although still at an intermediate level (0.566), with a p -value of 0.064, which was at the limit of significance.

, at the limit of significance) relative loss of Fe was detected.

Furthermore, the difference in FeNO before and after EC in the asthmatics was correlated with the corresponding differences in respiratory resistance at 5 and 20 Hz (R5Hz and R20Hz) at the limit of significance, where the number 0.000 was the lowest limit of the 95% of the confidence intervals (Table 1 ).

Patients with CSF flow at the CCJ before surgery (0–2 points at CSF flow score, Table 1 ) tend to have a higher probability (OR = 4.75, IC 95% 0.95–23.85, at the limit of significance) of post-surgical improvement than patients with absent CSF flow at the CCJ (3 points at the CSF flow score, Table 1 ).