1e ), with 19 showing significant differences in methylation between first treatment and relapse, and a further three approaching significance ( P FDR < 0.085) (Table 1 ).
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“approaching significance”
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FWF spatial variance in NAWM decreased with SDMT score in 16 ROIs in MS patients, including the genu and body of corpus callosum, corticospinal tract (cst) right and left (approaching significance for the first one), the sagittal stratum right and left, the superior cerebellar peduncle right, the alic‐R, the superior longitudinal fasciculus (slf) right, approaching significance for slf‐left (see Table S2 and Figure 6 ). 4 DISCUSSION This study quantified cerebral FWF in clinically stable RRMS and investigated its relationship with lesion burden and information processing speed.
However, when compared with the control group, the intervention group only had a significantly higher mean change in potassium from baseline to 6 weeks, despite protein and fibre approaching significance at this time point indicating positive trends.
Effect estimates are reported as hazard ratios (HR) with associated 95% confidence intervals (CIs) and p -values, with two-sided p -values less than < 0.05 considered significant and p -values between 0.05 and 0.10 considered approaching significance.
FIGURE S2 Analysis of different habenulae subnuclei reveals expansion of subnuclei, some approaching significance.
It is interesting to note that the P value approaching significance is driven by 1 subject in the standard treatment group who became undetectable at 48 weeks.
Based on our current data, we would need at least 19 mice per group to detect the small effect of the chr10 A/J variants in the traits approaching significance at 5 months of age (somatic instability in the liver and intranuclear inclusions), perhaps fewer at a more advanced age where each phenotype is more robustly detected (Wheeler et al. 2002 ).
An improvement was reported for 60% and 77%of the patients in MS and ACE scores respectively, with this improvement approaching significance.
detected at enrollment week, within the model; however, some variables are approaching significance ( Supplementary Table 1 ), and there was a systematic directionality in the effect of minimum temperature, across the lagged times.
For the monolingual preschoolers, the results were also non-significant [ t (12) = −2.12, p = 0.055], however, as the p-value was 0.055 and was approaching significance, this may indicate that there is potentially an interference effect between trial types for monolingual preschoolers and should be tested further with a larger sample.
(2009) reported such relationship for only 1 comparison out of 4, a careful examination of their figure S4 A , suggests that at least one other comparison may be approaching significance, demonstrating the same pattern we observed in this study: highly expressed genes are strongly compensated for the deficiency, perhaps with a hint of a nonmonotonic relationship (see also fig.
For liver function-related indicators, AST levels in the S2 group decreased to 344.16 U/L ( p = 0.06), approaching significance), while ALT levels were significantly reduced in all MCE-supplemented groups, with the lowest level observed in the S2 group ( p < 0.01).
In the subgroup of low risk of bias studies (n = 4), effect sizes remained in favour of CB, were smaller and more precise, and were either approaching significance (n = 4) or significant (n = 1).
These showed a similar relationship of these parameters to outcome, albeit less marked, with the mean R2* on air being significant (and O 2 approaching significance). 3.2.3.
PIK3CD is the gene that encodes for the primary target of RV1001 (PI3Kδ) and was increased in good responders at baseline with approaching significance.
Interestingly, there were no significant differences in POs characteristics between groups, although some findings were approaching significance. 5 In the pre-crime phase, several differences were observed between sexual robbery and sexual burglary.
Although your study is still very meaningful with approaching significance, could you please comment on why this may be the case for your specific study and how your approach could be further improved?
Statistical significance was defined as p < 0.05, but findings approaching significance were reported for the sake of completeness. 3.
Additionally, the association between three to four other AH claims and declined admission was approaching significance level.
Index Generation: Molecules that achieved statistical significance in the multivariate analysis, as well as those with results approaching significance, were selected.
When stratifying our cohort by physician involvement, videos with physicians exhibited significantly higher reliability and quality scores, with an overall DISCERN score nearly approaching significance.
While the improvements observed in the frontal and transverse planes were statistically significant or approaching significance, changes in the sagittal plane were less pronounced and did not reach significance within the study period.
The interaction of ND and age was not statistically significant, with an effect approaching significance.
However, they fail to identify and discuss some clear trends that are approaching significance.
Our cross-sectional findings remain largely unaffected, although one variable (maladaptive coping) which was previously approaching significance has now reached statistical significance.