“approaching significance”

Despite that a decreased risk of PE was found after exposure to the increased concentrations of PM 10 during the first trimester with approaching significance (aOR = 0.938, 95% CI: 0.875–1.006), exposure to PM 2.5 and PM 10 during other periods did not show any risk of GH and PE.

E‐R for safety revealed no significant relationship for grade 3/4 neutropenia; however, a positive E‐R relationship was observed for grade 3/4 thrombocytopenia and imetelstat cycle 1 exposure (statistically significant for C max and approaching significance for AUC; Figure 3 ). 20 Importantly, no significant E‐R was seen for safety events considered clinical consequences of these cytopenias, in terms of any grade or grade 3/4 infections or bleeding events (Figure 3 ).

5a ) the SR values of S-T and T-S are 2.02 (significant) and 1.91 (approaching significance), respectively.

However, some studies done previously have shown a significant association with age and duration of DM.[ 27 , 28 , 29 ] The current study also had higher age and duration of DM in the MSD group, which was approaching significance.

In a multivariable model adjusting for the presence of genetic syndrome and single-ventricle physiology, the adjusted HR of 1.44 for PMP (95% CI: 0.995–2.90; P = 0.054) demonstrated a possible independent association with increased mortality approaching significance.

In patients with a SOFA score < 1, ePVS was significantly associated with 30-day mortality (HR = 1.12, 95%CI: 1.04–1.21), and although the risk of death for patients with ePVS levels ≥5.79 was approaching significance (HR = 1.29, 95% CI: 0.95–1.74), it remained noteworthy.

Differences in the mean duration of contact with the port between the sit and stand-stare dogs were approaching significance ( Figure 3 ).

In the same samples, of the 22 phenotypic genes in the analysis geneset, nine did not show coexpression with either Ar or Esr2 , three had coexpression approaching significance with Esr2 and 10 had strong coexpression with Esr2 , Ar or both.

resulted in the pooled effect estimate (of the two remaining studies) approaching significance but leave-one-out analysis did not result in any p estimates dropping below 0.05 and all 95%CIs overlapped the null.

For the multivariate binary logistic regression model, variables were selected based on whether they demonstrated a significant association (p < 0.05) or were approaching significance in the univariate analyses to investigate their combined relationship with health literacy (Table 1 ).

If these were removed, the correlation was no longer approaching significance (see Fig. 2 for scatterplots).

However, in a secondary analysis that included all ETEC-positive MSD events regardless of copathogens, ETVAX prevented nearly half of ETEC-positive diarrhoea events, approaching significance.

It also seems unlikely that a trial of this size would have the power to detect a change, and thus, the trial approaching significance did not come as a surprise.

Participants in the experimental Arm B (face-to-face and Internet lesson) showed an increase in favorable attitudes toward hearing conservation approaching significance at 3 months (Table 3 ).

Based on the univariate analysis, factors that had a relation to serum total IgE that was statistically significant or approaching significance were included in the multivariate analysis.

Ethnic associations with stroke diagnoses were more variable: Compared to White patients, we found excess hazards for South Asian patients for ischaemic stroke (HR 1.29 (1.03–1.62)) and excess hazards approaching significance for Black patients for both ischaemic stroke (1.24 (0.97–1.58)) and intracerebral haemorrhage (1.44 (0.97–2.12)).

Finally, while the sample size provided adequate power for most statistical analyses, larger samples would allow for more sophisticated multivariate modelling and enhance the stability of results, particularly for findings approaching significance thresholds.

While approaching significance, our findings do not clearly appear to support mailing an advance letter to improve the likelihood of reaching a participant.

Repeated measures ANOVAs showed significant differences by time for 3 (PedsQL Total score, P =0.035; PedsQL Social Functioning, P =0.033; PSS, P =0.008) of 8 secondary outcomes, with an additional outcome (PedsQL Emotional Functioning: P =0.055) approaching significance ( Table 5 ).

This study was limited by its smaller sample size, but given prior work documenting the importance of this factor and the fact that the association was approaching significance, this may merit more in‐depth investigation.

For the most parsimonious model (leave-one-out analysis at the distance of one standard error), 6 of 9 genes were significantly different between SF-295 and A549, with one not profiled and one approaching significance (Fig. 3 A).

irrelevant) mixed-model ANOVA was performed that yielded a main effect of Stimulus Type, F (1,50) = 5.60, p = 0.02, η 2 = 0.02, and a Condition × Stimulus Type interaction, F (1,50) = 3.78, p = 0.06, η 2 = 0.01, approaching significance.

However, all-cause death was reduced in women relative to men by half, with a P value approaching significance.

WR (POSwr: β = 0.10, p = 0.065) and CB (POScb: β = 0.11, p = 0.054) had moderate positive coefficients approaching significance.

Although approaching significance at the eight-week follow-up assessment, there were no significant changes in self-efficacy between the three data collection points.