Barely Significant
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“approaching significance”

2,641 sentences · 2,641 papers · 3,385 search hits before verification · confirmed specimen

Sighted at

p=0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

approaching significancep = 0.051.0× alphagold
Significant associations between nutrition knowledge and the dietary intake of total carotenoids and α-carotene were observed (r = 0.17, p = 0.03, and r = 0.20; p = 0.01, respectively), with the exception of β-carotene and lutein/zeaxanthin, which were approaching significance (r = 0.15, p = 0.05, and r = 0.14; p = 0.06, respectively).
approaching significancep = 0.0501.0× alphagold
Subgroup-specific estimates revealed a modest benefit for biological augmentation (MD = 3.65) versus a non-significant deficit for structural (MD = −2.53), with the interaction test approaching significance (Q = 3.83, df = 1, p = 0.050), indicating potential superiority of biological approaches at this interval, though tempered by high within-group variability.
approaching significancep = 0.0501.0× alphagold
In a sub-analysis of patients with portal vein invasion, OS was 6.5 months (95% CI = 4.5–8.4) in the sorafenib monotherapy group, versus 11.4 months (95% CI = 7.0–15.9) in the sorafenib + low-dose FP combination therapy group, with the difference approaching significance (HR = 0.493, 95% CI = 0.240–1.014, p = 0.050), suggesting that HAIC has an additional effect on OS in patients with major portal vein invasion.
approaching significancep ≈ 0.051.0× alphagold
Expression and validation of biomarkers To validate biomarker expression patterns, Wilcoxon rank-sum tests revealed that in biomarker set 1, both BID and NDUFB6 were significantly downregulated in COPD and NSCLC with COPD groups compared to controls, while PRDX5 showed no significant difference in COPD (though approaching significance, p ≈ 0.05) but was significantly reduced in NSCLC with COPD ( Figures 9 A and 9B); for biomarker set 2, all five biomarkers exhibited significant differential expression in NSCLC versus controls ( Figure 9 C), whereas in NSCLC with COPD only UQCR11 reached significance with the other four biomarkers approaching the threshold ( p ≈ 0.05) ( Figure 9 D).