Barely Significant
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“approaching significance”

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p=0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

approaching significanceP = .061.2× alphagold
Among the cancers with >100 cases of African genetic ancestry, the PRS for thyroid (OR = 1.21, 95% CI = 1.01-1.47, P = .04), colon (OR = 1.29, 95% CI = 1.08-1.53, P = .005), and prostate (OR = 1.40, 95% CI = 1.24-1.58, P = 3.3 × 10 −8 ) were significantly associated with their respective cancer phenotypes ( Figure 1 , Supplemental Table 5 ), and the PRS for breast cancer was approaching significance (OR = 1.12, 95% CI = 0.99-1.26, P = .06).
approaching significanceP = 0.061.2× alphagold
Another consequence of low sample numbers is that, unlike some published studies with larger patient groups, the NMR metabolites were not significantly different between the mild and moderately severe groups, with only lipid CH 3 approaching significance with a reduction in the moderately severe group ( P = 0.06) compared to the mild group.
approaching significancep = 0.061.2× alphagold
Diagnosis, age at diagnosis, income, employment, state/territory of residence, disability status, and Indigenous status had no effect on rates of rediagnosis, however, residing in Tasmania was approaching significance (coefficient −1.67147, p = 0.06) (the Supplementary Data ).
approaching significanceP = 0.061.2× alphagold
We found similar results when considering day 10 anti-Inaba OSP responses and protection from any degree of diarrhea, with differences in mean values approaching significance for both IgM ( P = 0.06) and IgA ( P = 0.05) ( S2 Fig ).
approaching significanceP = 0.061.2× alphagold
By copy number, the relationship between tetracycline in bone and qnrS was approaching significance ( P = 0.06); positive specimens were found with higher copy number (3.23E −12 copy number/16S rRNA copy number, 1.09E −21 –7.71E −11 ) for qnrS than negative (1.46E −12 copy number/16S rRNA copy number, 7.85E −23 –5.76E −11 ) specimens.
approaching significanceP = 0.061.2× alphagold
Interestingly, the average fold induction of cell death relative to untreated cells was higher in CRISPR than in PARENTAL clones for both the highest dose treatments of dasatinib (5.3 vs 2.6) and ketoconazole (11.7 vs 4.4), with P values approaching significance ( P = 0.06 and P = 0.08, respectively). 3.4 Elimination of FOXL2 c. 402C>G mutation modifies the transcriptomic expression signature of granulosa tumor cells It has been previously described that mutation 402C>G in FOXL2 transcription factor, due to its location in the DNA‐binding domain, affects the expression of several target genes [ 26 ], changing the transcriptomic profile of granulosa cells.