Barely Significant
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“approached significance”

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In the literature

In successfully recanalized BAO patients (TICI ≥2b, n=149), excellent recanalization (TICI 3, n=102) approached significance to increase the odds of a favorable outcome (mRS 0–2) at day 90 (aOR=2.177, 95% CI 0.923 to 5.135) and decreased the odds of all-cause mortality at day 90 (aOR=0.408, 95% CI 0.177 to 0.937).
hBOs infected with JEV isolates shrank in circumference by ~5 to 15% by 11 dpi, although when compared with uninfected organoids, this only approached significance for JEV NSW/22 (Fig. 7D ; Supplementary Fig. 13B, C ). hBOs infected with MVEV TC123130 , IMOJEV and YFV 17D infected hBO did not shrink significantly when compared with uninfected controls, although the MVEV TC123130 data suggested a marginal reduction in circumference (Fig. 7C ; Supplementary Fig. 13C ).
Post hoc pairwise testing showed that α-diversity based on the observed features metric was higher after the MSD than the LSD after adjustment for multiple comparisons (mean difference: 7.0 ASV; 95% CI: 0.2, 14.2; P = 0.057); no other pairwise tests approached significance.
Improvements in right and left stride length during comfortable and fast gait of approximately 0.15 meters were noted, but only approached significance (except left comfortable stride length which was statistically significant) and were unpowered as well with achieved power less than 0.50.
Adjusted, multivariable modelling further revealed that older age at treatment start (HR 0.79 per 10 years, p<0.000) was an independent predictor of treatment persistence, and an EDSS of 3.0–5.5 as compared to an EDSS of zero approached significance as an independent predictor of treatment discontinuation ( Figure 1b ).