Barely Significant
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“an overall trend”

4,872 sentences · 4,872 papers · 34,210 search hits before verification · confirmed specimen

Sighted at

p=0.2

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

10 , 11 , 12 There is an overall trend of microglial hyperreactivity in aged mice. 13 , 14 In humans, dystrophy and degeneration of microglia, which result in deterioration of the defensive and neuroprotective capabilities of the senescent CNS, are implicated in brain aging. 15 In turn, aging is related to low‐grade neuroinflammation, i
Potential microglia-based interventions for stroke.
CNS Neurosci Ther · 2020 · PMC7052807
A third randomized trial with a similar sample size, 37 however, failed to show a statistically significant response in FIQ although there was an overall trend toward improvement (baseline FIQ scores: 64.3 for all groups; FIQ at week 13: 50.66, 48.18, 48.62, and 49.45 for placebo and pregabalin 300, 450, and 600 mg/day, respectively; mean change: −13.66, −16.15, −15.71, and −14.88 for placebo, pregabalin 300, 450, and 600 mg/day, respectively: all P -values >0.2).