“an increasing trend”

The prevalence of serotypes 1, 5 and 7F, included in the 10-valent PCV (PCV10) but not in the PCV7, was low (equal to or under 4% for each serotype); however, when considered all together, these serotypes showed an increasing trend over the study period (p for trend p = 0.003).

In the 15–64 age group, ankle fracture surgery decreased from 8,168 in 2008 to 6,281 in 2022 ( p = 0.004), while in the 65 + age group, there was an increasing trend in ankle fracture surgeries from 2,509 in 2008 to 3,276 in 2022 ( p = 0.003).

Paudyal et al.’s HNC study results exhibited an increasing trend in ADC at each intra-treatment week when compared with pretreatment in the complete response group ( p < 0.003) who received CRT [ 20 ].

Analysis of discharge conditions across the period of observation revealed an increasing trend for infectious diseases (ICD10: A00–B99, p =0.003), respiratory diseases (ICD10: J00–J99: p =0.007), genitourinary system (ICD10: N00-N99, p =0.014), as well as symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified (ICD10: R00-R99, p = 0.013) see Table 3.

Informal help-seeking also showed an increasing trend with longer duration [single event: 12%; intermediate: 23%; extreme: 26%; Omnibus χ 2 (2) = 11.7, p = 0.003].

Smoking prevalence showed an increasing trend with higher HGB levels (Q1: 81.95% vs Q4: 93.06%, P=0.003).

By using stage 1 as a reference, an increasing trend in all-cause mortality is shown in patients with higher stages (stage 2: aHR 1.55, 95% CI 1.17–2.07, P = 0.003; stages 3–4: aHR 2.69, 95% CI 1.92–3.76, P < 0.001), as well as for cardiovascular mortality during a follow-up of 50,895.4 person-years.

Of all screened patients, 16.8% ( N = 3361) were cannabis-positive, rising from 15.4% ( n = 112) in January-June/2016 to 17.6% ( n = 246) in January-June/2024 ( p < 0.001), with an increasing trend ( p = 0.003) among the aged 25-64y group ( n = 11901) from 16.6% in January-June/2016 to 22.4% in January-June/2024, and the highest proportion in < 25y age group ( n = 2935, 23.8%).

The results of the presented study obtained on skeletal muscle showed an increasing trend of Caspase 9 immunoreactivity from 4 up to 8 h after death ( p = 0.004), followed by stable—though slightly decreased—levels up to 24 h; a significant immunoreactivity decrease was observed 72 h after death.

There was an increasing trend for the Lawani index of authors, AAGR = 9.4%, p = .004, as of affiliations, AAGR = 11.2%, p = .002 and of countries, AAGR = 6.8%, p = .002.

RCS results demonstrated a nonlinear dose-response relationship between OSA risk and FI levels, with an increasing trend (P = 0.004).

Segmented regression showed an increasing trend in impact factor for publications during 1972 to 1996 ( β = 0.16, p = 0.004) and a decreasing trend during 1997 to 2023 ( β = −0.048, p = 0.005).

In the Cochran–Armitage test, an increasing trend was observed in the infection rate among close contacts ( P = 0.004).

SPD serum levels were significantly higher in ACPA-positive subjects compared with healthy controls (158.5 ± 132.3 ng/mL vs 61.27 ± 34.11 ng/mL; p < 0.0001) and showed an increasing trend from ND subjects to LSRD patients ( p = 0.004).

The positive effect of time showed an increasing trend of SBP (p=0.004) during time.

Similarly, overall internal fit showed an increasing trend as pixel offset values increased ( p = 0.004).

During the period from 2014 to 2021, the number of hospitalized cases of CD had an increasing trend year by year ( r = 0.876, p = 0.004); meanwhile, there was no significant change in the number of UC inpatients ( r = −0.119, p = 0.780) ( Figure 1 ).

58%, p < 0.001), along with an increasing trend in the proportion of endoscopic therapy (G1-4 groups, 14.9% vs. 25.4% vs. 24.6% vs. 30.9%, p = 0.004).

Patients without diabetes showed an increasing trend with age in plaque rupture ( P =0.004) and lipid‐rich plaque ( P =0.018), whereas patients with diabetes had a high prevalence of these vulnerable features at an early age that remained high across age groups.

The linear-by-linear association test revealed that except rs3104746 ( P = 0.638), the risk allele G of both rs9933638 and rs12443621 showed an increasing trend from light smoking to heavy smoking groups ( P = 0.004 and P < 0.001, respectively, p trend < 0.001, Table 4 ).

However, at the 15 mm section, an increasing trend in LWT from P1 to M2 was evident, with significant differences between molar and premolar regions ( P = 0.004).

Six months after surgery, BOP had a decreasing trend in the PRF and CGF groups ( P = 0.003 and P = 0.043), with an increasing trend in the control group ( P = 0.004) ( Table 3 ).

ALFF of right BA39 was positively correlated with age and showed an increasing trend in deaf group with age ( r = 0.574, p = 0.004).

It shows an increasing trend ( p -value = 0.004) between the first and fourth outbreaks, followed by a downward curvilinear trend ( p -value = 0.03) (Supplementary Table 1) during the fifth wave.

jejuni isolates to (fluoro)quinolones showed an increasing trend in samples collected from chickens between 1985 and 2023, with an increase of 11.9 % for CIP ( p = 0.004) and 16.1 % for NAL ( p = 0.027).