“an increasing trend”

With respect to the 10-year trend by region, only “unspecified” showed a repeating pattern of statistically significant increase and decrease up to 2014, followed by an increasing trend starting from 2015 ( P = 0.002).

In terms of tissue functionality, we observed an increasing trend in contraction amplitude, reflecting the magnitude of contraction, in cmBMTs with time, with a striking increase between day 2 and day 14 ( p = 0.0024) (Fig. 5K ).

Moreover, an increasing trend toward liver steatosis severity was observed in patients with BMI ≥ 25 kg/m 2 (Cochran Armitage trend test = 3; p = 0.0027).

An increasing trend in the prevalence of NCDs was witnessed with the increasing age of subject (Spearman correlation, r=0.9643; P =0.0028) ( Fig. 2 ).

A decreasing trend was observed for KC ( P =0.009) and an increasing trend for BK ( P =0.003) and FED ( P =0.001).

The ratio of total child mortality among boys to girls ranged from 0.94 to 1.38 and showed an increasing trend from 1983 to 2012 (Kendall τ=0.38, p =0.003).

The Spearman’s correlation test for association between annual PTH rates and time (year) performed for the adult age group showed a statistically significant, mild to strongly positive correlation, indicating an increasing trend of adult PTH rates over time (year) (Rs = 0.64 [95% CI: 0.28 to 0.84], P = 0.003).

NHW had an increasing trend of prevalence of obesity ( P = 0.003), and NHB consistently had a higher prevalence than NHW.

Paudyal et al.’s HNC study results exhibited an increasing trend in ADC at each intra-treatment week when compared with pretreatment in the complete response group ( p < 0.003) who received CRT [ 20 ].

Trend and Subgroup Analysis of the Non-First-Line Antihypertensive Drugs Use According to Table 4 , the overall proportion of non-first-line antihypertensive prescriptions was 2.53%, showing an increasing trend (APC=27.69%, P =0.003).

ADC and D showed an increasing trend at each intra‐TX week when compared with pre‐TX in CR group ( P < 0.003).

The prevalence of serotypes 1, 5 and 7F, included in the 10-valent PCV (PCV10) but not in the PCV7, was low (equal to or under 4% for each serotype); however, when considered all together, these serotypes showed an increasing trend over the study period (p for trend p = 0.003).

Analysis of discharge conditions across the period of observation revealed an increasing trend for infectious diseases (ICD10: A00–B99, p =0.003), respiratory diseases (ICD10: J00–J99: p =0.007), genitourinary system (ICD10: N00-N99, p =0.014), as well as symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified (ICD10: R00-R99, p = 0.013) see Table 3.

However, the proportion of MDSCs among total urinary cells significantly decreased in the non-recurrence group, whereas it did not decrease in the recurrence group and instead showed an increasing trend ( p = 0.003) (Fig. 3 ).

There was also an increasing trend of RANTES expression in CHIKV-infected patients with significant difference on day 3–4 compared to healthy control ( P = 0.003) (Fig. 4 ).

By using stage 1 as a reference, an increasing trend in all-cause mortality is shown in patients with higher stages (stage 2: aHR 1.55, 95% CI 1.17–2.07, P = 0.003; stages 3–4: aHR 2.69, 95% CI 1.92–3.76, P < 0.001), as well as for cardiovascular mortality during a follow-up of 50,895.4 person-years.

Wear score showed an increasing trend from T 0 to T 1 ( P = 0.003, P = 0.004), and no difference was found between T 1 to T 2 .

As regards topical treatments (Table 5 ), the majority part of patients (98.3%) was under treatment or had received topical corticosteroids, at least once in their life (98.7% of patients with mild adult AD, 97.1% of patients with moderate adult AD, and 98.5% of patients with severe adult AD had experience of treatment with topical corticosteroids) with an increasing trend, moving from mild to moderate and severe AD ( p = 0.003).

For HbA1c levels, no significant differences were observed among obesity groups in the baseline, but HbA1c levels had an increasing trend (p-value = 0.003 in linear trend) and show significant differences in the follow-up (SI Fig.

Before intervention, the positive density of MDRO in the orthopedic ward showed an increasing trend (β 1 = 0.02, P = 0.003).

An increasing trend of patients achieving glycemic control (<7%) was shown throughout follow-up ( p =0.003).

There was an increasing trend in patients undergoing TAVR with obesity ( p = 0.016) and smoking ( p < 0.001), while a negative trend was observed in patients with peripheral vascular disease, the prevalence of which decreased from 32.5 to 19.8% ( p = 0.003).

Dopamine and norepinephrine were associated with an increasing trend in serum K + concentrations (β = 0.584; SE = 0.196; p = 0.003 and β = 0.811; SE = 0.251; p = 0.001, respectively).

Over this period, the age-standardized prevalence rates of stroke exhibited an increasing trend: 1450.8, 1935.9, 2337.4, 2667.3, and 3024.5 per 100,000 ( p = 0.003).

The MI values displayed an increasing trend during the experiment (Friedman’s test, χ 2 (2) = 11.444, p value = 0.003), with the multiple comparison tests being statistically significant between the initial and the post condition (V = 10, Bonferroni-corrected p value = 0.980e−3).