“an increasing trend”

The ITS analysis showed an increasing trend in NLHC uptake (9.25, 8.98–9.52, p < 0.001) pre-P4P, a step change of −22.9 (−24.5 to −21.2, p < 0.001), and a sustained decrease in trend of −7.10 (−7.88 to −6.33, p < 0.001) in NLHC uptake overall ( Table 2 ).

The age‐adjusted incidence rate (AAIR) of primary renal lymphoma was 0.035/100 000 population, and an increasing trend was observed during the study period with an AAPC of 3.3% (95%CI: 1.4‐5.3, P < . 001) from 1984 to 2015.

The percentage of appropriate prescriptions per month showed a different trend between physicians and non-physicians (Table 2 ); in particular, an increasing trend was observed in physicians (β = 0.07, SE: 0.01, 95%CI: 0.04; 0.10, p < 0.001), while a significant decrease was observed in non-physicians (β = -0.13, SE: 0.05, 95%CI: -0.23;-0.03; p = 0.013).

Risk Factor Analysis of 5-Year Survival after Surgery The 5-year overall survival (OS) of all patients was 69.3%, and the mortality rate showed an increasing trend according to the stage ( p < 0.001).

Association between perceived stress and fat intake The correlation between fat intake and perceived stress as numerical variables was significant (ρ = 0.15, p-value = 0.005), and there was evidence of an increasing trend of fat intake associated with greater perceived stress (p<0.001).

In oropharyngeal carcinoma, which showed an increasing trend of HPV prevalence over time ( P < 0.001), HPV infection was inversely correlated with tobacco smoking, alcohol drinking, p53 mutations, and a disruptive mutation ( P = 0.003 , <0.001, <0.001, and <0.001, respectively).

Patients admitted for intertrochanteric fractures also experienced a shorter hospital length of stay and an increasing trend towards early fracture fixation ( p < 0.001), with a greater usage of intramedullary nails in the treatment of such fractures ( p < 0.001).

Results The serum levels of 25(OH)D, 25(OH)D3, and F25(OH)D showed a decreasing trend ( z = −2.781–−3.996, P < 0.01) in RA patients with CKD progression from mild to severe, while C3-epi-25(OH)D3 showed an increasing trend ( z = 6.741, P < 0.001) and 25(OH)D2 showed no significant difference among the groups ( z = 0.976, P = 0.329).

The odds of GDM had an increasing trend according to the BMI (p < 0.001).

4a ) indeed exhibits an increasing trend with the latitude ( r = 0.27, P < 0.001), suggesting a certain association with IGWs.

The mean (SE) age was 59.7 ± 0.49 years among patients who did not undergo ERCP, increasing to 65.1 ± 0.19 years in the late ERCP group, thus showing an increasing trend ( P < 0.001).

Inflammatory markers measurement As seen in Figure 6 , the production of IL-6 and TNF-α in ethanol treatment group had an increasing trend as compared with the control group in the liver ( P< 0.001 and P< 0.05, respectively).

The mean BI score showed an increasing trend over time, with a significant difference ( F = 42.90, p < 0.001).

Clinical parameters, such as BMI, WC, SBP, DBP, FPG, 2hPG, HbA1c, FINS, HOMA-IR, ALT, AST, GGT, TG, TC, and LDL-C, displayed an increasing trend from quartile 1 to quartile 4 (all P < 0.001; Table 2 ).

Group 2 (abnormal at 0h, but normal at 1h and 2h), Group 3 (normal at 0h, but abnormal at 1h or 2h), and Group 4 (abnormal at 0h, 1h or 2h) showed an increasing trend in APO risk compared to Group 1 (normal at three time points), with adjusted OR of 1.14, 1.18, and 1.42, respectively ( P <0.001).

The proportion of individuals with BMI ≥ 25 kg/m2 increased from 52.3% in 2014 to 54.3% in 2018 ( p < 0.001), while the percentage of participants with FPG ≥ 130 mg/dL also showed an increasing trend ( p < 0.001).

Tissue HER2 CN with ddPCR showed an increasing trend according to the HER2 IHC grade (P < 0.001, Fig. 1b ).

1 A], but not significant in subgroups; proportion of 30-day ART initiation showed an increase trend of 1.0% per month before treat-all (IRR = 1.010, 95% CI : 1.001–1.018; P = 0.030), and after treat-all showed an increasing trend of 0.8% per month (IRR = 1.008, 95% CI : 1.006–1.010; P < 0.001); by the end of 2019 (December 2019), proportion of 30-day ART initiation was not significantly different from the expected level (IRR = 1.044, 95% CI : 0.681–1.600; P = 0.844).

Through trend test analysis, the clozapine serum concentration showed an increasing trend with increasing drug dose ( p < 0.001), and the C/D ratio showed a decreasing trend with increasing daily drug dose ( p < 0.001) (Table 3 ).

Moreover, there has been an increasing trend of 0.002 yr −1 ( P < 0.001) in vegetation cover ( Fig. 2 ).

CAR showed an increasing trend in the oral mass and metastasis groups (10 times and 100 times, respectively) compared to the no oral mass group ( P < 0.001).

In contrast, the average menstrual cycle length exhibited an increasing trend ( P < 0.001, P -trend < 0.001), while both the average number of menstrual periods per year and the number of ovulatory cycles showed significant decreasing trends ( P < 0.005, P -trend < 0.005), with the Q4 group being significantly lower than the Q1 and Q2 groups.

The fluorescence intensity was markedly high in class 3, and an increasing trend of fluorescence intensity with classification was confirmed by the Jonckheere–Terpstra test ( P < 0.001).

The median age of the affected general population (37 years) had an increasing trend (from 30.8 years in 2009 to 40.5 in 2018, P < 0.001) and was significantly higher than that among Roma and migrants (7 and 8 years, respectively, P < 0.001).

An increasing trend in mean HbA1c was found in healthy and high-risk hosts (healthy hosts, 0.07 ± 0.02% [ P < 0.001]; high-risk hosts, 0.10 ± 0.03% [ P < 0.001]; Table 2 ).