“an increasing trend”

An analysis using the Mann–Kendall Trend Test identified an increasing trend from 6 am to 6 pm ( p -value < 0.001) and a decreasing trend from 6 pm to 6 am ( p -value < 0.001).

Custom interval analyses further demonstrated a declining trend before the pandemic (1999–2019; AAPC=-0.2709%, 95% CI:-0.4281 to -0.1087, P < .001) and an increasing trend during the pandemic period (2020–2024; AAPC=1.2879%, 95% CI: 0.9922 to 1.6558, P < .001).

In oropharyngeal carcinoma, which showed an increasing trend of HPV prevalence over time ( P < 0.001), HPV infection was inversely correlated with tobacco smoking, alcohol drinking, p53 mutations, and a disruptive mutation ( P = 0.003 , <0.001, <0.001, and <0.001, respectively).

( 2 ) based on the GBD2019 dataset showed that the variation trend of incidence for birth defects between 1990 and 2019 globally was not statistically significant, but showed an increasing trend in China ( p < 0.001), with an annually percentage changes of 0.26%, and the upward trend was projected to continue between 2020 and 2030.

Further stratification of patients into asymptomatic, mild, moderate, and severe infections highlighted an increasing trend in viral load concentrations (Fig. 2B , right), with significant differences in median viral loads overall across all severity levels ( P < 0.001 by Kruskal-Wallis H test).

A change in the type of admission for colorectal patients was observed, with an increasing trend towards elective cases in the latter group (p=0.001).

The majority (64.29%, 54/84) of the patients underwent laparotomy, and an increasing trend of minimally invasive surgical approaches (p<0.001) and fertility-sparing techniques (p<0.001) was observed.

During pre-COVID-19 outbreak, all stroke subtypes had an increasing trend with a coefficient of 0.076 ( p value < 0.001) for thrombotic stroke, 0.003 ( p value < 0.001) for embolic stroke and 0.012 ( p value = 0.025) for hemorrhagic stroke.

Whereas agency terms in the antisemitic text showed no significant trend before the Holocaust, agency terms in the control text showed an increasing trend during this time, b 1 = 0.01, 95% CI [0.005, 0.011], SE = 0.001, t = 4.92, p < .001.

With the increase of CMI levels, the risk of CMD showed an increasing trend, p < 0.001.

In these groups as well, sensitivity analyses excluding the year 2020 confirmed an increasing trend in sudden death–attributable mortality in both sexes [AAPC: +2.7% (95% CI: 1.8–4.0), p < 0.001 in men; and AAPC: +3.0% (95% CI: 2.0–4.5), p < 0.001 in women, respectively].

Results The A1A2 measured by CT exhibited an increasing trend from C3 to C7 segments in both groups ( P < 0.001).

In the period before PrEP enrollment, there was an increasing trend in quarterly C trachomatis or N gonorrhoea positivity (RR increase, 1.08 per quarter [or an 8% increase per quarter]; 95% CI, 1.05-1.11 per quarter; P < .001); however, no trend was observed after starting PrEP (RR increase, 1.01 per quarter; 95% CI, 0.99-1.02 per quarter; P = .29).

It means an increasing trend in the prevalence of hyperuricemia with the higher TyG index ( p <.001).

In contrast, the average menstrual cycle length exhibited an increasing trend ( P < 0.001, P -trend < 0.001), while both the average number of menstrual periods per year and the number of ovulatory cycles showed significant decreasing trends ( P < 0.005, P -trend < 0.005), with the Q4 group being significantly lower than the Q1 and Q2 groups.

An increasing trend for the risk was observed from the low-risk group to the high-risk group in both the training and validation sets (p value < 0.001 and p value = 0.001, respectively) (Table 6 ).

Furthermore, an increasing trend was observed in the level of TG and hs-CRP in three different BMI groups of both sexes ( P < 0.001).

The overall prevalence (per 100,000 persons) also showed an increasing trend, from 3065.76 (95% CI: 3051.68–3079.88) to 6296.38 (95% CI: 6277.02–6315.78), with an AAPC of 6.69% (95% CI: 6.45–7.03; p < 0.001) ( Fig. 1 a, Table 3 , Supplementary Table S2 ).

The theft rate exhibited an increasing trend before the pandemic, with a monthly significant increase of 2.1% (IRR = 1.021; P < 0.001).

The incidence showed an increasing trend as estimated by linear regression ( P < 0.001).

During the same period, the global age-standardized incidence rate (ASIR) exhibited an increasing trend (AAPC = 0.05%, 95% CI: 0.03–0.07, P < 0.001), reaching 150,291.52 per 100,000 in 2021 ( Table 2 , Figure 1B ).

There was an increasing trend of albuminuria (UACR ≥30 mg/g) from control, HTN1, HTN2 to HTN3 group (4% vs. 12.1% vs. 14.9% vs. 19.6%, χ 2 = 38.886, p < .001).

Resilience showed an increasing trend during the four tests (Slope = 0.56, p < 0.001), and the rate of increase increased month by month (Linear Slope = 0.28, p < 0.01).

Sample seroprevalence in muskoxen varied geographically with an increasing trend of exposure on NW Victoria Island (from 0% to 36.8% between 2016 and 2022; Kendall tau = 0.283, p = 0.001).

Inflammatory markers measurement As seen in Figure 6 , the production of IL-6 and TNF-α in ethanol treatment group had an increasing trend as compared with the control group in the liver ( P< 0.001 and P< 0.05, respectively).