Though none of SNPs were validated at the pre-defined significance thresholds, two SNPs (rs1394384 and rs1381392) showed a trend towards significance.
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“a trend towards significance”
In the literature
Nonetheless, since that time, Chalermskulrat et al., showed that the number of combined HLA-A and HLA-B mismatches were strongly associated with BOS stage with a trend towards significance seen with HLA-DR mismatches [ 49 ].
A trend towards significance was observed for consanguinity (Table 3 ).
Age showed a trend towards significance with a P value of 0.091.
In our study, we observed a mean decrease in muscle mass of 2.07% (SD = 8.74, SE Mean = 1.12), with a p -value of 0.06, indicating a trend towards significance.
In addition, pH ( p = 0.07) and amylase levels ( p = 0.09) displayed a trend towards significance ( Table 2 ).
Interestingly, the expression of TGFBR2 and BMPR2 showed a trend towards significance and suggests that high expression levels of these genes are associated with lower rates of patient survival.
From the optional criteria, the clearest applicability could be found for “variations in intensity associated with stress” while “nocturnal variations” showed only a trend towards significance.
This difference was no longer significant after controlling for maternal age and paternal ethnicity ( F (1, 76) = 2.99, p = .088), although there was still a trend towards significance.
In terms of prognostic impact, in the overall population, no statistically significant correlation of LDH levels with clinical outcome was evident in PFS (high vs low HR: 1,22 (95% CI: 0.88–1.68), P : 0.232), and a trend towards significance was reported in OS (high vs low HR: 1.35 (95% CI: 0.96–1.88), P : 0.081).
PALS in the RHD group was lower compared to MVP(p = 0.08) which showed a trend towards significance.
Orchiectomy decreased serum testosterone levels in all age groups but this was only significant (two-way ANOVA) in the 1.5- and 5-month-old cohorts ( Fig 1A ), although there was a trend towards significance in the 12-month-old cohort (multiple T-test showed significance).
However, there was a trend towards significance in the interaction for the number of pro-embryos ( p -value of 0.097).
There was also a trend towards significance for a decrease in sudden bouts of fatigue during the day, particularly after three months of CPAP use.
While there was no intra or intergroup difference of response to Q1 nor Q2, the response change in Q2 for the intervention arm (“I feel like I have good coping skills with my depression.”), demonstrated a trend towards significance.
Even though, there seems to be a trend towards significance and a larger number of isolates would be required to investigate the finding further and these results could suggests that clinical non-CF isolates may have an evolutionary background that is distinct from isolates colonizing CF patients.
While in the univariate analysis previous physical activity was a significant protective factor and in the multivariable analysis it showed a trend towards significance, current physical activity was not associated with CI.
On contrast-enhanced CT there was only a trend towards significance [ 40 , 41 ].
In hyposmic patients there was a trend towards significance for poorer odor imagery compared to controls.
PAI-1 demonstrated a trend towards significance in overall survival (OS) in the late-stage TN cohort, and correlation between PAI-1 and neutrophils in this cohort was significant. 72.7% (16/22) of TN patients with plasma PAI-1 levels higher than OS cutoff were CTC-positive.
In the auditory task, the perceived TC was significantly stronger in the active trials compared with the passive ones at 400 ms of delay between the movement and its consequence, with a trend towards significance at 600 ms.
A p-value <0.05 was considered statistically significant, while a p-value ranging from 0.05 to 0.1 indicated a trend towards significance.
There was a trend towards significance for the perceived use of lecture capture to support learning with those receiving captions and transcripts giving a higher perceived usefulness score.
For applicants with cancer, respiratory diseases and multimorbidity, inability to work fulltime showed a trend towards significance in being negatively associated with having paid employment a year later.
Although escape fantasy ( p =0.062) and absence of fear ( p =0.074) are not significant at the conventional 0.05 level, they show a trend towards significance.