Barely Significant
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“a trend towards significance”

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= 1), P = 0.032 (see Table III). Clinicopathological associations and patient survival There was a trend towards significance of p53 expression and increased regional tumour recurrence in 143 patients on whom recurrence data was available x2 = 3.20 (d.f. = 1), Table II Tumour p53, EGFR and c-erbB-2 immunoreactivity and tumour grade Tumour p53 EGFR c-erbB-2 Grade POS/NEG POS/NEG POS/NEG 1 3/18 5/16 3/18 2 15/32 12/35 20/27 3 43/35 31/47 35/43 P<0.001 (S) P = 0.16 (NS) P = 0.035 (S)a a(S) Statistically significant; (NS) Not statistically significant. 58S 586 D.N.
The metastatic spread of hvKP1 from the subcutaneous compartment to the blood, eye, kidney, spleen, liver and lungs was greater when hvKP1 was grown in the presence of conditioned ascites, compared to unconditioned ascites at all times post-bacterial challenge (24 and 48 hours) and this difference was statistically significant or demonstrated a trend towards significance for most comparisons ( Figure 5 ).
Discussion The main findings of this study indicated that treatment with stem cell-based regenerative therapies and derived products significantly improved exercise capacity in COPD patients and produced a trend towards significance for an improvement in FEV 1 , but no other lung function parameters showed a significant difference compared to baseline or CTL.