Additionally, a trend towards significance was observed for the last 6 months BAARS-IV Inattention subscale ( p = 0.08), suggesting greater attentional difficulties in the ADHD + ASD group compared to the ASD group.
Results for all groups are presented in Table 1 . Subjects who received the highest dose of CPL-01 in Cohort 3 had a mean (SD) AUC 0-72 of 286.8 (113.70), which was the lowest value for any treatment group in all cohorts, showing a trend towards significance as compared to the pooled placebo group (mean AUC 0-72 of 369.2, p = 0.08) and numerically lower than the mean (SD) AUC 0-72 of 322.5 (176.63) for the pooled NAROPIN group.
Multivariate survival analysis, limited by small numbers, demonstrated a trend towards significance for cytotoxic chemotherapy as an independent predictor of mortality with a HR 1.93 (95% CI: 0.93–4.00, p = 0.08), while the other individual treatment modalities were not associated with significant differences in COVID-19 mortality ( Table 2 ).
11 The multicenter, randomized FAST trial explored the effect of low-dose prednisone and intravenous (iv) CYC for 6 months, followed by maintenance AZA in SSc-ILD. Compared with placebo, predicted FVC in the treatment group improved by 4.2%, but only with a trend towards significance ( p = 0.08) after 12 months. 17 Due to potential bladder toxicity, continuing CYC long-term is challenging.
Correlation between PMNs mobilization and CXCL1 plasma levels was also evaluated and we found a clear significance (r = 0.66, p = 0.001) when animals of all groups were included (n = 28) and a trend towards significance (r = 0.71, p = 0.08) when only ischemic animals were evaluated (n = 7) (Data not shown).
The next two most significant associations observed were for raised lesions in the abdominal and the thoracic aorta with p values that showed a trend towards significance (p = 0.08 and 0.11, respectively).
Glucose levels of β2-KO mice were significantly lower at 15 and 30 min after insulin injection compared to WT littermates ( Figure 2 d), with differences in the AUC showing a trend towards significance ( p -value = 0.08) ( Figure 2 e).
There was a trend towards significance between the SLC samples ( Figure 4 ) and the corresponding unprocessed controls ( P < 0.08) at 0 h although the difference was significant at 24 h ( P < 0.01) and at 72 h ( P < 0.001).
When patients on both vincristine dose arms were included, the 3-year DFS maintained a trend towards significance (73.1±5.6% for HCT vs. 65.6±4.0%, P =0.08).
2 D) and a trend towards significance in the hippocampus ( p = 0.0806; Fig. 2 D).
We compared TMEV mRNA expression between 4 dpi and 14 dpi for each strain and observed a trend towards significance for CC023 ( p = 0.0809) and CC027 ( p = 0.0809).
Although we did not detect significant differences between 4 dpi and 14 dpi for these strains, there was a trend towards significance for CC023 ( P = .0809) and CC078 ( P = .0809).
Correlation between medication use in weeks and plasma DDC activity showed a trend towards significance (r τ = −0.195, p = 0.081).
There was only a trend towards significance in the Bonferroni test between nursing ( M = 18.987, SD = 6.186) and medical students ( M = 16.030, SD = 3.687) with a mean difference of −2.957 ( p = 0.081).
However there was a trend towards significance for the RAPM ( F (1, 24)=3.318, p =.081, η p 2 =.121). 3.9.3.
The angle DSD, which describes the opening angle of the cleft area, tended to be wider in the PRS group (69.48° ± 14.34°) than in the CPO group (63.59° ± 8.20°); however, only a trend towards significance could be observed here ( P = 0.081).
A trend towards significance was observed in the correlation between the absolute IOP values 18 months after PRESERFLO® implantation and the RNFL reduction during this period ( r = 0.38, p = 0.081).
We found a significant association between the neurochemical profiles observed for ketamine and autism in ABIDE2 ( r (14) = 0.563, p = 0.023, 95% CI [0.094, 0.828]) and a trend towards significance for ABIDE1 ( r (14) = 0.448, p = 0.081, 95% CI [−0.061, 0.772]) (Fig. 2B ).
A trend towards significance was noticed when comparing Dysf BCs, Funct BCs and healthy controls ( p = 0.081).
First, we explored gene signatures of antigen presentation and processing and found that only reduction of a B cells signature, in the comparison classical tumours vs preinvasive lesions, had a trend towards significance (p = 0.081) (Fig. 4a ).
The comparison of the weighted average degree showed that both PD-CN and PD-MCI patients presented a lower number of connections compared to controls (PD-MCI = 172.6; PD-CN = 175.2; controls = 183.7), which showed a trend towards significance in the comparison with PD-CN (p-value = 0.081) and was statistically significant in the comparison with PD-MCI (p-value = 0.027).
We next assessed the expression levels of CD3ζ in CD4 + and CD8 + T cells in PBMCs: statistically significantly lower CD3ζ MFI in CD4 + T cells from patients before treatment (15.4±0.6) was observed as compared to controls (20.0±1.3, p = 0.0008); higher CD3ζ MFI in CD4 + T cells that shows a trend towards significance was observed in the treated patients (17.4±0.8, p = 0.081)( Figure 6B ).
In particular, we detected significant differences in ACC mI ( p = 0.038) and PCC tCho ( p = 0.033) and a trend towards significance in PCC tCr ( p = 0.081), LHIPPO mI ( p = 0.061), and RHIPPO tCr ( p = 0.054).
A trend towards significance was also observed for emergency department visit rates ( p = 0.081) in the pre-population ( n = 359, 14.8%) compared to the post-population rate of 12.8% ( n = 205) (Table 3 ).
The likelihood ratio for for-profit vs not-for-profit status was not significant for any of the quartiles; however, there was a trend towards significance for quartile 4 (Q4: LR = 3.05, P = 0.081), implying possible concentration of for-profits in the bottom quartile (Other quartiles Q1: LR = 1.51, P = 0.219; Q2: LR = 0.51, P = 0.474; Q3: LR = 0.95, P = 0.329).