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“a trend towards significance”

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a trend towards significanceP = 0.0801.6× alpha
In regression analysis including all participants, neither TMD nor migraine as main effects were associated with the plasma CGRP concentration ( P = 0.761 and P = 0.972, respectively), and no statistically significant TMD × migraine interaction was noted ( P = 0.696) ( Table 2 ). Association Between Plasma CGRP Concentration and Participants’ Characteristics In analyses including all participants, participant age was the only characteristic statistically significantly associated with plasma CGRP concentration ( P = 0.034), while the association with BMI showed a trend towards significance ( P = 0.080) ( Table 3 ).
a trend towards significancep = 0.081.6× alpha
Chronic Effects Numeric working memory accuracy evinced a significant pure chronic interaction between “treatment × repetition” on day 29 in favour of sage, F(2, 184) = 4.49, p = 0.01, with post-hoc ANOVAs revealing no significant effects at pre-dose, F(1,93) = 0.80, p = 0.37; a trend towards significance at post-dose repetition 1, F(1,93) = 3.1, p = 0.08; and no significant difference at post-dose repetition 2, F(1,93) = 0.07, p = 0.79.
a trend towards significancep = 0.081.6× alpha
Correlation between PMNs mobilization and CXCL1 plasma levels was also evaluated and we found a clear significance (r = 0.66, p = 0.001) when animals of all groups were included (n = 28) and a trend towards significance (r = 0.71, p = 0.08) when only ischemic animals were evaluated (n = 7) (Data not shown).
a trend towards significancep = 0.081.6× alpha
Results for all groups are presented in Table 1 . Subjects who received the highest dose of CPL-01 in Cohort 3 had a mean (SD) AUC 0-72 of 286.8 (113.70), which was the lowest value for any treatment group in all cohorts, showing a trend towards significance as compared to the pooled placebo group (mean AUC 0-72 of 369.2, p = 0.08) and numerically lower than the mean (SD) AUC 0-72 of 322.5 (176.63) for the pooled NAROPIN group.
a trend towards significancep = 0.081.6× alpha
Multivariate survival analysis, limited by small numbers, demonstrated a trend towards significance for cytotoxic chemotherapy as an independent predictor of mortality with a HR 1.93 (95% CI: 0.93–4.00, p = 0.08), while the other individual treatment modalities were not associated with significant differences in COVID-19 mortality ( Table 2 ).