Statistical significance was set at P < 0.05, and at P < 0.1 a trend toward significance was considered.
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“a trend toward significance”
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Significant difference is denoted as P < 0.05, and a value of 0.05 ≤ P < 0.10 is interpreted as a trend toward significance.
MPH was also found to be a potential favorable prognostic finding since it showed a trend toward significance with longer OS in IP; this positive predictive value needs to be further investigated implementing the caseload.
The difference between the synchronous and asynchronous conditions was smaller for the needle compared with the brush stroke stimuli (even though the Condition × Stimulus interaction only showed a trend toward significance).
Although there was a trend toward significance for IL-1β between the thrombotic cohort and non-thrombotic cohort, it did not reach statistical significance (18 vs. 11.5, p = NS).
Though there was a trend toward significance, we did not find a statistically significant difference in the area of vascular obliteration between conditions ( Figure 2D ).
Differences were considered significant at P < 0.05; when P > 0.05 but P < 0.1, differences were considered to indicate a trend toward significance.
26 , 27 , 28 , 29 , 67 They correspond to the findings of Mulhauser et al, 73 who only found a trend toward significance when comparing hypersexual and nonhypersexual males according to their level of impulsivity.
6 - 9 Indeed, a recent meta-analysis showed a trend toward significance for a mortality benefit with surgical stabilization. 10 However, there is significant selection bias in the existing literature because many series identify differences between surgical and nonoperative groups, but do not control or adjust for them. 5 , 8 , 10 - 18 In the trauma context, 30-day mortality may be driven by associated injuries other than the odontoid fracture itself.
Since the interaction effect showed a trend toward significance, we also performed pairwise mixed models.
Similarly there were significant reductions or there was a trend toward significance for reduction in total missed areas and intermediate (300 – 1000 mm 2 ) sized missed areas between the no-antispasmodic group and both the 20-mg and 40-mg groups, but not between the 20-mg and 40-mg groups ( Table 2 ).
In exploratory analyses stratified by sex, sexual minority disparities in prevalence of smoking post-cancer showed a trend toward significance among females, not males.
While nivolumab combined with ipilimumab showed benefit in terms of mPFS (HR = 0.58, 95% CI: 0.41‐0.81), PFSR1y (RR = 0.30, 95% CI: 0.20‐0.47) and ORR (RR = 0.59, 95% CI: 0.43‐0.81) (all P < 0.05), and a trend toward significance of PFSR6m (RR = 0.82, 95% CI: 0.66‐1.01) compared with chemotherapy (Figure 3 ).
The main effect of the IVIG response group was not significant (P(group) = 0.287), while the time-by-group interaction showed a trend toward significance (P(interaction) = 0.087).
This study demonstrated a significant association of Cryptosporidium infection during year 1 and linear growth faltering at 24 months of age in INV and a trend toward significance in BDG, consistent with a prior study from this region [ 9 ].
Mann–Whitney U-test detected a trend toward significance, indicating that haloperidol and UNC9994 given alone increased pAkt-S473 level in comparison with the vehicle-treated group (both P ’s = .08).
When age was included as a covariate, several results lost significance, especially in the aDS group, but the associations with NfL remained significant or showed a trend toward significance in the whole DS and sDS cohorts (Figure 5S in supporting information). 3.6.
Statistical analyses were performed at α = 0.05 two-sided significance level; α between 0.05 and 0.1 was considered a trend toward significance.
Tibial bone from the high-fat group also had significantly lower cross-sectional bone perimeter (B.Pm), cross-sectional thickness (Cs.Th), cortical thickness, and cortical bone area (B.Ar/T.Ar, 8.6%) and the femoral bone showing similar decreases with a trend toward significance ( Table 3 ).
This meta-analysis of 10 observational studies also did not show a statistically increased risk of cancers in patients taking TNF-I (RR 1.42, 95% CI 0.72–2.79) ( Figure 4 ) but did suggest a trend toward significance with both longer exposure to TNF-I and longer follow-up.
Although statistically insignificant, positive for FANA showed a trend toward significance in the multivariable analysis for LAF score 2 sinusoidal fibrosis.
Male sex was significantly associated with outcome in univariate analysis, showing a trend toward significance in multivariate analysis.
However, it is worthy of mentioning that the association findings between the FA values and PANSS symptom scores in either male or female patients did not pass Bonferroni corrections or only showed a trend toward significance.
12 , 15–20 Three out the four remaining studies showed a trend toward significance between low p27 Kip1 protein levels and poor disease outcome.
The association between IDO1 levels and clinical outcomes remained significant in a multivariate model that included all clinical parameters that either were significant or showed a trend toward significance on univariate examination (Table 3 ).