“a trend toward significance”

A one-way ANOVA comparing all pairs of mean slopes with Tukey-Kramer correction for multiple comparisons was used to show that Δ379 has significantly higher current at both −100 mV and +60 mV compared to mock, FL, or pAlaExt (p<0.05), while FL and pAlaExt were not significantly different than mock (though there was a trend toward significance in the case of FL at +60 mV).

A trend toward significance was observed for the SOFA value at IAI presentation.

When considering alleles individually, the logistic regression did not reveal any significant associations; however, the C allele of ERBB4 rs839523 showed a trend toward significance.

While there was a trend toward significance in the ARC, there were significantly more GFP+ cells in the ME in tumor‐bearing animals compared to sham animals (Figure 2 c).

Statistical significance was accepted at P less than 0.05, and a trend toward significance was detected for P values ranging from 0.05 to 0.10.

Moreover, we found lower frequency of creativity in de novo drug naïve RPD according to the MDS-UPDRS motor score dichotomy and a trend toward significance when considering the side of motor onset.

Covariates included in the final Cox model were selected through a two‐step process: (i) exploratory Cox models grouping demographic, tumor‐related, and epilepsy‐related variables were first tested independently; (ii) variables showing a trend toward significance or strong clinical plausibility were retained in order to avoid overfitting while preserving control for potential confounders.

The effect of laxative as a pre-treatment rectal preparation was also found to show a trend toward significance for SF-18 and T-18.

Unconjugated bile salt species Of unconjugated BSs, chenodeoxycholate (CDC) was the only unconjugated BS species that showed a trend toward significance between the NEC group and the controls.

For the other IMU derived metrics it is possible to appreciate a trend toward significance ( Table 3 ). 3.2.

Logistic regression showed a trend toward significance, but the association was not statistically significant ( p = 0.051) (Fig. 4 b).

There was a trend toward significance for a higher dysglycemia percentage in people with CT and TT genotypes (25.7%, and 23.3%, respectively) compared with CC genotypes (16.2%).

Although statistical significance was not achieved for the PMN-MDSC proportion change in the spleen of Hu-NSG, a trend toward significance was observed between the three groups (Fig. 7D ).

Bioinformatic analysis of data from The Cancer Genome Atlas (TCGA) revealed a modest correlation between high CST3 expression and poor overall survival across all cancer patients ( P > 0.05, but with a trend toward significance; Supplementary Fig. 8b ).

Although there was a trend toward significance between the Nox2 +/+ EAE and the Nox2 +/+ control groups, IL-6 protein levels were not significantly increased in the striatum of either Nox2 +/+ and Nox2 -/- mice after EAE ( Fig. 6 ).

Caspase-1 gene expression was unchanged and protein levels showed a trend toward significance at DS1.

Meanwhile, combining pGSN with IL-6 (AUC=0.904; p=0.003) showed a more significant ability to predict mild COVID-19 and IP-10 (AUC=0.754; p=0.065), HGF (AUC=0.746; p=0.075) and TGF-β1 (AUC=0.765; p=0.078) demonstrated a trend toward significance ( Figure 5A ; Supplementary Figure S4C ) .

All statistics were calculated using GraphPad Prism software (ver8, GraphPad, La Jolla, CA, RRID:SCR_002798) and were defined as significant if p < 0.05; however, p value < 0.1 was also reported to demonstrate a trend toward significance.

45M1 expression was lower, with a trend toward significance in the NAT group ( Table 2 ).

However, there was a trend toward significance for brain metastases in relation to PFS, which aligns with findings in the literature.

Major complications were more common in the relative (OR = 5.5, P = 0.057) and absolute indication arm (OR = 5.231, P = 0.051) with a trend toward significance.

Furthermore, an educational level of college or above ( p = 0.053), monthly income ( p = 0.067), religious belief ( p = 0.073), physical component summary ( p = 0.073), mental component summary ( p = 0.099), and objective support ( p = 0.055) showed a trend toward significance (borderline significance) (see Table 3 for details). 4 Discussion 4.1 The crucial enabling role of legal support in enhancing the willingness to establish a living will Middle-aged and older adults’ understanding of the legal knowledge related to creating a Living Will is positively correlated with the positivity of their willingness.

These additional analyses (Appendix B ) replicate the pattern of significance reported for the full sample, but to a trend toward significance in the analysis of intervention gains in untrained fractions. 3.1.4.

A trend toward significance difference in TMT-A were found for the effect of the MI between the two groups (pre-frail or not).

Finally, both intepirdine groups failed to demonstrate a statistical benefit over placebo on any of the tertiary endpoints at week 24, although there was a trend toward significance favoring the 70 mg/day group on the COWAT score and the NPI Parts A+B subscore (Table 2 ).