TMB level was lower in ICI-resistant patients than in ICI-sensitive patients with a trend close to significance (median TMB 20.8 vs 29.3 mutations/Mb, p=0.051) ( figure 4A ), while no significant difference was found in the rest parameters ( online supplemental figure 8 ).
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ABS–A reduction in strength of −2.9 MPa, with a trend close to significance ( p = 0.0529).
In addition, long jump showed significant Poisson regressions, while triple jump showed a trend close to significance ( p = 0.054).
Although the Barthel Index [ 26 ] showed a trend close to significance ( p = 0.0545), it did not reach the conventional statistical threshold, so it is recommended to evaluate this possible pattern in studies with larger sample sizes. 4.
There was a trend close to significance for a longer metastasis-free survival in patients with low phosphorylated Smad2, corresponding to a sum score lower or equal to 3 (p=0.055) (Figure 2 D).
When analyzing the different delays, an effect of group was detected in the 6 s delay (F 1,35 = 4.198; p < 0.05; partial η 2 = 0.107), as well as a trend close to significance in the 12 s delay (F 1,35 = 3.885; p = 0.057; partial η 2 = 0.1), but no effect was noted in the others.
A two-way ANOVA showed a trend close to significance for the object effect ( F 1, 18 = 4.01, P = 0.06) and genotype × object interaction ( F 1, 18 = 4.20, P = 0.055).
A trend close to significance was found in RAVLT-I, in which ET-RBD patients performed worse (p = 0.060).
The expression of LRb transcripts in the VMH/DMH was not significantly different between sheep groups; however, a trend close to significance ( p = 0.06) was observed in the Lean-R group.
Of course, the variable left chest pain showed a trend close to significance (p=.066).
In addition, the concurrence of pre-existing CLD might be a potentially relevant factor with a trend close to significance for fatal outcomes of HILI (p=0.078).
However, a comparison between WL and FF conditions showed a trend close to significance [ t (10) = 1.961; p = 0.078].
A trend close to significance was apparent for type 2 diabetic patients (p = 0.08) and with airway obstruction (p = 0.11).
Statistical analysis of clinical characteristics showed that high DDR2 expression was highly correlated with lymph node metastasis ( p =0.037) and positively correlated with clinical stage at a trend close to significance ( p =0.082, Supplementary Table 1 ).
The AR-V7-positive patients exhibited a significantly higher proportion of any site metastasis (61.3% versus 35.0%; OR 2.19, 95% CI 1.57–3.05, p < 0.001) and bone metastasis (81.7% versus 69.0%; OR 1.97, 95% CI 1.44–2.69, p < 0.001), and a trend close to significance was expected in visceral metastasis (28.8% versus 22.1%; OR 1.29, 95% CI 0.96–1.74, p = 0.09).
Although no statistical significance was achieved in the χ 2 test (χ2 = 2.949; P = 0.086), the Fisher exact test showed a trend close to significance ( P = 0.097).
In addition, these two clusters, together with T23 which was increased with a trend close to significance, had a mutual, significant, and negative relationship with the concentrations of LDL and TCHO in the blood (Fig. 5 D and E).
45 , 46 The analysis of the correlations demonstrated a trend close to significance between obsessions and compulsions, namely aggression, and symmetry/ordering/rearrangement in the BU-OCD group.
PCT had a trend close to significance to be lower for children with VUR ≥3 in the validation set compared with those in the derivation set: median = 1.5 ng/mL (IQR: 0.3–6.1) vs. 2.9 (IQR: 1.2–6.8); P = 0.06.
Values of p < 0.05 indicated a significant difference and 0.05 ≤ p < 0.1 was considered a trend close to significance to increase the sensitivity to detect potential selection bias.
A trend close to significance was also observed in the evaluation of ambulation ability (FAC).
Hospitalizations for acute coronary syndrome decreased only during the final smoking ban (period 4), where we measured a trend close to significance: adjusted IRR was 0.90 [95%CI: 0.80–1.00] for all patients and 0.89 [95%CI: 0.78–1.02] for Geneva residents ( Table 2 ).
Additionally, knockdown of DNM2 also significantly increased the proportion of late apoptotic cells in the presence of bortezomib and sEVs, and CLTC knockdown induced the similar effect with a trend close to significance (Figure 6 J-K).
However, proportional deviation from covariation plane evaluated by PV3 demonstrated a trend close to significance showing a better plane fitting after HAL therapy for acute but not for chronic group; quantitative comparison between PV3 before and after HAL therapy were close to significance for acute group only (Figure 3D , PV3 mean acute-pre: 0.03 ± 0.01, acute-post: 0.02 ± 0.007, chronic-pre: 0.013 ± 0.009, chronic-post: 0.012 ± 0.009.
When we tested the correlation of all six (three stimulation conditions × two genders) combinations, HS was only positively correlated with the D-IAT scores for both males ( ρ = 0.34, p = 0.057) and females in the sham stimulation ( ρ = 0.34, p = 0.061), a trend close to significance.