Neither M1-type nor M2-type gene expression signatures were significantly enhanced in these mice, though there was a suggestive trend in the M2 signature (Fig. 2d, e ; P = 0.32 for M2).
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In between-intervention comparisons, nivolumab had HRs of 1.44 (95% CrI: 1.00-2.06) versus bevacizumab and 1.31 (95% CrI: 1.06–1.63) versus rindopepimut, indicating a suggestive trend of relatively poorer survival (Figure S3).
At 18 month (n=197), the offspring born to obese mothers had lost five points in language composite scores and the previous differences in language and cognition was replaced by a suggestive trend of lower gross motor scores in the overweight, obese, and diabetic groups.
2 E), the positive associations did not reach statistical significance but showed a suggestive trend.
This was despite a suggestive trend of a reduction in the number of fish shedding for mixed infections compared to single infections in experiment 2 ( Fig 2B ).
In sum, published studies do not provide convincing evidence of an association between serum PFOA and increased IHD mortality, aside from a suggestive trend among the most highly exposed workers with a 10-year lag.
When looking at continuous differences in HDI, we observed a suggestive trend in the effect especially for congenital abnormalities, preterm birth and SGA ( Supplementary Figure S4 ).
In adjusted models, a suggestive trend across tertiles was observed for IL‐1β (trend p ‐value 0.01).
In the linear regression models adjusted for age, BMI and creatinine, we found a suggestive trend for lower serum INHB among women with higher urinary MEHP concentrations ( P- trend = 0.06) (Table 4 ).
In contrast, specificity was high, reaching 95.8% (95% CI 78.9%‒99.9%) in the total sample, and 100.0% in both the Gilbert and control groups, a suggestive trend that the CNN may be effective in correctly classifying non-dense breasts, though the preliminary nature of these results still necessitates further validation with larger cohorts.
Vaccinated patients exhibited a suggestive trend toward improved prognosis, with an adjusted odds ratio of 2.3 and significantly lower MEWS scores.
26 Finally, there was a suggestive trend of association between levels of pDES and the growth of aortic root diameter in MFS.
Investigating smoking cessation behaviors, there was a suggestive trend for association between age acceleration and recent smoke cessation only within females compared to males in the multivariate model.
The positive association below DI-GM = 3 (adjusted OR = 1.455, p = 0.064) should be interpreted as a suggestive trend rather than a statistically confirmed risk elevation, potentially reflecting limited statistical power or residual confounding; prospective studies are required for confirmation.
In those who did, there was a suggestive trend for median OS to be longer in patients expressing higher levels of PD-L1; however, there was a borderline statistically significant difference in PFS curves according to the duration of index nivolumab treatment (p = 0.046).
Additionally, a suggestive trend for association with reduced testicular volume was observed among young men, and with lower serum FSH among infertility patients.
We acknowledge that this does not reach conventional statistical significance (α = 0.05) and should be interpreted as a suggestive trend requiring confirmation.
However, such a difference was not observed, not even a suggestive trend (Supplementary Figure 4 ).
For both stages, P -values between the Bonferroni threshold and 0.05 were considered as a suggestive trend.
Therefor, in the intergroup comparisons of changes in upper airway indicators, the digital device is superior to traditional treatment in improving the minimum cross-sectional area of the upper airway, with a suggestive trend toward better outcomes in total airway volume and oropharyngeal volume.
In our multivariable model, we observed a suggestive trend with higher risks among survivors receiving etoposide within the HSCT with TBI group.
In a study of neonates with Neonatal Abstinence Syndrome (NAS), the addition of auricular acupressure beads did not result in a different clinical course, though there was a suggestive trend toward less pharmacological support in the acupressure group [ 71 ]. 4.1.12.
Meta-analyses have found that cemented stems are associated with significantly fewer intra- and postoperative periprosthetic fractures compared to cementless options. 3 Registry data support a 59% relative risk reduction with cemented stems. 4 In our study, we observed a clear inverse trend between preoperative YAM and intraoperative fracture risk, especially in underweight patients (BMI < 18.5 kg/m 2 ), with a suggestive trend despite not reaching statistical significance.
Specifically, among African Americans, there was a suggestive trend where ω-3 supplementation seemed to lower the risk of adenomas, hinting at a connection between ω-3 fatty acids and immune system adjustments.
Conversely, in the context of longer-distance ultra-marathon races, where the demands on aerobic and psychological endurance are heightened, there is a suggestive trend that athletes aged 45 years or over might exhibit enhanced performance.