The overall results showed that there was a strong trend but no statistical difference between the FIB-4 index and DFS in HCC patients (HR = 1.53, 95% CI: 0.89–2.18) using a fixed-effect model (I 2 = 35.1%, P = .214) (Fig. 4 ). 3.4.
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4e ) showed a strong trend towards decreased expression, which was similar to the findings with AR-upregulated pca-protein-coding genes (paired T test P value = 0.22, Supplementary Fig. 3e ) and the AR VIPER score (paired T test P value = 0.13, Supplementary Fig. 3f ) from the original studies 30 , suggesting that lineage plasticity due to treatment resistance may also alter the landscape of AR-regulated lncRNAs.
Figure 1 shows a strong trend of higher incidence of SD in men than women [125 cases (56%) vs. 94 cases (42%), P =0.237].
Further, there was a strong trend towards lower SUV peak (2.43 ± 0.42 vs 3.24 ± 1.25, P = 0.25) and SUV mean (2.30 ± 0.46 vs 2.87 ± 1.10, P = 0.45) for PFA compared to CBA patients, respectively.
Moreover, all three studies failed to show a reduction in clinically relevant cerebrovascular event rate with SentinelTM, although a strong trend was shown in the SENTINEL trial (5.6% vs. 9.1%, p = 0.25).
The EQ-VAS showed a strong trend in improvement from the pre-operative score (75.36 ± 17.86) over the recovery period, but did not reach statistical difference by Post-Op Week 12 (87 ± 9.53, p = 0.252) ( Figure 3 ). 3.2.
Importantly, this trend was observed in metastases, significantly for PACA-US (ρ = 0.42, p = 9.0E–4; Figure 6C ) and exhibiting a strong trend for PACA-CA (ρ = 0.29, p = 0.27), likely due to the limited number of metastases ( n = 16) in this cohort versus PACA-US ( n = 61).
Conversely, insomnia, bone and joint pain, hot flashes, worry about bone loss, vaginal dryness, emotional distress, decreased sex drive, and worry about ET interaction with other prescribed medications did not show a strong trend across time ( P = 0.29 to 1.00) and thus exercised relatively stable influences on nonadherence during the first 6 years of ET.
A strong trend for negative correlation of the same variables in the CG ( r = −0.36, p = 0.31) was observed, only corrupted by one participant (Figure 3A ).
Due to variability between patient samples, although there is a strong trend demonstrating the substantially better viability of non-frozen cells, it is not statistically significant (unpaired t -test, p = 0.3264).
optimal preparation showed a strong trend for reduced lesion detection (OR 0.94, CI: 0.87–1.01, p = 0.33; data not shown).
Patients with a partial (TRG2) histopathologic response after four cycles of neoadjuvant chemotherapy showed a strong trend toward longer OS and TSS [(OS: 17.2 ± 5.1 months versus 13.7 ± 4.6 months; p = 0.348); TSS (22.4 ± 4.3 months versus 13.7 ± 4.6 months; p = 0.232)], without reaching statistical significance (Fig. 4 C, D).
16 In contrast with these observations, the ARTE trial, which randomized 222 patients (111 to SAPT and 111 to DAPT), showed a strong trend toward a reduced 3-month mortality in the SAPT group (3.6% vs 6.3%, P = 0.37). 7 Further support comes from the CENTER2 (Cerebrovascular Events in Patients Undergoing Transcatheter Aortic Valve Implantation With Balloon-Expandable Valves vs Self-Expandable Valves) study, a pooled patient-level database from 10 clinical studies including a total of 23,562 transfemoral TAVR patients.
For the context test, while we did not find any main effects there was a strong trend for an effect of the demonstrator’s sex ( Fig 2B ; two-way ANOVA, OBSERVER’S SEX: F 1,27 = 0.6907, p = 0.4132; DEMONSTRATOR’S SEX: F 1,27 = 3.914, p = 0.0582; OBSERVER’S SEX x DEMONSTRATOR’S SEX: F 1,27 = 3.600, p = 0.0685; N = 7–8 per group).
Moreover, a strong trend in favor of DepoCyte ® in terms of time to neurological progression (78 versus 42 days; p > 0.5) and overall survival (99 versus 63 days; p > 0.5) was observed.
S4E ), although there was a strong trend (p = 0.508) toward elevated L-lactate production (Supplementary Fig.
When post-operative CEA was used as a categorical variable, a strong trend was observed between ≤5 and >5 ng/mL values and DFS, with the 3-year DFS rate of 86.6% and 75.5% in the ≤ 5 and > 5 ng/mL groups, respectively; P = 0.53.
There was a strong trend for an increased percent distance traveled in the center in the mice treated with 07/1 mAb ( p = 0.54); however, this did not reach significance (Fig. 1 b).
Fullness was significantly increased after consumption of both meals, ( F (1, 24) = 29.85, p < 0.001), but similar to hunger and desire to eat, there were no significant differences between meals, although a strong trend existed ( F (1, 24) = 0.19, p = 0.66, or meal*time, F (1, 24) = 3.48, p = 0.07). 4.
Neither mitochondrial distribution nor the number of mitochondria was significantly affected by hyperglycemia in the LHb ( Figures 2F – H ), although there was a strong trend for a decrease in the number of mitochondria in the STZ group at both 6- and 12-week endpoints (VEH 6-week = 1.00 ± 0.21, STZ 6-week = 0.68 ± 0.22, p = 0.67; VEH 12-week = 1.00 ± 0.16, STZ 12-week = 0.64 ± 0.19, p = 0.59; treatment X time: F (1,16) = 0.009, p = 0.92; effect of treatment: F (1,16) = 2.86, p = 0.1; effect of time: F (1,16) = 0.009, p = 0.92).
The form of folate also affected ambulatory activity as evidenced by a strong trend towards reduced activity that was mainly driven by the high MTHF form (Dose p = 0.7, Form p = 0.054, Dose×Form p = 0.09).
2014–2018, F (1,18) = 0.12, p < .74; however, a strong trend towards an increase in symbolic violent acts from the first to the second time period was evident, F (1,18) = 0.12, p < .74 (see Fig 3 ).
Although a strong trend of increase was shown for platelet rGSK‐3β(T/S9), the difference did not reach statistical significance between T2DM‐MCI and T2DM‐nMCI groups (GSK‐3β‐Total: p = 0.760; GSK‐3β: p = 0.237; rGSK‐3β: p = 0.122) (Figure 3a‐c ).
a strong trendgold
However, the interaction Face Presence by Morphosyntactic Correctness yielded a strong trend and almost reached statistical significance in the later interval of the component, being smaller in presence of the face (500–700: F (1,27) = 0.35; P = 0.85; η 2 = 0.00; 700–900 ms: F (1,27) = 3.9; P = 0.058; η 2 = 0.13).
Following cold exposure, both Ly6C + CCR2 + Cx3CR1 − and Ly6C + CCR2 + Cx3CR1 + populations increased in inguinal scWAT of female mice ( p = 0.0401, p = 0.0354 ), however, only the Ly6C + CCR2 + Cx3CR1 + population showed a strong trend for increase in males ( p = 0.9525 and p = 0.0566 ) (Fig. 4 c).