“a strong trend”

There was a strong trend toward graft infection as a risk factor for late mortality (hazard ratio, 1.99; 95% CI, 0.779- 5.00; P = .14).

The results showed a strong trend towards higher perfusion rates (~58% greater, p = 0.14), and significantly higher glucose uptake in LCC6 HER-2 (~2-fold greater; p = 0.025), relative to control tumours.

A strong trend towards increased collagen production was also noted after 2 Gy irradiation, albeit not statistically significant ( p = 0.147).

A strong trend toward increased 30-day mortality was found if pre-procedure serum albumin level was ≤30 g/L (30-day mortality OR, 7.43; p =0.148).

There is also a significant difference with SS metric and a strong trend in the differences with PTT (p = 0.149) and SM (p = 0.105) metrics between control and high functional stroke group, which suggest that the performance of able-bodied subjects in the trajectory tracking task tend to be more accurate (PTT), stable (PTT) and with better speed consistency (SM, SS) than high functional stroke subjects.

On the target gene protein expression level, STAT3-MB + UTMC-treated tumors exhibited a strong trend towards decreased expression of Bcl-xL (normalized by GAPDH) (36.9±25.7%) compared to the mutant control (94.5±50.1%, p <0.15).

Furthermore, the HDIVC group had a strong trend towards more ventilator-free days (13.1 in the HDIVC group vs 10.6 in the placebo group mean difference, 2.47, 95% CI −0.90–5.85, p = 0.15), ICU-free days to day 28 (10.7 in HDIVC group vs. 7.7, in the placebo group, p = 0.03), and more hospital-free days (22.6 in HDIVC group vs. 15.5, respectively, p = 0.04).

In a prospective study, vomiting was significantly more common among patients who experienced long-term failure compared with those who did not (12% vs 4%, p = 0.01), and retching showed a strong trend toward association (32% vs 18%, p = 0.15). 19 Wakeman and Hunter similarly reported that postoperative retching was a key predictor of early disruption. 20 , 21 Biomechanical studies help explain this vulnerability, showing that the bursting pressure of a fundoplication is approximately 250 mmHg, y

Young’s modulus showed a strong trend of reduction in treated scars, with 5/6 treated scars recording a lower YM than their matched vehicle treated scar (Fig. 8g , p = 0.15), suggesting PXS-6302 treated scars are more pliable than their placebo-treated controls.

In CMS3, we observed a strong trend toward longer survival in the cetuximab arm in RAS wt (HR 0.57; P = 0.15).

Furthermore, the HDIVC group had a strong trend towards more ventilator-free days (13.1 in the HDIVC group vs. 10.6 in the placebo group mean difference, 2.47, 95% CI − 0.90–5.85, p = 0.15), ICU-free days to day 28 (10.7 in the HDIVC group vs. 7.7, in the placebo group, p = 0.03), and more hospital-free days (22.6 in the HDIVC group vs. 15.5, respectively, p = 0.04).

A comparison of major hemorrhagic injury between those with normal INR values (INR = <1.3) and those in the therapeutic range (INR 2–3) showed a strong trend towards fewer complications in the group with therapeutic INRs (normal INR, 10.1% (209/2066); INR 2–3, 6.9% (15/218); odds ratio 0.65, 95% CI; 0.38, 1.13; p = 0.15).

Analysis of the TCR.strong metric in the Ipi-N cohort of patients showed increases in those with clinical responses (p = 0.0105) and a strong trend in patients from the Ipi-P group (p = 0.1531, Figure 7 C).

Although daltroban showed a strong trend toward DND reduction ( P < 0.159 compared with vehicle) with reduced brain microthrombi formation, WEB2086 did not lower DND incidence or microthrombi.

When melatonin was taken orally beforehand, there were no significant effects on LVEF, but there was a strong trend to promote LVEF (SMD: 0.60; 95% CI: −0.24 to 1.43; P = 0.16; and I 2 = 79.4%, Figure 4(b) ).

Total comorbidity impact on survival Comparison between patients with a singular comorbidity (n=18) to those with two or more (n=77) showed a strong trend towards decreased survival (p=.16, Figure 9 ).

The presence of bronchus sign significantly reduced the procedure time (β = -22.66, p = 0.008), and also showed a strong trend of improving diagnostic success (OR = 3.72, p = 0.161).

Interestingly however, SERCA2a expression demonstrated a strong trend (both p = 0.17) toward being reduced in KO atria tissue, providing evidence for a dysfunction like phenotype in the atria driven by genotype, consistent with echocardiography derived %FS data (Figure 3f ).

Finally, the median activity of FVIII showed a considerable increase in both patient cohorts (SI 235 [91-320] % and MI 197 [164-238] %, respectively) compared with the CO, but although a strong trend was identified between the SI and CO (108 [89-133] %; p = 0.17), no significant differences were detected.

There was also a strong trend for a reduced proportion of CD4+ cells (p = 0.17) while CD8 and B220+ cell proportion did not change.

4F ), while CD8+ staining showed significant increases with S-7 ( p = 0.0312) and a strong trend towards increase with Serp-1 ( p = 0.1734) treatment (Fig. 4G ).

When we analysed overall survival (OS) data, however, we found a strong trend between fumarate detection and poor outcome in Group 3 MB patients compared to no association in SHH patients ( p = 0.1793 versus p = 0.661, Fig. 7 a, b).

No significant interaction effect was found between interventions across five MFI‐20 subdomains during the trial ( p > .05), although a strong trend interaction effect was noted for reduced motivation toward creatine ameliorating this fatigue subdomain and placebo acting in the opposite direction ( p = .18).

The experimental intervention resulted in a significant elevation of brain total choline (tCho) levels at two locations (left and right paracentral grey matter) during the trial ( P ≤ 0.05); a strong trend for a non-significant increase was observed at the left frontal white matter, left parietal white matter, and right parietal mesial grey matter ( P ≤ 0.20).

Variables that did not show at least a strong trend ( P < 0.2) towards influencing the risk were not included in the later multivariable models.