In the present study, Kaplan–Meier analysis of PFS and OS revealed a strong trend for better prognosis for patients with high SPHK1 expression ( p = 0.107 and p = 0.124, Figs. 2 and 3 , respectively).
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Although the sample sizes are small for comparison, there was a strong trend toward superior OS in patients receiving resection ( P = .107).
Ki-67 positivity (≥5% nuclei staining) showed a strong trend towards earlier biochemical-recurrence following prostatectomy ( P = 0.107) ( Fig. 2C ) (analysis of the full set of 156 cases evaluable for Ki-67 reached statistical significance; data not shown).
In terms of hair breakage by week 8, there was a strong trend for the Study Product group to have less hair breakage than the Placebo group (−0.78 ± 20.720 vs 6.22 ± 18.036; P = .1085).
Given that there is less data per subject in this analysis, it is unsurprising that there is now only a strong trend to significance for positive LVD areas ( p = 0.11) and peaks ( p = 0.06), with no difference for negative LVD areas ( p = 0.28) and peaks ( p = 0.25; Table 3 ).
1 b, c) although there was a strong trend of 44% lower plasma apoE levels in NHW APOE ε4 homozygotes compared to ε4 non-carriers ( p = 0.110, Tukey HSD) (Fig. 1 c).
2.5 ± 0.8, p = 0.02) and a strong trend towards higher values of SUV max for CBA patients (6.8 ± 2.8 vs. 4.4 ± 1.5, p = 0.11).
Measures of connectivity were not significantly different between treatment groups, although a strong trend was detected (2‐way RM ANOVA; F [1,56] = 2.72, p = 0.11).
We confirmed that polg-1 expression shows a strong trend of remaining elevated up to 4 days post-exposure (p = 0.11) and returns to control levels of expression by 8 days post-exposure ( Fig. 1 F).
Moreover, there was a strong trend for the /ɹɑ/ deviants to elicit less low gamma activation than the /wɑ/ deviants over the left hemisphere during both the 50–100 ms ( F (1,14) = 2.899, p < 0.11, η 2 = 0.172) and 100–150 ms windows ( F (1,14) = 3.063, p < 0.10, η 2 = 0.180); no phoneme differences were noted over the right hemisphere.
Despite a strong trend towards lower levels in surviving patients became apparent, the difference again did not reach statistical significance (p = 0.113; Fig. 4B ).
However, we observed a strong trend showing an increase in freezing in the 6-month-old hM3Dq mice that was like remote recall (two-way ANOVA; interaction: F(1,41) = 2.618, p=0.1133; age: F(1,41) = 2.335, p=0.1342; group: F(1,41) = 5.763, p=0.0210; Tukey’s [group]: 6MO mCherry vs. hM3Dq, p=0.0590; 14MO mCherry vs. hM3Dq, p=0.9269) ( Figure 4di–ii ).
Age-stratified analysis demonstrated a strong trend toward better survival in pediatric recipients compared to adults for 5-year outcomes (HR = 0.54, 95 % CI: 0.23–1.24, p = 0.114), with pediatric recipients maintaining approximately 60 % survival compared to 45 % in adults ( Fig. 5 c).
Further analysis of the initial stimulation period revealed that while a statistically significant reduction was not yet achieved during the first X-ray pulse across all groups, a strong trend toward suppression was present exclusively in the experimental group ( p = 0.1164, paired t -test, Fig.
5.8 %, p = 0.02), and a strong trend towards reduction in 24-h all-cause mortality (17 % vs. 12.7 %, p = 0.12) when a 1:1:1 plasma: platelets: RBC ratio was used, compared to 1:1:2.
A Cox model interaction test of primary tumor sidedness and prior treatment arm for PFS 2 nd showed a strong trend for an interaction (P=0.12).
No difference in PFS was found (9.7 months in both arms, HR 1.071; 95%-CI 0.689–1.665, p = 0.76), but a strong trend about enhanced mOS in the experimental arm has been reported (35.7 months vs. 29.8 months; HR: 0.67; 95%-CI 0.41–1.11, p = 0.12) [ 14 ].
A strong trend ( p = 0.12) toward an increase in trunk LTM was demonstrated.
RPMI already showed expression of all three proteins, which were necessary for podocyte functionality, the addition of retinoic acid significantly increased the protein expression levels of nephrin ( p = 0.04), with fold changes ranging from 1.4 to 14.95, and a strong trend towards significance for synaptopodin ( p = 0.12) with fold changes ranging from 1.5 to 7.8 was observed ( Figure 2 a,b and Supplementary Figure S1j ).
9.7 months; P = .040) and a strong trend toward improved OS (91.1 vs. 39.1 months; P = .128).
This increase in thin spines appears to be principally located on basilar dendrites: there was a strong trend toward an increase in thin spines on basilar dendrites but no such effect on apical dendrites (apical: t 8 = 1.73, p=0.13; basilar: t 8 = 2.20, p=0.060; Figure 4—figure supplement 1G ).
A strong trend toward improved 5-year survival was also noted among the group with ideal and adequate placement as opposed to unacceptable placement (61% vs. 42%, p = 0.13).
Although a strong trend was visible, no statistically significant difference was observed when comparing both groups ( p = 0.137) ( Fig. 3A ).
In this subgroup, patients with low CXI showed a strong trend toward poorer survival (5.1 months vs. 12.0 months, log-rank p = 0.139, HR: 2.355, Supplementary Figure S1 ).
Although these results were statistically not significant, they revealed a strong trend ( p = .14).