“a strong trend”

The high-dose spironolactone cohort also showed a strong trend toward moderate hyponatremia by inverse probability of treatment-weighted Cox regression with propensity score adjustment on ITT (HR, 3.1; 95% CI, 0.9–10.9; P = .08) and CDC (HR, 2.1; 95% CI, 0.9–4.5; P = .07) analysis and exhibited a significantly shorter time to hyponatremia ( Figure A1 ).

A one-way ANOVA for treatment group on the density of Arc mRNA expression in PRL ( Figure 7B ) showed a strong trend (F 4,23 = 2.4, p = 0.08) towards significance.

Although not significant, children with LBW showed a trend of being smaller than children with NBW, with a strong trend of lower FM in the LBW group compared with the NBW group ( p = 0.08).

However, Bcl2-rescued group displayed a strong trend of mushroom spine enhancement in Grin1 f/f mice (Bcl2 vs GFP: p = 0.08, Figure 3Q ), but not in WT mice (Bcl2 vs GFP: p = 0.5, Figure 3L ), suggesting that NR1 KO GCs accounted for a portion of neurons rescued by Bcl2 and they had more mushroom spines than those dying of reasons other than genetic ablation of NMDARs.

In the PEPCAD-II trial, there was, in contrast to our findings, a strong trend towards lower rates of MACE in the DEB group compared to paclitaxel-eluting stent (9% versus 22%, respectively; p = 0.08). 21 However, in addition to being compared to first-generation DES, there were only 5 total deaths in the PEPCAD-II trial, suggesting again a population at lower overall risk th

In addition, after combining the protein treatments, a strong trend for an effect of the pooled PB and WP treatments compared with MDP treatment only was observed (0.69 kg; 95% CI: −0.08, 1.46 kg; P = 0.08) that was similar in magnitude to that shown for untrained young adults via an unadjusted meta-analysis ( 8 ).

Subsequent pairwise analysis showed that there was a strong trend for unilaterally 6-OHDA-lesioned rats to be more immobile in the mFST compared to normal rats ( p = 0.08).

While the data confirm that CSP is one of the major antigens recognized by malaria-immune B cells, they also show that other sporozoite-specific antigens are present and recognized by a significantly higher number of B cells; (b) the frequency of CSP-specific B cells is significantly higher in subjects protected by the RAS vaccine (p = 0.016, 2-sided T-test); (c) the frequency of sporozoite-specific B cells has a strong trend to be higher in protected subjects (p = 0.08, 2-sided T-test).

Though a strong trend was observed towards reduction ( P = 0.08 and 0.09, respectively), this did not reach significance (Figure 2F ).

A strong trend (P = 0.08) towards increase in insulin level was also observed at 60 minutes in CBX-treated lean rats, when compared to that of control lean rats ( Figure 9 ).

Letrozole also demonstrated a strong trend, despite the crossover, for improved OS (303 letrozole vs. 343 tamoxifen events; HR = 0.87; 95% CI, 0.75–1.02; P = 0.08).

Most recently, Cucchiara and colleagues [ 8 ] found significant higher prevalence of an incomplete circle of Willis in migraine with aura (71%) and a strong trend ( p = 0.08) in patients without aura (67%) compared to controls (51%).

There was also a strong trend towards reduced systolic strain in T2DM (21 %) compared to both control groups (23 % p = 0.08), suggesting these patients may be on the verge of developing systolic as well as diastolic impairment.

In Pfdhfr , only minor differences can be seen between the two cross sectional surveys where a strong trend for a decrease in the prevalence of the 108S wildtype is apparent (from 49.6% to 38.0%, χ 2 = 3.06, P = 0.080).

Consistent with this, Seahorse extracellular flux analysis revealed that LCN2 reduced basal respiration (showing a strong trend toward reduction; p < 0.08, Fig. 4G ) and significantly decreased ATP production (Fig. 4H ), whereas Slc22a17 knockdown blunted the effects (Fig. 4G, H ).

As reported in Table 5 , in LTLE decreased left lateralization in the frontal ROI was significantly correlated with better naming outcome 6 months after ATL for the Naming task (r = − 0.50, p < 0.05), and there was a strong trend for the VGen task (r = − 0.48, p = 0.08) and the Fluency task (r = − 0.45, p = 0.08).

Finally, there is a strong trend for the Semantic Fluency Test ( p = 0.080) with a post hoc showing a statistically significant difference between baseline and post-test conditions (Mean difference = -4.571; p -value = 0.013).

However, despite the small sample size, bacterial community composition differed by farm when using Bray–Curtis ( p = 0.03, PERMANOVA) ( Figure S3C ) and unweighted UniFrac ( p = 0.03, PERMANOVA) but was only a strong trend when using weighted UniFrac distances ( p = 0.08, PERMANOVA).

However, a strong trend toward a reduced CD8 + cell count in the ARDS population at the initial visit was observed (p = 0.08) ( Figures 3 C and 3D).

2 , C and D); however, there was a strong trend toward reduced basal cortisol levels in female BETA F 2 offspring ( P = 0.08).

The results were qualitatively very similar ( Supplementary Figure S2 ), with a strong trend toward an effect of the genotype by stimulation intensity interaction ( p = 0.08, F (1, 18) = 3.39, mixed-effect analysis; Supplementary Figure S2 ).

A strong trend (DeLong p = 0.08) was observed towards better endpoint identification performance of the HCM Risk-Kids Model compared to the ACC/AHA strategy.

Both male and female rats responded with reduced number of lever presses, and rewards earned, to a similar extent as, for rewards earned, there was no significant drug‐sex interaction: F(1,34) = 0.99, p > .05; a strong trend to an effect of sex F(1,34) = 5.72, p = .08; and a significant effect of drug: F(1,34) = 15.20, p < .0001.

Neither of the memory tests accounted for a significant amount of variance on its own (but both showed a strong trend: memory for numbers: t = 1.76, p = 0.08; and memory for words: t = 1.95, p = 0.06).

Post hoc comparisons revealed that the Vehicle control group showed a higher change in conditioned social bedding preference than each of the CPF exposed groups ( p < .05), and the difference between the NT and the CPF groups showed a strong trend towards statistical significance ( p = .08 for 2.5 mg/kg and p = .053 for 5 mg/kg) (Fig. 3 ).