“a strong trend”

However, when we evaluated MMP-9 and MMP-2 activity in EDL homogenate (EDL muscles have a similar fiber type composition to TA muscles) via gelatin zymography, we found a strong trend for IRI+BGP treatment to increase MMP-9 activity relative to VEH ( p = 0.08; Figure 4 J,N) whilst also significantly reducing MMP-2 activity compared to VEH and IRI treatments ( p < 0.05; Figure 4 K,N).

A strong trend (P = 0.08) towards increase in insulin level was also observed at 60 minutes in CBX-treated lean rats, when compared to that of control lean rats ( Figure 9 ).

Cognitive status significantly moderated the association between plasma biomarkers and ERC volume for both p-tau181 (β = −0.39, p = 0.04) and NfL (β = −0.44, p = 0.03), with a strong trend for GFAP (β = −0.46, p = 0.08).

There was also a strong trend evident between scene-related deactivations (S < rest) and scene oddity accuracy in the HC ROI ( r = 0.30, p = 0.08, 95% CI [−0.039, 0.606]; Figure 4C ); an association that was not evident for the face oddity condition (p = 0.20).

There were no correlations ( P > 0.05) between age, Hb, and LVEF with V̇O 2peak or other CPET variables, although Hb showed a strong trend with V̇O 2peak ( r = 0.38; P = 0.08).

In agreement with earlier reports, we observed lower phagosome maturation following FcR-mediated phagocytosis in HIV infected persons compared to HIV negative subjects, although the difference was not significant but rather a strong trend ( p = 0.08 at 10 min and p = 0.06 at 120 min).

A strong trend was also observed in the 12-week training group (p = 0.08) compared to their matched 12-week sedentary control.

In another model of human disease, we found significantly higher levels of Thbs1 mRNA and a strong trend ( P =0.08) towards higher levels of TSP-1 protein in whole-lung lysates from newborn calves with chronic hypoxia-induced PH ( Fig. 5d and Supplementary Fig. 27 ).

10 In 1995, the Non-Small-Cell Lung Cancer Collaborative Group (NSCLCCG) published a meta-analysis showing a strong trend in favor of adjuvant cisplatin-based chemotherapy (hazard ratio[HR], 0.87; 95% confidence interval [CI], 0.74–1.02; P = 0.08), with an absolute improvement in the 5-year survival rate of 5%.

This test revealed a strong trend suggesting that dropout rates were dependent on group assignment ( χ 2=5.14; P =.08).

STAT1 protein levels were unchanged at 2 hours and 6 hours, however at 24 hours a strong trend in increased protein production was detected in the stimulated cells ( Fig 3D , P = 0.08, + Bb 2 hours vs. + Bb 24 hours).

Significantly decreased levels of the MoAM associated chemokines CCL2 and CCL7 (21% and 69%, respectively) and a strong trend towards decreased total BALF macrophage counts (30% decrease on average, p = 0.08) in treated animals further corroborates the anti-inflammatory effect of the IRAK4 inhibitor ( Figures 8B, C ).

Serum ferritin was also significantly associated with transplant survival (p = 0.02), while the marrow iron stain showed a strong trend towards statistical significance (p = 0.08).

In the subgroup analysis, a strong trend toward a decrease in TLR (RR = 1.36, 95% CI 0.96–1.91, p = 0.08; I 2 = 0%, p = 0.56, Figure 4 ) was even noted in paclitaxel-eluting stent (PES) group, although this difference was not statistically significant compared to DCB.

Moreover, an interesting phenomenon was observed as a strong trend of better compliance took place in patients treated with triweekly cisplatin plus RT after 2008 (OR, 0.61; 95% CI, 0.35–1.07; P = .08; Fig. 4 ).

Letrozole also demonstrated a strong trend, despite the crossover, for improved OS (303 letrozole vs. 343 tamoxifen events; HR = 0.87; 95% CI, 0.75–1.02; P = 0.08).

There was also a strong trend ( p = 0.08) towards a reduction in the percentage of double-positive ICAM-1/VCAM-1 cells in ANXA1-treated HUVECs (Fig. 3e ).

While the primary outcome of major cardiovascular events failed to reach statistical significance, a strong trend towards fewer events was noted in the atorvastatin group (6.9 % vs. 9.9 %, p = 0.08).

In preliminary analysis of a group of 278 lung transplant patients at a single center, we have found a strong trend toward greater risk of severe BOS in those with HLA-DR15 + donors (p=0.08; Haynes, LD, Meyer, KC, Amir, A, Wilkes, DS, and Burlingham, WJ, manuscript in preparation).

While the inputs from other cortical subregions remain unchanged between genotypes a strong trend for the effect of mutant SOD1 was noticed by 2-way ANOVA in both rabies titer cohorts (LT: F1,120 = 3.07, p = 0.08; HT: F1,80 = 3.43, p = 0.07) (Fig. 4 A, D).

plantarum exhibited a strong trend of more transitions to the upper zone ( p = 0.08) and spent significantly more time in the upper portion of the tank ( p = 0.01) ( Fig. 4C–F ).

Again, there was a strong trend for an interaction between diet and sugar (F 1,26 = 3.320, P = 0.08) with no effect of time (F 1,26 = 1.741, P > 0.05).

Moreover, there was a strong trend for a larger ∆ with NO relative to PL ( p = 0.08).

Consistent with this, Seahorse extracellular flux analysis revealed that LCN2 reduced basal respiration (showing a strong trend toward reduction; p < 0.08, Fig. 4G ) and significantly decreased ATP production (Fig. 4H ), whereas Slc22a17 knockdown blunted the effects (Fig. 4G, H ).

In the patients receiving active treatment, this remained significant for mannitol (p=0.01) and showed a strong trend for FEV 1 (p=0.08).