“a strong trend”

Both WT and Tph1 (−/−) mice were able to learn the association between the stimulus light and reward (session effect: F (12,493) = 93.385; P<0.001) however there was a strong trend indicating that aged Tph1 (−/−) mice may acquire this association slower (age×genotype: F (36, 493) = 1.398; P = 0.06; Figure 3A ).

In the iliac artery, the atherogenic diet reduced EC 50 ( p < 0.05) and there was a strong trend for a reduction in AUC (17%, p = 0.06) compared to the normal diet ( Figure 1 C,D).

There was a strong trend towards decreased cardiac index in the SIT group compared to CON ( p = 0.06).

Noteworthy, we observed no cellular inflammatory response as shown by the Il‐6 gene expression (Figure 3f,k ) and release of IL‐6 (Figure 3g ) at sub‐lethal concentrations, although a strong trend ( P = 0.06) of IL‐6 release was observed under 10% CSE (Figure 3l ).

Even though the significance was lost in the fully adjusted model, a strong trend ( P = 0.06) for a positive association between serum DMA concentration and increased cIMT was still apparent.

There was, however, a strong trend (group × time effect, p = 0.06) for the MIPS group to improve peak anaerobic power.

There was a strong trend for greater AUC in Sham-HFD compared with Sham-Con ( p = 0.0603).

Subsequently, a strong trend suggestive of increased CD8+ T TD frequencies was observed only in PuPs compared to SN individuals ( p = 0.0603) ( Figure 4A ).

The expression of four genes of interest, normalised to internal controls, showed a strong trend in the expected direction for Il1b ( p = 0.0608) and a significant downregulation for Il6 ( p = 0.0340).

In the IL‐2 q4wks group, CSF Aβ42 levels improved significantly ( p = 0.045), with a strong trend toward stabilized CSF NfL levels ( p = 0.061).

However, a strong trend toward a higher cumulative incidence of death from HF/heart transplant (HT)/ventricular assist device ( p = 0.061) and of sudden cardiac death (SCD)/ventricular tachycardia (VT)/ventricular fibrillation (VF) ( p = 0.062) was observed in variant carriers compared with non-carriers.

In contrast, in our study we observed no difference in stage IV survival according to the mutational status but a strong trend (p = 0.061) for an impaired DMFS in BRAF mutant patients.

The raw differences between groups showed that telomere length was longer in meditators (Mn = 10.47; SD = 0.86) compared to controls (Mn = 9.87; SD = 0.94), without any statistical significance, but showing a strong trend (t = −1.94; df = 32; p = 0.061), with a moderately high ES (d = 0.67).

The vehicle-treated group demonstrates a strong trend towards the net loss of spines over the course of our study, reaching a near-significant level by 132 h (p = 0.061 for 0–132 h, see Table 2 ).

Moreover, there was a strong trend towards a decreased parenchymal pericyte density in the T2D-E group compared to the T2D-VH group (p = 0.061), and no difference was detected between non-T2D and T2D-E animals (Fig. 6 e).

Total band density for eNOS (using the non-phospho-discriminating antibody) showed an increase in the IHS group in outer medulla, with a strong trend ( p = 0.061) for cortex.

ALFF of the thalamus exhibited a strong trend toward a decrease in PBC patients relative to control subjects [F(1,28) = 3.80, p = 0.061], suggesting a potential reduction in the activity level of the thalamus.

Additionally, neither GM ( p GM = 0.892) nor sex ( p Sex = 0.951) affected time spent in either chamber of the social preference test overall; however, a post hoc analysis using paired T tests revealed a strong trend toward GM High males exhibiting greater asocial behavior ( p = .061), spending more time in the object zone relative to the stranger zone.

Mediastinal (N2) station sampling showed a strong trend toward more thorough dissection in the uRATS group (median 4 stations [IQR 3–4] vs. 3 [IQR 2–3]; p = 0.061; Figure 5 C).

The effect of task load was significant for the novelty P3a amplitude, F (1,56) = 5.80, p = 0.019, η 2 = 0.09, and there was a strong trend towards significance for the RON, F (1,56) = 3.66, p = 0.061, η 2 = 0.06.

However, traumatic experiences during pushback significantly added to the prediction of depression, accounting for an additional 3.7% of the variance [ F (1,126) = 6 .294, p = .013] over and above traumatic experiences in transit, showed a strong trend-level effect in the prediction of anxiety [ R 2 = .023, F (1,126) = 3 .561, p = .061], and had no incremental value in prediction of PTSD [ R 2 = .008, F (1,126) = 1 .191, p = .277], thus marginally accounting for 2.4% of the variance in overall psychological vulnerability [ F (1,126) = 3 .905, p = .050].

Effect of GPR37L1KO on the Corticosterone Level after PAT A three-way ANOVA on the level of circulating corticosterone revealed a significant effect of genotype x sex [F (1,54) = 4.04, p = 0.049; Figure 6 ] and a strong trend towards significant effect of genotype [F (1,54) = 3.66, p = 0.061; Figure 6 ], age x sex [F (1,54) = 3.65, p = 0.061; Figure 6 ] with no significant effect observed for other factors ( Figure 6 ).

There was a strong trend for greater expression of CPT-1α in the HV-HPMC group compared to the obese control (p=0.061).

Rats injected with the highest (20 mg/kg) dose of KET displayed a strong trend ( p = 0.061) towards a lower proportion of lose–shift behaviors following true negative feedback compared to the control group (statistically significant main effect of treatment ( F (3,25) = 3898, p = 0.021, Fig. 2 b), regardless of the time (1, 24, or 48 h) after injection (non-significant treatment × test interaction ( F (6,50) = 1955, NS).

Association of PITX3 DNA methylation with survival Higher PITX3 DNA methylation analyzed as continuous variable showed a strong trend towards poorer overall survival in the training cohort (Hazard ratio (HR) = 1.01, [95% confidence interval (95%CI) 1.00–1.02], p = 0.061).