“a strong trend”

These analyses, which should be interpreted with caution in the absence of an overall significant effect, suggested a specific pattern: Delta TM D to E was reduced in the pre-PRF group compared to the HC group, with a strong trend ( p = 0.016, uncorrected for multiple comparisons; Fig. 5 a, Table 4 ).

The core diagnostic item concerning feeling anxious, worried, or nervous (ANXTY) showed a strong trend level differences ( p = .017, two-sided t -test) with a normalized mean difference of 3.5, though this item was not significant after Bonferroni correction.

NK-cell counts were in general more similar between the conditions but a strong trend towards increased NK-cell numbers in malignant tissue compared to control tissue was found ( p = 0.017).

Further, relative to APOE ε4 + ve/ KIBRA T carriers, the APOE ε4 + ve/ KIBRA non-T carrier group showed a nominally significantly greater rate of decline on the verbal episodic memory composite, however after FDR correction this remained only a strong trend (p = 0.018, q = 0.055) over six years (Fig. 2 , Table 3 ).

Updated results of the NCCTG N9831 study demonstrated a strong trend for an absolute benefit in DFS of 4.4% at 5 years with concomitant trastuzumab relative to sequential administration ( P = 0.019).

Excluding large predatory fish reduced isopod abundance by 46%, although differences were not statistically significant they showed a strong trend (Table 1 ; P = 0.019).

When evaluating individual cardiovascular risk factors, APOEε4+ subjects showed a strong trend toward a negative correlation between systolic BP and CP calcification (rho = −0.38, p = 0.02 uncorrected; p = 0.06 after Bonferroni correction).

In contrast, consistent with our hypothesis, the NR2B overexpression LMAN group exhibited dramatically lower group mean scores of consistency and stereotopy, and a strong trend for linearity (significant with the outlier Purple364 removed, p = 0.02, paired Wilcoxon signed rank test; Fig. 6a–c ).

Comparing Pk1a maximum power across genotypes revealed a strong trend supporting the bootstrapped spectrum results (Fig. 6r ; uncorrected p -value = 0.02), with no apparent difference in Pk1b maximum power (Fig. 6t ) nor the center frequency of either subpeak (Fig. 6q, s ).

There was a strong trend toward increasing arginase I level in pancreatic cancer, which did not reach statistical significance ( P = 0.020).

The only other substantial relationship was with CCNE1 levels that at baseline showed a strong trend to association with no achievement of CCCA for letrozole alone ( P = 0.02) but not for letrozole+palbociclib (Supplementary Fig.

Results showed a strong trend toward improved survival [hazard ratio (HR) 0.60, p = 0.02) in patients who received MVAC. 6 Because of the high incidence of adverse effects such as myelosuppression in patients taking MVAC, dose-dense MVAC (ddMVAC) was introduced which delivered the drug in two weekly cycles with growth factor support to abrogate this side effect. ddMVAC was well tolerated, with a ypT0 rate of 38% in one trial which included node-positive patients. 7 Numerous other trials were conducted in this space over the decades, some of which we have summarized below.

Interestingly, despite treating tumors of heterogenous sizes (right bigger or smaller than left) (Figure 5 b), the biofluorescence was systematically higher on the treated side at all timepoints (Figure 6 b), a strong trend that was detected by two-way ANOVA testing (effect of side, all p<0.02).

There was a strong trend for associations between reduced motor (β=-7.88, [CI=-14.55, -1.21], p=0.02) scores most notably in gross motor (β=1.76, [CI=-3.10, -.43], p=0.01) scores.

A strong trend was seen for increasing systolic BP levels (OR 1.01 per 1mmHg, 95%CI 1.00–1.03, p = 0.02).

However, these differences did not withstand post-hoc comparisons with a Bonferroni-corrected level of significance of 0.01, but showed a strong trend towards significance on the first ( p = 0.02, connection to EEG-recording system in the test group) and the last day ( p = 0.012, PET measurement in the test group) of the experiment. 3.3.2.

On this basis, there was a strong trend for a greater percentage of “past-infected” koalas (87.3%) to be DAB*10-positive than “healthy” koalas (60.0%) ( p = 0.021, Table 1 ).

In a limited subsample (n = 20), REPs suggested a strong trend toward faster apical closure ( P = .021), with 85.7% of REP cases achieving closure within 12 to 18 months compared to 23.1% of APEX cases.

While deficiency of FLOT2 led to a significant reduction of adhesion to HS-5 stromal cells, there was a strong trend toward restoration of adhesion when sh FLOT2 + K562 cells were treated with ML141 ( P = .0216) ( Figure 7G ).

After a median of 3.9 years of follow-up, a strong trend towards increased 5-year DFS was noted with concurrent trastuzumab and paclitaxel relative to sequential administration (HR 0.77, 99.9 % CI 0.53−1.11; p = 0.0216), but the p value did not cross the prespecified O’Brien–Fleming boundary for the interim analysis [ 17 ].

Contrary to expectation, the definitive analysis showed a strong trend of density decrease away from the trails for this species (Jonckheere-Terpstra Test, Z = -2.021, p = 0.022, n = 1390 plots).

Although both of the groups improved in accuracy of naming significantly in each consecutive testing point, there was only a strong trend in E group toward a significant increase in naming 15 weeks after rTMS treatment compared with C group ( U = 20, P = 0.024), but the differences were not significant after correction for multiple comparisons.

Within this subgroup, GLS demonstrated a strong trend of negative correlation with several myocardial injury markers: a perfect negative correlation with CK-MB (rs = −1.000, p = 0.025), and negative correlations with hs-cTnI (rs = −0.700) and NT-proBNP (rs = −0.500).

An interim analysis of overall survival (OS) revealed a HR of 0.77 (95% CI 0.61–0.97) indicating a strong trend ( p = 0.0257) for treatment with E-L/d versus L/d [ Dimopoulos, 2015 ].

15 An interim overall survival (OS) analysis demonstrated a strong trend in favor of ELd (HR 0.77; 95% CI 0.61, 0.97; P = 0.0257), in which there was a clear separation in the tail end of the Kaplan–Meier curves ( Figure 5 ). 15 Median (95% CI) OS was 43.7 months (40.3, not estimable (NE)) in the ELd arm and 39.6 months (33.3, NE) in the Ld arm. 15 The 4‐year PFS data