12 As with the monotherapy analysis, despite the crossover of patients from tamoxifen to letrozole, there was a significant benefit of letrozole over tamoxifen in DFS (585 vs 664 events, Table 1 ), TTR (368 vs 441 events, HR 0.82; 95% CI: 0.71–0.94; P = 0.004), and TTDR (287 vs 357 events, Table 1 ), and a strong trend in OS favoring letrozole (330 vs 374 events, Table 1 ).
Interestingly, we observed a strong trend towards higher suPAR levels in patients with a relevant uPAR expression, though statistical significance was not reached ( p = 0.082, Fig.
Indeed, a strong trend toward decreasing WSS is seen as a function of the indexed RPA radius cubed (Figure 6 b), which corresponds to the idealized pipe flow relationship between flow and diameter (i.e.
There is a strong trend for an independent association between metabolic syndrome patients with high blood pressure and glucose levels.
Their presence in a pro-proliferation in vitro environment did not lead to significant effects on NSPCs, apart from a strong trend for increase in Olig2+ cells.
There was also a strong trend for a current or previous history of TB to be associated with eye disease (Table 1 ).
Our data demonstrated a strong trend away from muscle atrophy markers to markers of muscle growth after 1 year of therapy.
In recent years, there has been a strong trend towards less invasive treatment of EPN.
This is indeed a strong trend, with 118 out of 127 drugs having a higher proportion of correctly predicted sensitive cell lines using the multi-gene markers.
Figure 6 show that there is a strong trend for SRT at rest being slower (about 20%) than response time when subjects are engaged in a complex motor task such as walking.
Interestingly, whereas overexpression of TAOK1 Leu167Arg and TAOK1 Leu315phe revealed a stronger migration deficit compared to TAOK1 WT , TAOK1 Leu548Pro showed normal migration compared to the empty vector condition and a strong trend toward improved migration compared to TAOK1 WT (Figure 4 , TAOK1 Leu167Arg vs.
Linnet Masese (University of Nairobi) found significantly higher rates of 100% condom use after ART began and a strong trend toward abstinence or having only one sex partner during ART.
A large positive or negative value of the test statistic indicates a strong trend in the positive or negative direction, respectively.
In line with the PLATO trial [ 16 ], we observed a strong trend towards higher levels of uric acid and a greater incidence of hyperuricemia in ACS patients receiving ticagrelor as compared with prasugrel-treated patients.
In the NAVIGATE ESUS trial, about two-thirds of carotid plaques were present in the carotid artery ipsilateral to the index stroke, showing a strong trend of a higher risk of recurrent ischemic stroke [ 39 ].
Strikingly, Tif1b -deficient HSCs showed a strong trend of ectopic expression of nonhematopoietic genes.
Not surprisingly, there has thus been a strong trend toward single-sport specialization among baseball players, with many players only playing baseball, year-round, starting at a young age.
Additionally, ER negativity showed a strong trend as a risk factor of intraoperative positive margin.
In the persistent symptoms-type group, ensemble classifiers did not show a strong trend in classification accuracy.
The lower overall survival probability of patients with low miR-9 expression that also tends to have a more severe pathological grade suggests a strong trend towards prognostic significance.
While CCL19 / C7 / APOE hi fibroblasts showed a strong trend to SSc fibroblasts which differed from CCL19 + fibroblasts of HC.
Both groups’ responded similarly to treatment so the results were pooled. Statistically significant increases in Box and Block score were seen on the treated side with a strong trend seen in the reduction in the time to perform the 9-HPT.
We found a strong trend toward worsened foot process effacement, though not reaching statistical significance, in the pGR KO mice treated with both protamine sulfate and with heparin rescue compared to the control mice under similar conditions.
Total JNK levels were not significantly different proximal or distal to injury site in jip3 nl7 mutants ( Figure 4F–4I, 4K ), though there was a strong trend towards decreased levels of the tJNK anterograde pool (proximal to the injury site) in jip3 nl7 mutants.
Historically, there has been a strong trend toward standardizing conditions in animal experiments, both in biomedical research and drug development, with the aim of enhancing reproducibility, minimizing biological variability, and ensuring regulatory compliance.