This shift in research priorities reflects a clear transition from fundamental molecular studies (e.g., “lipid rafts” and “signal transduction”) to disease-specific applications (e.g., “Hippo pathway” and “therapy”), demonstrating a strong trend toward translational and clinical research.
Furthermore, silica exposure was associated with worse SSc outcomes in these patients such as younger age at SSc diagnosis and a strong trend toward higher risk of dcSSc, ATA antibodies, more severe GI disease, ILD, and mortality.
The baseline serum LDH was also significantly correlated with length of stay (r = 0.43 p < 0.001). In univariate analysis, baseline serum LDH demonstrated a strong trend of association with increased risk of persistent chest radiograph abnormality but failed to reach statistical significance Hazard Ratio (HR) 1.001, 95% Confidence Interval [95%CI] (1.000–1.005) p = 0.078).
Yet there was a strong trend to less MI for patients receiving amlodipine compared with those randomized to placebo or irbesartan.
Overall, Québécois speakers were rated as producing stronger (i.e., more prototypical) complaints than French speakers, and there was a strong trend for Québécois listeners to recognize complaining prosody better when produced by other Québécois speakers.
In the absence of COMMD10, Ly6C hi monocytes exhibited a strong trend toward increased transcription of Il1b and significantly increased secretion of IL-1β in response to LPS (Figure 3I ).
Although our study has sample size limitations, we cautiously speculate that there is a strong trend towards alterations in processes such as energy metabolism, ribosomal protein translation, redox homeostasis, and cell survival/cell death in the brainstem of HETs, which is corroborated by our transcriptomic and metabolomic data.
Finally, meta-regression showed a strong trend of linear relationship between AAA growth rate and aneurysm diameter.
There was a strong trend towards a shorter time from admission to oral intake in the separated group with a median of 22.0 [2–39] days, compared to the non-separated with a median of 137.0 [102–148] days ( p = 0.050).
The benefit of nivolumab was seen in stage 3 disease (HR: 0.65, 0.52–0.83), with a strong trend toward improvement in resected stage 4 patients (HR: 0.70, 0.45–1.10).
We observed a strong trend toward positive association in subjects with heavy prescription opioids or benzodiazepines use (OR 1.6; 95 % CI 1.0-2.6).
While the V / F from the non-compartmental analysis, and the rate of absorption ( k a ), central and peripheral volumes ( V 2 / F and V 3 / F ) from compartmental analyses were generally comparable from low to high doses, there were a strong trend towards decreasing clearance (both distribution and elimination) with increasing doses.
The significance was at p = 0.0748, which suggested a strong trend that VitDBP could be a predictive biomarker of tooth movement.
The mutants exhibited a strong trend towards increases in short-chain glucosinolates accompanied by reductions in long-chain aliphatic glucosinolates (Tables 1 , 2 ).
CD34, while not reaching statistical significance ( p = 0.0714), showed a strong trend toward HCC-specific expression and remains diagnostically useful, especially in combination with other markers [ 54 , 55 ].
Although there is a strong trend towards integrating the data from various genetic studies and their related biological information into a comprehensive resource for many complex diseases, we have been unable to find such an effort for schizophrenia or any other psychiatric disorder yet.
Secondly, whenever this first stage showed a significant correlation or a strong trend for an activated region (e.g. striatum and amygdala), we performed a whole-brain multiple regression analysis on the contrast image of interest using the relevant questionnaire scores (e.g.
Treatment with FCM was associated with a strong trend towards an increase in eGFR at week 4 and 12, and a significant increase at week 24 with the following treatment effects: at week 4, 2.11 ± 1.21 ( P = 0.082); at week 12, 2.41 ± 1.33 ( P = 0.070); and at week 24, 2.98 ± 1.44 mL/min/1.73 m 2 ( P = 0.039) ( Figure 1 ).
18 Interestingly, the monofilament test of A δ and A β fibers 53 that was conducted as part of the MNSI evaluation showed a strong trend toward improvement in sensation at 6 months with continued improvements at 9 months.
2 Discussion The sum of the literature supports a strong trend in gender differences in dietary habits.
Better PS (HR = 0.043, 95% CI 0.014-0.136, P < 0.001) was independently associated with longer BM-related OS in multivariable analysis carried out for the ALK-BPI variables, whereas sex (HR = 0.61, 95% CI 0.35-1.06, P = 0.082) and primary brain metastatic disease (HR = 0.59, 95% CI 0.33-1.07, P = 0.084) showed a strong trend towards longer OS.
The results of our recent trial suggested that PWD in the Tai Chi group, relative to a usual care control group, at 6-month follow-up had significantly greater scores for quality of life, and a strong trend for a reduction in falls [ 19 ].
[ 10 ] investigated the effect of chronic oral foci on neutropenia and fever duration among 63 leukaemia and autologous HCT patients and showed a strong trend for a longer duration of neutropenia and fever in patients with chronic oral foci of infection [ 10 ].
Among them, multihybrid nanomaterials of TMHs have become a strong trend of exploration because of the existence of synergistic effect, superior chemical composition controllability, outstanding redox activity and excellent anion exchange performance.
Clinical effectiveness Repeated measures ANOVA at every assessment of the clinical trial revealed a significant time effect in most of the scales that assessed the body activities (the Wolf Motor Function Test, the Box and Blocks Test, and the Nine Hole Peg Test) and in the participation, and a strong trend towards significance in the Fugl-Meyer Assessment Scale (Table 1 ).