Bonomo Despite similar bacterial densities, diabetic but not nondiabetic mice experienced hypothermia, severe metabolic acidemia (low blood pH, low serum bicarbonate, and high base deficit), and markedly higher serum levels of interleukin-1β (IL-1β), IL-10, and tumor necrosis factor (TNF) than nondiabetic mice ( P < 0.05 for all comparisons), plus a strong trend toward higher levels of IL-6 ( P = 0.05) ( Fig. 2A and B ).
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Pooled analysis showed a strong trend toward reducing mortality risk in the OPCABG group (odds ratio: 0.75, 95% confidence interval: 0.56–1.00, p = .05).
Among the investigated biomarkers, only VCAM-1 ( p < 0.001) was significantly elevated in non-survivors, while no significant differences were observed for sST2 but a strong trend toward a statistical significance was evident for TnI ( p = 0.05, Table 2 ).
As shown in Fig 6 , simvastatin induced a significant decrease in -HAD activity in the EDL Sim 60 and Sim 80 groups ( Fig 6C ), with a strong trend (p = 0.05, main effect) for a decrease in the PLT Sim 60 and Sim 80 groups ( Fig 6B ).
When markers between these two survival groups were compared, we found that tumors associated with poor survival had a strong trend towards having higher total c-MET level compared to those with better survival ( p = 0.05), resonating previous report showing c-MET to be frequently overexpressed and represents an independent poor prognostic factor in resected PDAC patients [ 18 , 19 ].
76 NC-fed mice also exhibited a strong trend (bicor = −0.46, p = 0.05), suggesting that liver-kidney axis controls circulating concentrations of sebacate.
In the insoluble fraction, APP/PS1 mice show an increased concentration of Aβ 1–42 ( W = 16, p = .03) compared with their control mice, whereas for 3xTg there was a strong trend toward an increase ( W = 63, p = .05) compared with their controls (Figure 2B ).
However, normalized chamber variances of all experiments were within the same range (−0.4 < ∆ ab < 0.4), with a strong trend of LAB experiments being slightly more variable compared to field experiments ( p = 0.05).
There was a strong trend towards increased LPS-induced monocyte TF-specific MFI in patients with clinically significant arthropathy (6.8 ± 3.4 vs. 5.0 ± 2.5 AU; P = 0.05), while no differences were observed with regard to hs-CRP serum levels, whole-blood leukocytes and MV TF PCA.
The relative change of IOP for the 20G vitrectomized eyes showed a strong trend towards a significantly larger IOP decrease (mean ± SD of ΔIOPc: -0.59 ± 0.31 mmHg; P = 0.05).
There was a strong trend to a decrease in epigenetic age acceleration in female participants with the novel InflammAge clock ( p = 0.05, Suppl.
These included female sex (OR 1.31, 95% CI 1.07–1.60, p = 0.001), previous CABG (OR 1.6, 95% CI 1.18–2.17, p = 0.03) and atrial fibrillation (OR 1.84, 95% CI 1.47–2.29, p < 0.001) Patients with renal dysfunction were also at increased risk of readmission with a strong trend towards significance (OR 1.40, 95% CI 1.00 to 1.96, p = 0.05).
In addition, a strong trend for reduced volume and cortical thickness was observed for the ERC in the BD patients and the PRC in AD patients (0.005≤ p ≤0.05; Table 3 ).
The absence of a link between male size and brood size remained, although we detected a strong trend for the secondary male during the model selection process (p-value = 0.050; S10 Table in S5 File ).
Expression increases in miR-186 from post- to 60 min post-exercise (fold change = 1.58, P <0.001) paralleled a significant upregulation of SIRT6 mRNA (fold change = 1.66, P <0.05), a significant downregulation of TERF2IP mRNA (fold change = 0.54, P <0.01) and a strong trend towards significance for RAD50 (fold change = 0.76, P = 0.05).
Common force mechanical properties also displayed a significant time x group interaction in patellar tendon stiffness and a strong trend towards interaction in Young’s modulus ( p = 0.05) (Fig. 4 ).
However, there was a strong trend for mean BVPamp [ t (16) = −2.119; p = 0.050; effect size d = 0.51], which was lower during paraphrasing than during taking notes.
[16] In a Japanese trial that used low-dose (15 mg once daily) rivaroxaban (mean age of study population, 71 years), there was a strong trend for a reduction in the rate of stroke/systemic embolism with low dose rivaroxaban vs. warfarin (HR = 0.49; P = 0.050).
Treatment with mTOR inhibitor PP242 also displayed a significantly improved BBB score over the course of 6, 7, and 8 weeks ( p = 0.042, p = 0.047, and p = 0.025), and there was a strong trend ( p = 0.05–0.1) from 1–5 weeks after SCI.
3 D, left), there was a strong trend (P = 0.05) for mtH 2 O 2 to be higher in the presence of submaximal (100 μM) ADP following HFD ( Fig. 3 D, right).
There was a strong trend ( P = 0.05) for an improvement in whole-body insulin sensitivity (HOMA) ( Table 1 ), a finding supported by a reduction in the area under the curve during a 2-h OGTT ( Fig. 1 A and B ).
While no significant correlation between CAG-repeat length and absolute LQ was observed (r = −0.11; p = 0.31; polyserial correlation coeffient: −0.11), a strong trend was recognizable for a correlation between CAG-repeat length and LQ (r = −0.22; p = 0.05; polyserial correlation coeffient: r:−0.22), indicating that in homozygous women longer CAG-repeats had a tendency to be related with stronger left-handedness ( Fig. 3 ).
Notably, there was a strong trend for correlation with low PLT count as compared to patients without PL (P = 0.05).
In the logistic regression analysis these immunosuppressive treatments demonstrated a strong trend toward successful bridging with OR of 11.2 (95 % CI 1.00–125.7, p = 0.050) ( Fig. 5 ).
Multivariable linear regression Satisfaction with surgery In model 1, we found a lower postoperative satisfaction with a higher postoperative angle (β=−0.91 per degree, 95 % CI −1.55 to –0.27, p=0.007), higher postoperative diplopia (β=−0.23 per unit score, 95 % CI −0.43 to –0.02, p=0.03) and a strong trend with higher levels of anxiety (β=−1.85 per unit score, 95 % CI −3.74 to 0.04, p=0.05).