In the logistic regression analysis these immunosuppressive treatments demonstrated a strong trend toward successful bridging with OR of 11.2 (95 % CI 1.00–125.7, p = 0.050) ( Fig. 5 ).
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In addition, a strong trend in increased expression of HO-1 could be observed ( Fig 4B , p = 0.05) and the expression of NQO1 was elevated in response to shear stress ( Fig 4C , p = 0.004).
Multivariable linear regression Satisfaction with surgery In model 1, we found a lower postoperative satisfaction with a higher postoperative angle (β=−0.91 per degree, 95 % CI −1.55 to –0.27, p=0.007), higher postoperative diplopia (β=−0.23 per unit score, 95 % CI −0.43 to –0.02, p=0.03) and a strong trend with higher levels of anxiety (β=−1.85 per unit score, 95 % CI −3.74 to 0.04, p=0.05).
For the variant counts (B), there was a significant reduction in the long ccfDNA fraction compared to the medium ccfDNA fraction and a strong trend to have fewer counts than the short ccfDNA fraction. *P<0.05, **P<0.01, ***P<0.001.
These included female sex (OR 1.31, 95% CI 1.07–1.60, p = 0.001), previous CABG (OR 1.6, 95% CI 1.18–2.17, p = 0.03) and atrial fibrillation (OR 1.84, 95% CI 1.47–2.29, p < 0.001) Patients with renal dysfunction were also at increased risk of readmission with a strong trend towards significance (OR 1.40, 95% CI 1.00 to 1.96, p = 0.05).
Expression increases in miR-186 from post- to 60 min post-exercise (fold change = 1.58, P <0.001) paralleled a significant upregulation of SIRT6 mRNA (fold change = 1.66, P <0.05), a significant downregulation of TERF2IP mRNA (fold change = 0.54, P <0.01) and a strong trend towards significance for RAD50 (fold change = 0.76, P = 0.05).
Results G‐gradient, g‐level and duration Significant changes were observed in all measured cardiovascular variables except MAP where there was a strong trend for time (i.e. centrifugation) (Table 3 ; P < 0.05).
Among SHR and SE criteria NYHA 3–4, contralateral occlusions and intraluminal thrombus were significant determinants and MI < 4 weeks before CEA showed a strong trend ( p = 0.05).
The group effect in right anterior insula remained significant or showed a strong trend when controlling for either psychopathic traits ( p = .05, svc) or CU traits ( p < .05, svc).
Notably, the delivery of RNF5 was significantly increased in APOE3 (1.15 ± 0.06 fold, mean ± SE, P = 0.0295) with APOE4 iBECs demonstrating a strong trend toward an increase in RNF5 delivery (1.26 ± 0.12 fold, mean ± SE, P = 0.0501) when treated with FUS +MB as compared to UT (Figure 3 G).
In probe trials 1 and 2, performed at the end of hidden trial days 1 and 2, only sham mice for each of the genotypes showed preference for the target quadrant; a strong trend ( p = 0.0501) was observed in probe trial 2 for brain-injured syk f/f MRP8-cre + mice ( Supplemental Fig. 7B , C ).
A significant increase in abundance of the genus Bifidobacterium (p = 0.0001) and family Lachnospiraceae (p = 0.0301) and a strong trend of decrease in the bacterial genus Bacteroides (p = 0.0501) were seen after supplementation of vitamin C ( Figure 3 A–C).
Of note, when investigating NDMM patients separately, we observed a strong trend towards higher CD8 + TEMRAs (p = 0.05017) as well as elevated IL-8 levels (p = 0.05036) in patients developing SI ( Supplementary Figure 2 ).
A strong trend towards an increased ratio between vascular and tumor area [3.6% (2.9–4.6) versus 2.7% (2.4–3.4), respectively, P =0.0503; Fig. 2 C] was seen in NS/CT-2A tumors compared to ML/CT-2A tumors.
In the analysis of hippocampal volumes, we failed to reject the null hypothesis, but see a strong trend with p = 0.0503.
However, rating of reactivity phenotype (larger cell bodies, prominent processes) by a blinded observer indicated a strong trend to increased microgliosis in intensively trained transgenic mice (Fig. 4c , p = 0.0503).
56%), with an adverse HR for OS (HR, 3.94; CI, 1.00–1.55) and a strong trend for a lower survival advantage by log-rank analysis (P = 0.0503; Fig. 4 c ).
However, the combined adjuvant therapy showed a strong trend towards improved weight gain at 42 hpi compared to CRO monotherapy ( p = 0.0503).
Furthermore, eosinophil numbers were decreased in OVA/LPS/GC compared to OVA/LPS, although this was a strong trend (p = 0.0504), this decrease was not significant.
Two-way ANOVA revealed a strong trend in the main effect for sex ( F (1,28) = 4.182, p = 0.0504, NS) in the total dentate gyrus.
Notably, incubated rats did not differ from non-incubated rats on AD1 pressing ( p < 0.1411) and while non-incubated rats did not significantly reduce lever pressing between AD1 and AD8, there was a strong trend for significance ( p < 0.0504).
Interestingly, there was a significant negative correlation of MMP2 mRNA expression and LVAD support duration ( P = 0.038; r = 0.4424; Figure 6 A ) as well as a strong trend to a negative correlation between TGFβ mRNA expression and LVAD support duration ( P = 0.0504; r = −0.3077; Figure 6 B ).
Elevated Plus Maze Activity In pair-housed males, a Drug ∗ Age ANOVA revealed a strong trend toward an interaction of drug treatment and age on time spent in the open arms of the EPM following acute cannabinoid pretreatment [ F (3,67) = 2.73, p = 0.0505].
Finally, patients who underwent surgery with combined anterior-posterior approach had a strong trend toward greater local recurrence compared with patients treated by posterior approach only (45.6% vs 35.2%, P = .0505).
There was a strong trend (Newman–Keuls test, P = 0.0505) towards higher II at S4 (pre-adult) compared to S3 in females, both sexes had significantly lower II at S5 (48 h in fw) than S4 and lastly females but not males had significantly lower (Newman–Keuls test, P < 0.05) II at S6 compared to S5.