“a significant trend”

pasteri ) because they had a high relative abundance and the changes were significant or showed a significant trend.

A study showed that the benefit of lower diastolic blood pressure is limited to the range of 70–85 mmHg with a significant trend of 60–65 mmHg.

Additionally, there was a significant trend for interaction between smoking - categorized as never, former, current smokers - and Tregs in Cox regression analyses on MI (P interaction = 0.045), but not stroke.

The results showed that the dispersion tendency of the three groups was weaker at baseline (T0); the C + CR group and H group had a significant trend of separation at the time point of 3 months (T1).

Trend tests revealed a significant trend towards decreased mortality risk with escalating levels of PA ( p for trend = 0.0003).

Plasma PLP concentrations were lower with increasing age for both males and females ( P -trend < 0.001); however, this was most pronounced in males ( Figure 2 A ), whereas a significant trend for better riboflavin status (indicated by lower EGRac values) was observed in older compared with younger adults in both males and females ( P -trend < 0.001) ( Figure 2B ).

The Cochran Armitage trend test was employed to assess for a significant trend among increasing values of this categorical variable.

Concerning age, our results indicate a significant trend towards decreases in 25(OH)D levels with age, in line with previous reports [ 58 , 59 ].

Indeed, an exhaustive meta-analysis of the literature in this area suggested a significant trend for the evolution of viruses towards promoting these transmission-enhancing changes in plants [ 4 ].

As noted in Fig 2A , sunitinib and pazopanib were the most frequently used first-line therapies throughout the study period, and a significant trend toward increasing use of pazopanib and decreasing use of sunitinib was observed.

In the fully adjusted Model 3, the CMI was significantly higher in both the Q2 group (β = 0.14, 95%CI: 0.05–0.22, P = .001) and the Q3 group (β = 0.19, 95%CI: 0.10–0.28, P <.001) compared to the Q1 group, with a significant trend observed ( P for trend <.001).

Recently, NPs have become a significant trend in drug delivery, particularly as nanotherapeutics, due to their ability to enhance the solubility, stability, and bioavailability of drugs.

The multivariate logistic model considered only variables with a significant trend in the single-split analysis.

Adjuvant chemotherapy has been a component of adjuvant therapeutic strategy for women with breast cancer owing to the observation that adjuvant chemotherapy yielded a significant trend toward the benefit for DFS and OS. 30 As compared with single-agent chemotherapy, significant progression-free survival (PFS) and OS benefits resulted from CMF polychemotherapy. 31 The incorporation of anthracycline agents and taxane including docetaxel and paclitaxel into adjuvant paradigm has been permitted for further improvements in spite of potential risk for increasing adverse effects. 30 , 32 However, the diverse effects of breast cancer subtypes were infrequently referred and discussed.

Intriguingly, while lower overall, the proportions of LCFAs showed a significant trend of being higher in XFZ compared to YSD in both TAG and polar lipids.

One study that specifically investigated tuning curve widths in macaque MT found a significant trend of narrowing tuning curves during visuomotor adaptation (Krekelberg et al., 2005 ).

There was a significant trend among tertiles of TyG index levels and risk of severe CSVD burden.

10 Similarly, in Ontario there has been a significant trend in the decline of children who have been administered various vaccines.

Emerging Trends and Challenges In recent years, there has been a significant trend in the development of stimuli-responsive cellulose-based materials.

Notably, Adipoq was primarily expressed in differentiated adipocytes, with a significant trend toward increased expression in the 16‐month‐old mice relative to the younger control (Figure 1f ).

In contrast, the lack of a significant trend in the clinical data suggests, or the absence of a corresponding QC shift suggests no meaningful loss of process control (end-of-process).

A significant trend of higher surface hardness was observed among herbivores followed by omnivores and carnivores ( Figure 1 A), and the mean surface hardness of the enamel in herbivores (p value <0.05) and omnivores was significantly higher than in carnivores ( Figure 1 B).

Regarding the SEER staging, the OCSS (P=0.017) and OS (P=0.004) of patients with distant stage showed a significant trend toward increased, while no significant trends were found in the survival of patients with localized or regional stage diseases.

For the EPA/AA ratio, participants in the highest quartile also showed a significantly lower odds of HTG those in the lowest quartile (AOR, 0.64; 95% CI, 0.46–0.88), despite the absence of a significant trend across quartiles ( P for trend = 0.179).

Also, across the increasing quartiles of RC showed a significant trend regardless of the adjustment models (All P for trend <0.05).