“a significant trend”

S4C), which inversely showed a significant trend toward hypermethylation in the majority of iCCAs when compared with normal controls, further proving the necessity of WGBS for an accurate evaluation of iCCA DNA methylation.

When analyzing the serum cytokine response, we did observe a significant trend toward Th2 cytokine production at 7 days post-bite.

Consistent with the retrospective study which suggested the event-free outcomes for patients with lower eGFR levels was significantly shortened ( 28 ), our results displayed significant difference regarding composite endpoint among different eGFR groups, whereas we saw a significant trend that patients with impaired kidney function in the dabigatran anticoagulant population might experience shorter event-free outcomes.

The reduction of lag of germination, meaning a significant trend for a faster initiation of germination with increasing temperatures was found in heat treatments below 100 °C.

Trend test (Z = −4.8656, P < 0.0001) indicates a significant trend in SPP by age group.

There was also a significant trend of increasing cumulative odds of 1-year mortality with a higher FI-Lab level ( P for trend < 0.001).

Interestingly, in the agency-specific analyses, UNT exhibited a significant trend that is opposite of the exhibited identification rate trends of White decedents twice as frequently identified as Hispanic decedents.

A spraying activity with surface liquids performed outdoors (close to buildings) showed a significant trend toward occupational exposure dominance in 81% of cases.

In contrast, there was a significant trend for increasing PIP IC 50 s in both Plasmodium species from 2010 onwards.

lowest duration category was 1.48 (95% CI 1.26–1.74; I 2 = 50.4%), with a significant trend across categories (P for trend = 0.03).

While no direct association emerged between parental age and offspring mortality, we identified a significant trend toward reduced mortality risk with increasing paternal age, particularly among offspring of non-educated parents (P for trend = 0.02).

We observed a significant trend of an association between IBD classification and the response to molecular-targeted therapy.

On the other hand, studies that were adjusted for broad groups of carcinogens (i.e., List A jobs or high risk jobs for lung cancer) did find a significant trend between level/duration of DME exposure and lung cancer [ 15 , 16 ].

How do patient demographics impact the acceptability of the visual function HM app? Regardless of the financial consequences, there was a significant trend towards in-person examinations due to age, education level, urbanicity, travel distance, and patients who never used telehealth before, as shown in Figure 1 .

We observed a significant trend for increasing age in the MetS+BP group.

These findings highlight a significant trend of high turnover among coordinators within their first 5 years.

In addition, the results of PLS-DA showed that the FM treatment group showed a significant trend of segregation on the principal component 1 axis (PC1, with 26.8% explained variance), which indicated that the structure of the intestinal flora of the FM treatment group differed from that of the other groups significantly.

In recent years, there has been a significant trend toward the use of 3D printing technology to fabricate soft material structures for soft robotic systems ( Gul et al., 2018 ).

Its integration into medical education and workflows is a significant trend in healthcare.

A significant trend was demonstrated for improved survival in patients with cancer located in the cecum towards the sigmoid colon.

After three hours after administration, Iopamidol-based MRI-CEST pH imaging showed a significant trend to more alkaline pH values in Esomeprazole-treated mice.

These observations indicate that there may not be a significant trend for switch-like exons to be formed by Alu elements, but switch-like exons are more likely to be surrounded with Alu elements in upstream and/or downstream introns.

Although all the transitioned patients had low disease activity as reflected by their DAS28 value, there was, nonetheless, a significant trend showing a relationship between disease activity and success in the transition.

The application of ML for spectrum analysis has emerged as a significant trend ( 13 , 14 ).

However, this study did not find a significant trend of consistent beliefs in all myths by either gender.