“a significant trend”

As the sum of mtDNA mutation VAFs increased, tumors showed a significant trend toward a higher immune-to-stromal (I/S) ratio ( p for trend = 0.013; Figures 5 A and S5 ), along with a corresponding increase in immune response gene set scores ( p for trend = 0.005; Figure 5 B).

Considering that the mean LOS was 2 days, the number of beds occupied by patients in the surgical group was 76 in a period of 6 months (13 beds per month). A significant trend in APACHE II score was detected in 181 (74%) out of 246 people, with the average score of 14.24±6.01.

In these studies, there was a significant trend for increases in the number of infections in contacts as the degree of smear positivity in index TB patients increased.

Similarly, a longitudinal analysis in healthy subjects has revealed a significant trend toward lower PRL concentrations with an increasing number of MetS components in women, although no association between PRL and MetS incidence has been shown in multivariable regression models ( 67 ).

We observed a significant trend in the expressions of rs1801028 genotypes when comparing the TRS group to the HCs group.

There was a significant trend towards a greater annual number of importations over the period.

On contrary to chlorophyll b, anthocyanin showed a significant trend of decrease in H and F, on the seventh day of heat treatment, it decreased 32% and 88%, respectively.

H&E staining revealed a significant trend toward higher inflammation scores ( P ​< 0.05; Figure 3 B).

There was a significant trend toward increased frequency of overall complications along with the severity of AKI (no AKI, 9.5%; stage 1, 31.6%; stage 2, 47.1%; stage 3, 60.0%; P trend < 0.001; Table 3 and Figure 1 ).

The result revealed that antiplatelet double therapy with clopidogrel plus aspirin was better than aspirin alone for reducing the risk of recurrent stroke and not increase the risk of bleeding among patients with high risk transient ischemic attack (TIA) or minor infarction 23) Due to our patient's acute hemorrhage on the frontal convexity, we were concerned the hemorrhagic transformation and rebleeding because dual antiplatelet therapy (clopidogrel plus aspirin) was associated with a significant trend to increase moderate bleeding. 17) So we treated with cilostazol plus aspirin successfully.

MLH1 expressing and non-expressing CFC show a significant trend towards greater CpG promoter methylation in CFC lacking detectable MLH1 expression.

found that there was a significant trend toward a higher re-operation rate after a PVP in men with larger prostates ( 15 ).

No other month of the year displayed a significant trend in either direction. 4.

For instance, we observed a significant trend for mutual exclusivity between truncal mutations in TP53 and truncal mutations in KRAS ( q < 0.001) and EGFR ( q = 0.031).

On the other hand, knowledge (variable 5 [Tau = − 0.163; p = 0.103]) and use of medicinal plants (variable 6 [Tau = − 0.184; p = 0.066]) did not reflect a significant trend.

A significant trend emerged from the comparative analysis of cpe -positive vs. cpe- negative strains: 80% (49/61) of cpe- negative strains carried 8 to 10 virulence genes, while 86% (69/80) of cpe -positive strains carried only five to seven virulence genes ( p < 0.05).

The prevalence of severe IVH in infants born at ≤ 24 weeks did not change over the study years 2007–2018 despite a significant trend for increased survival in this population.

There was a significant trend for immune biomarker levels according to the duration of smoking (≤5 years, >5 years), with the exception of MCP1 ( Table S5 ).

20 Research conducted using Demographic and Health Survey data from nine South and Southeast Asian countries, including Bangladesh, showed a significant trend toward surgical deliveries. 21 Asia recorded the highest average annual rate of CS increase, whereas the global average CS rate increased by 12.4% between 1990 and 2014. 20 In Bangladesh, the overall CS rate has increased significantly from 2.7% to 24% between 2000 and 2014. 21 , 22 The glo

Furthermore, a significant trend of increasing AL score was observed with the number of lifestyle factors (ORs = 1.16, 95%CI: 1.12, 1.20 per unit increase).

A significant trend of increasing missed injections was observed in both groups over the semesters ( Fig 3 , Tables II and III ).

More recently, a more detailed anatomical division of colon subsegments showed a significant trend in worse prognosis from the left- to the right-sided colon [ 19 ].

In fact, prior to the start of suitable cancer treatment, the patients who are diagnosed in an early stage of the disease showed a significant trend toward the overall survival rate and were offered a cost-effective means of cancer treatment, as compared to those diagnosed at a later stage [ 4 ].

Compared with children with no BD, those with mild and moderate or high BD had generally lower HRQoL scores across all domains, and a significant trend towards lower HRQoL scores with increasing BD levels was also found.

Introduction Creating nanostructures of bioreceptors (proteins, nucleic acids, cells, etc.) nowadays plays an important role in biosensing, and it constitutes a significant trend in advances in nanoscience and nanotechnology [ 1 , 2 ].