Patients classified as having severe malnutrition risk according to PNI criteria (PNI < 35) exhibited significantly higher risk of poor functional outcomes compared to those with normal nutritional status (PNI > 38) in the unadjusted model (OR = 3.78, 95% CI: 1.28–11.14, p = 0.016), with a significant trend across categories ( P for trend = 0.009).
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In children >2 years of age, there was a significant trend in increasing alpha diversity measures between children with CF not receiving CFTR modulators, children with CF receiving CFTR modulators, and healthy controls: OTUs 63.7 vs 74.7 vs 97.6, p < 0.001; Shannon 2.11 vs 2.34 vs 2.56, p < 0.001; inverse Simpson 5.78 vs 7.23 vs 7.96, p < 0.001.
After adjustment for confounders, compared with the lowest tertile of plant protein consumption, OR of incident CKD in the highest tertile was 0.29 (95% confidence interval [95% CI] 0.15 to 0.55) with a significant trend ( P for trend < 0.001).
Generally, introns harboring m 6 A modifications showed a significant trend towards more IR reduction compared to unmodified introns (Figure 4I ), indicating that modifications on retained introns may directly influence splicing efficiency. m6Aboost can be applied to predict m 6 A sites in human cells To test m6Aboost on miCLIP2 data from a different species, we performed miCLIP2 experiments with poly(A)+ RNA from human HEK293T cells ( n = 4 replicates with 30 million truncation events on average, Supplementary Figure S1F and G ).
Specifically, these texture-quantifiers followed a significant trend were SD, entropy and MPP were lowest, whilst mean intensity was highest for HCM followed by amyloid, AS and finally healthy controls.
There was a significant trend in the stepwise increase of risk for all-cause dementia, Alzheimer’s disease and vascular dementia in relation to the MetS component exposure score (each P for trend <0.0001).
We did not find a significant trend in this group, which may be due to the heterogeneous properties of their members.
We also found a significant trend for TYMP (rs11479) based on two observed homozygotes for the minor allele.
A significant trend for decreasing frequency of CC genotype with concomitant increasing frequency of allele T was demonstrated in tested groups categorized with accordance to GFR (controls – normal GFR, GFR category 1–3 ChGN patients – moderately decreased GFR, HD patients – severe GFR deterioration) ( Figure 1 ).
We also demonstrated a significant trend toward a decrease in mean values of isoenzymes of alkaline phosphatase, even though, also in this case, the mean values at 12- and 24-month observation were not significantly different.
The research indicated a significant trend towards decreased values in standing postural balance examination with eyes open up to 8 years of age, as the variation in the center of pressure decreased significantly with increasing age of the child.
The Mann–Kendall test on the fraction of useful reports shows p-values of 0.09, 0.09, 0.81, 0.22 for Barcelona, Valencia, Málaga, and Girona, which does not justify the presence of a significant trend in image quality, although any conclusions drawn from five data points must be handled with a pinch of salt.
observed a significant trend of decreasing BC odds with increasing soy consumption in a meta-analysis of eight studies conducted in Asian populations, who are major consumers of soy [ 9 ].
In the dot-clicking task, a significant trend was found in the number of clicked targets between the None and the RA conditions.
A significant trend was not observed when the investigators used unexposed participants as the referent group (OR = 1.0, 0.7, 0.9, 1.1, 1.6; p -value for trend = 0.15).
Thus, we can interpret these results as a significant trend in stone proportion increase with age, overall as also separately for males and females.
The emergence of a significant trend in any TC metric at the global scale is noteworthy because it is unclear whether natural climate variability can modulate TC behavior at this spatial scale.
A retrospective measurement of the CTQ was carried out to obtain a significant trend in the LOS.
Although some of the trials have been terminated because of limited efficacy and intolerable side effects, some have shown promising clinical results, such as a significant trend toward improved disease-free survival and tumor reduction with minimal side effects.
Pooled estimate analysis showed a significant trend toward smaller tumor sizes in LLR (mean difference − 0.26, 95% CI − 0.42 to − 0.10, p for effect < 0.001).
Introduction The increasing number of electric microvehicles in the form of Personal Light Electric Vehicles (PLEV), such as powered bicycles, several types of e-kick scooters and powered boards, represents a significant trend in contemporary urban mobility.
In the Polish army, BMI assessments between the year 2000 and 2010 revealed a significant trend for an increasing prevalence of overweight from 10.5% to 15.6%, and of obesity from 2.5% to 3.8%, respectively [ 6 ].
Null hypothesis is rejected and a significant trend exists in the time series if Z > Z 1 - α / 2 , in which Z 1 - α / 2 is obtained from the standard normal distribution table.
A significant trend toward a low muscle density with the increase in age was found for both sexes.
Trend analysis The Mann–Kendall (MK) test was carried out under the presumption that a significant trend is the one with a p value less than 0.05 (also represented by an absolute Z c score greater than 1.96) 42 , 43 .