Barely Significant
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“a significant trend”

9,775 sentences · 9,775 papers · 47,878 search hits before verification · confirmed specimen

Sighted at

p=0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

Patients classified as having severe malnutrition risk according to PNI criteria (PNI < 35) exhibited significantly higher risk of poor functional outcomes compared to those with normal nutritional status (PNI > 38) in the unadjusted model (OR = 3.78, 95% CI: 1.28–11.14, p = 0.016), with a significant trend across categories ( P for trend = 0.009).
In children >2 years of age, there was a significant trend in increasing alpha diversity measures between children with CF not receiving CFTR modulators, children with CF receiving CFTR modulators, and healthy controls: OTUs 63.7 vs 74.7 vs 97.6, p < 0.001; Shannon 2.11 vs 2.34 vs 2.56, p < 0.001; inverse Simpson 5.78 vs 7.23 vs 7.96, p < 0.001.
Generally, introns harboring m 6 A modifications showed a significant trend towards more IR reduction compared to unmodified introns (Figure 4I ), indicating that modifications on retained introns may directly influence splicing efficiency. m6Aboost can be applied to predict m 6 A sites in human cells To test m6Aboost on miCLIP2 data from a different species, we performed miCLIP2 experiments with poly(A)+ RNA from human HEK293T cells ( n = 4 replicates with 30 million truncation events on average, Supplementary Figure S1F and G ).
Although some of the trials have been terminated because of limited efficacy and intolerable side effects, some have shown promising clinical results, such as a significant trend toward improved disease-free survival and tumor reduction with minimal side effects.