“a significant trend”

For one other type (myeloid leukaemia), there was a significant trend in the former but not in the latter, and for two others (stomach and kidney), there were significant trends in the latter but not in the former.

For those miRNAs that showed a significant trend in a regression model, we presented the median values of relative expression of miRNAs (2 ΔCt ) in a bar plot per time interval and for controls.

However, this is a controversial issue, mainly because the presence of TgAb may not be useful in a significant proportion of patients due its low prevalence [ 14 ], and also because there is as yet no clear definition of the magnitude of TgAb level variation and the period of time over which it occurs that would be necessary for it to be regarded as a significant trend in their concentrations.

A significant trend for higher intake of carbohydrate was detected among cases compared to controls.

[ 35 ] found a significant trend across three time-points for fat mass and multisite pain, with the number of painful sites significantly associated with total body fat mass over 5 years.

Regarding the contribution of the seven selected SNPs and cancer risk, only rs6060627 in BCL2L1 showed suggestive association with overall cancer risk, with a significant trend when the analysis was focused on females ( P trend = 0.03) ( Table 5 ).

Conversely, for non-pregnant patients, a significant trend was observed in the overall number of hospitalizations overtime, with a mean increasing trend of +0.7% per year (95%CI: 0.2, 1.2).

The content determination results indicate a significant trend in the total content of DFA III and DFA I during the processing.

p -value < 0.05 was deemed to be significant, and 0.05 < p -value < 0.1 was deemed to show a significant trend.

This study was discontinued early by the independent ethics review panel because of a high number of serious adverse events and deaths in the placebo arm, and a significant trend toward improvement in PFS in the treatment group ( 58 ).

A significant trend involves constructing a “Quadruple-Helix” collaboration model spanning basic research, engineering, clinical validation, and industrialization.

P < 0.05 was considered indicative of a significant difference, whereas 0.05 ≤ P < 0.10 was considered indicative of a significant trend.

There was also a significant trend seen with increasing numbers of kissing partners in the last 3 months ( P trend = 0.029).

However, anti-inflammatory responses among cells do not lead to a significant trend of synchronization.

A value of −0.404 ( P -value <0.001), indicated a significant trend to show that the cancer progression is negatively correlated with DEC1 expression.

While this is a significant limitation, we addressed it analytically by performing a study-level meta-regression using oral corticosteroid prevalence, which revealed a significant trend, suggesting that higher oral corticosteroid exposure may amplify the ICS-associated risk.

A significant trend in thermodynamic solubility values with Ca/P ratio was found 20 , which limits the candidates usable in nearly neutral or slightly acidic conditions (such as those found in plant leaves and stems).

MFM demonstrated a significant trend of being most knowledgeable about cfDNA screening followed by OB/GYN, GP, and lastly MW in almost all aspects of cfDNA screening.

There was a significant trend for PDE5i/SGCS/ERA monotherapy and PCY-containing regimens among patients prescribed PAH therapy by cardiologists and pulmonologists.

A significant trend of genotype frequencies being associated with age can indicate a gene-longevity association.

Abstract Nurse exportation, driven by sociodemographic factors, has become a significant trend in many African countries, including Ghana.

We did not detect a significant trend over the study period or a step change or change in slope following the introduction of the first UK lockdown in age or AUDIT scores of new app users ( Table 4 ).

For male participants, nonresponse was significantly associated with mild psychological distress, whereas no significant association with severe psychological distress was noted although there was a significant trend for an increased risk of psychological distress among nonresponders ( P for trend = 0.0019).

Stratification by DI-GM categories revealed that participants with a score of ≥6 had a significantly lower likelihood of breast cancer (crude OR = 0.65, 95% CI: 0.54–0.85, p = 0.002; adjusted OR = 0.67, 95% CI: 0.45–0.89, p = 0.006), with a significant trend across increasing DI-GM levels (adjusted p for trend = 0.014).

There was a significant trend of decreasing QSM values in GPe and GPi across iRBD, PD non-RBD, and PD-RBD patients, which seems related to increasing motor severity measured with MDS-UPDRS-III (Supplementary Fig. 1 ).