Barely Significant
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“a significant trend”

9,775 sentences · 9,775 papers · 47,878 search hits before verification · confirmed specimen

Sighted at

p=0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

A previous study reported a significant trend between low DVS and low intakes of legumes, green-yellow vegetables, fruits, and eggs, and significant trends between lower intakes of energy, protein and fat and lower DVS. 17 In addition, the group with DVS ≤2 had a significantly higher odds ratio with frailty when referenced to groups with DVS ≥5. 17 It was also reported that a group with DVS ≤2 was significantly related to lower lean mass and grip strength in Japanese elderly. 14 We categorized DVS ≤2 as “low”.
( 18 ) Assuming that a higher dose results in increased efficacy, the power to detect a significant trend over the dose range (Cochran‐Armitage test of trend; α = 0.05) was tested in six scenarios, based on hypothesized efficacy, with chosen sample sizes pooled across Cohort 1 and Cohort 2: placebo: n = 10; palovarotene 5/2.5 mg: n = 9; palovarotene 10/5 mg: n = 21 (Table S 5 ).
While we did observe a significant trend for higher all-cause ( Figure 2A ) and cardiovascular mortality ( Figure 3A ) in patients in the lower T 50 -tertiles (i.e., increased calcification propensity) (p for trend = 0.036 and 0.04, respectively), there was no significant difference in overall all-cause or cardiovascular mortality between T 50 tertiles in log-rank analysis ( p = 0.068 and p = 0.101, respectively).