“a significant trend”

To assess whether these changes followed a significant trend along the EMT spectrum, we performed a regression analysis treating EMT state as an ordered variable, which revealed a significant decrease in the proportion of Gzmb+ CD8+ T cells ( P = 0.032) and a significant increase in the proportion of Tregs ( P = 0.044) along the EMT spectrum.

The results demonstrate a significant trend in evaluating the stability of the treatment methods and serve as guidance for further biomechanical and clinical studies.

Fasting glucose, TG, and TC levels were elevated across the groups ( p < 0.01), with a significant trend even after adjustment for age, but not after the correction of multiple testing.

This review highlighted a significant trend for toucans and the Guianan Cock-of-the-rock ( Rupicola rupicola , Linnaeus 1766) to consume and disperse smaller seeds.

For ordinal variables with significant associations with frailty, the Cochran‐Armitage test for trend was used to confirm a significant trend in the association with frailty for increasing ordinal level.

Her father was reported a significant trend in ADAS, AQ, PAS-SR, SHI-SHY and SHY-OBS scores.

A significant trend in mobile learning apps development involves gamification concepts that incorporates play and fun elements to inspire and attract the learner, generally referred to as serious games.

A real‐world study has also reported a significant trend for greater weight reduction with liraglutide in patients with higher baseline BMI. 25 In the present analyses with oral semaglutide, body weight reductions were seen across BMI subgroups, with a general pattern towards greater reductions in body weight in patients with higher baseline BMI within several of the PIONEER trials.

INTRODUCTION There is a great demand for healthy skin that is radiant without imperfections, and ‘glowing’ skin has become a significant trend with a demand that has gained momentum worldwide [ 1 , 2 , 3 ].

The SEN-Minus and Gamma-Minus architectures demonstrate a significant trend, which reduces total stage counts through the implementation of multiplexers (MUXs) and demultiplexers (DEMUXs) 9 , 11 .

An epidemiological study from 616 Italian non menopausal women exposed to the Seveso explosion found a significant trend for an earlier age at menopause in the four first quintiles of level of exposure to TCDD at the time of explosion but not for the 5 quintiles, suggesting a nonmonotonous dose-related effect [ 101 ].

15 For the base materials, the rise of nickel foam (NF) is a significant trend; this material quickly gained popularity since its introduction in 2010 20 and is the most popular base material in our collected studies.

In luminal A type disease, there was a significant trend toward shorter DFS and OS in the group with low ARID1A expression compared with the group with high ARID1A expression.

Trend analysis showed a significant trend toward decreased prevalence of MAFLD with increasing eGDR-related indices quartile (all P for trend <.01).

Our findings indicate that when HbA1c is treated as a categorical variable, there is a significant trend towards increased risk of poor functional outcome at 3 months with rising HbA1c levels.

We further observed a significant trend of decreased risk of obesity with increased SI intake in postmenopausal women but not in premenopausal women.

In the multivariate-adjusted model (model 3), HR estimates were 0.95 (0.82 to 1.10) for 1–2 times/week, 0.84 (0.72–0.97) for 3–6 times/week and 0.82 (0.69–0.98) for ≥7 times/week, respectively, exhibiting a significant trend ( p for trend < 0.01) between frequency of egg intake and the risk of mortality ( Table S1 ).

We were surprised to observe there was a significant trend for higher breast cancer incidence in patients exhibiting a large number of cardiovascular risk factors.

Subsequently, the antitumor effect of each group was evaluated by monitoring the tumor volume every 2 days over 16 days Figures 7B,D revealed that except for the PBS and IM groups, the other groups showed a significant trend of tumor shrinkage after treatment.

When analysed as quartiles, SHR showed a significant trend with increasing risk.

The mean length of stay of these hospitalizations was 8.9 days (SE, 0.06), and there was a significant trend towards increased length of stay over time ( P trend <0.001; Figure S3 : trends in mean length of stay over time).

A significant trend toward fewer vascular combined resections and more R0 resections was noted in the NAC-GS group.

Meta-analysis of four randomized controlled trials among 228 cases demonstrated a significant trend toward decrement of ALT and AST circulating concentrations in studies with ≥1000 mg daily CUR supplementation and in trials with 8-weeks intervention, respectively [ 51 ].

For the 108 remaining species, we removed those that had insufficient data to determine a significant trend, which we defined as a capture rate <5 individuals/year.

Conversely, the intake of preserved vegetables was positively associated with an increased risk of oral/pharyngeal and laryngeal cancers, with a significant trend observed for both ( 47 ).