“a significant trend”

When examining the hourly reimbursement rates for the most commonly performed sports procedures, there is a significant trend toward lower reimbursement for longer procedures even after accounting for complication rates.

To correct for possible sampling bias we also ran this analysis on a randomized “null” data set, with the expectation that if there were a significant trend in the actual data, the results would differ significantly from the null data.

However, “aa” genotype polymorphisms in ApaI SNP and “a” allele showed a significant trend towards a lower frequency among patients with CL compared to control indicating that this association could represent a protective effect against CL.

After accounting for potential confounders, we observed a significant trend across the tertiles of dietary intake for three DASH diet indices, Mellen’s, Fung’s and Günther’s, with P-trend values of 0.01, 0.002, and 0.03, respectively.

26 Hilty found clinical improvement for depression in both groups that received either telephone-based intensive disease management modules (IDMM) and televideo-based psychiatric consultation versus telephone-based disease management (DMM) alone with a significant trend favoring the IDMM group. 27 Medication Adherence In three papers, medication adherence was a reported outcome.

A statistical test ( p -value) was used only for results showing a significant trend, with alpha 0.05.

This method is primarily based on two parameters, S and Z , to determine whether a time series has a significant trend.

In patients without DM, compared with Q1, the fully adjusted ORs for 90-day unfavorable outcomes were 0.939 (95% CI 0.629–1.403) for Q2, 0.638 (95% CI 0.411–0.989) for Q3, and 0.596 (95% CI 0.368–0.964) for Q4, with a significant trend (P for trend = 0.011).

The indicator of a significant trend was the P -value of the regression coefficient (β for step length and c for step width).

A significant trend was observed between ABI and cognitive impairment ( P for trend = 0.031).

Targeted therapy with high CDK selectivity has become a significant trend.

This revealed a significant trend of below average stability for neural fate mRNAs and above average stability for localized mRNAs (Figure 4 A, Additional file 8 ).

The data analysis highlighted a significant trend in the increase of heat stress conditions (increase in THImax values) in the summer period 1991–2022, in Mugello areas, more evident in LM despite HM.

We observed a significant trend to lose the mucoid phenotype over time in the population, and this phenotype did not correlate with the antibiotic resistance profile of the isolates.

Downstream trade is more dispersed, with a significant trend towards multi-polarization.

In California, we also found a significant trend of northward and altitudinal expansion of areas suitable for C. capitata establishment.

When looking at Table 4 , however, some exceptions can be noticed: breast and prostate cancer showed no trend, consistent with the fact that they did not turn out to be associated to CRC as FPC; thyroid cancer also lacks a significant trend, likely due to the small number of cases included in the study; endometrial cancer was the only cancer type which showed to be at an increased risk with a constant trend in time.

Moreover, a significant trend toward shorter LOS over time was confirmed.

A significant trend of increasing psoriasis ASPR, ASIR and ASDR is observed in all SDI regions from 1990 to 2021.

This finding was also supported by unadjusted analyses of the individual segmentations, which revealed a significant trend toward an increase in the number and total volume of brain contusions with a worse outcome category (Table 3 ).

Slattery et al (2013) examined the dietary oxidative balance and observed a significant trend toward reduced breast cancer risk with a higher dietary oxidative balance. 18 Xu et al (2025) analyzed US cancer survivors and found that a higher OBS strongly predicted lower all-cause and cancer-specific mortality, 19 suggesting that even after diagnosis, better oxidative balance confers a survival advantage.

In the multivariate logistic regression analysis, the rs738409 GG or GC, and rs139051 TT genotypes were found to be associated with increased risk of NAFLD, and a significant trend of increased risk with increasing numbers of risk genotype was observed in the cumulative effect analysis of these single nucleotide polymorphisms.

DDT showed a significant trend for NHL risk with life-time days of use RR = 1.0 (ref), 1.3 (0.9–1.8), 1.1 (0.7–1.7), 1.7 (1.1–2.6); p trend = 0.02, while the intensity weighted lifetime days of use of DDT was of borderline significance: RR = 1.0 (ref), 1.2 (0.8–1.8), 1.1 (0.8–1.7), 1.6 (1.0–2.3); p trend = 0.06.

According to the logistic regression analysis, in unadjusted model, compared with participants without any elevated liver enzymes, the OR of diabetes was 1.47 (95% CI: 1.32–1.65) for participants with one elevated liver enzymes, 1.60 (95% CI: 1.36–1.89) for participants with two elevated liver enzymes, and 2.17 (95% CI: 1.69–2.79) for participants with three or four elevated liver enzymes, with a significant trend in OR with increasing number of elevated liver enzymes.

The innovation of exercise-centered lifestyle intervention therapy may become a significant trend in the future.