The RHODOS trial failed to show a benefit for its pre-specified primary end point (best recovery of visual acuity at week 24), but all of the secondary end points showed a positive trend towards visual improvement in the idebenone-treated group ( Klopstock et al., 2011 ).
The districts with the highest population density, the cities of Munich, Nurnberg, and Augsburg, had a negative trend in total mortality, while most of the remaining districts had a positive trend, mirroring quite likely the concentration of the mobile, younger working population where the jobs are.
The meta-analysis, though statistically insignificant, suggested a positive trend favoring enalapril's effect on rCBF [ 28 , 31 ].
Moreover, there was a positive trend with increasing age in non-HPV-16/18 CIN3 patients [ 41 ].
Starting from 7 May 2017, a positive trend characterizes a new regime where the number of cryptocurrencies grows slightly in a gradual and regular fashion.
Generally, when keeping the other properties of NPs such as surface charge constant, their hydrophobicity has a positive trend with their cytotoxicity. 74 Muthukumarasamyvel et al. 81 controlled the hydrophobicity of dicationic amphiphile-stabilized AuNPs by conjugating the dicationic functionality with different numbers and locations of H and OH groups.
In both datasets, CXCL8 expression was negatively correlated with T.cells.CD8 ( Figure 8C,D ), whereas CXCL8 showed a positive trend of correlation with T.cells.gamma.delta ( Figure 8E,F ).
A positive trend in vaccination rates was observed, especially in Venice historical centre.
Similar to the findings in CP/CPPS patients, elevated levels of IL-1α, IL-1β, IL-4, IL-13, and TNF-α were observed in CP/CPPS rat prostates, and these elevated cytokine levels showed a positive trend in their correlation with anxiety, depression, and memory impairment.
A follow up period by 4th April indicated increased case fatality among Blacks/AA, 3.3%, resulting in a positive trend in case fatality with respect to period change 22.2%.
From 1980 to 2000, PISCOt v1.2 showed similar variability (a slightly positive trend) to ERA5-Land, then moves closer (a slightly negative trend) to PISCOt v1.1 and VS2018 in the 2000–2007 period, and finally, since 2010, being in agreement with PISCOt v1.1 and VS2018 and ERA5-Land into a positive trend.
Large nationwide registries indicate that up to 60% of patients with sepsis are over 65, with a positive trend for diagnosis of 1.5% per year [ 3 ], with particular relevance in subjects ≥80 years [ 2 ].
On the other hand, ribulose, phenylalanine, aspartate, thymine, hypoxanthine, and glycylisoleucine levels showed a positive trend with PA, with highest levels in the high PA group.
lEVs isolated from the patients’ bloodstream (cEV) and the supernatant of the primary sEV culture showed a positive trend on xenograft volume.
Main findings All studies, except for one sub-study showed a positive trend in the relationship between prenatal antibiotics and childhood asthma, of which the majority were significant, ranging from OR 1.13 (1.02-1.24) to OR 3.19 (1.52- 6.67).
A positive trend was also observed for the <3‐month and >3‐ to 6‐month follow‐ups (Table 2 ).
While the perceived sense of similarity or affinity was moderate (mean 3.46, SD 0.94), it still indicated a positive trend in user closeness.
Our analysis revealed a positive trend in the field of aquaponics, which is illustrated in Figure 3 .
This reduction likely results from enhanced public health initiatives, increased awareness of tobacco’s health risks, and stricter regulations, reflecting a positive trend in reducing tobacco consumption.
There was a positive trend, low variability, and positive immediate and pronounced change.
61 , 62 The adoption of these advanced analytical techniques in Africa indicates a positive trend toward the development of environmental monitoring and research capabilities.
Concomitantly with the resolution phase of the injury response (2–12 weeks), Prg4 levels returned to a baseline and showed a positive trend in association with the recovery of typical SMC markers.
Thermal performance results showed a positive trend, PET’s hydrophobic nature reduced water absorption by 20% and chloride ingress, making it suitable for humid/marine environments despite higher porosity. iv.
Both δ 2 H and δ 18 O values had a general trend of increase from 5 to 207 cm of depth, then a drop of values at 227 cm, and again a positive trend up to 427.5 cm, followed by a negative trend down to the bottom of the core, at 567.5 cm.
[ 43 ] In relation to histopathological variables, we have also observed an association between NHL development with the density and monoclonality of lymphocytic infiltrations as well as a positive trend towards germinal center formation.