“a positive trend”

Creatine monohydrate administration has a positive trend in the survival of ALS patients with no adverse events 43 .

In addition, there is a positive trend in increase of ALP level, animal weigh, and normalization of ADA activity that can indicate an improvement of kidney state.

Although there was a positive trend this was not significant due to the presence of an outlier who was the only patient with an ILAE outcome of Class V in this group ( Fig. 4 ).

There was a positive trend in life expectancy over the years, with 2018 having the lowest and 2019 the highest life expectancy during 2015–19.

In the completed phase I and II trials in ALS patients ( ClinicalTrials.gov Identifier: NCT01091142 , NCT01281631 ), NP001 was found to be safe, well tolerated, and presented a positive trend in slowing disease progression ( 120 , 121 ).

Moreover, the implementation of join-point regression analysis, also known as change-point regression or segmented regression analysis [ 33 ] to detect changing trends in cancer incidence (see for example [ 34 , 35 , 36 , 37 , 38 , 39 ]) further confirms that the incidence rate in Romania presents two join points in 2014 and 2017, leading to three periods with a different trend over the analysis period, as follows: a positive trend with a slope coefficient of 14.68 until 2014, a negative trend with a slope coefficient of −8.83 during 2014–2017, and a slightly increasing trend with a slope of 2.05 after 2017 ( Figure 4 , Panel b).

At the same time, a positive trend in equipment, infrastructure, and staff qualifications is evident.

Although both the AMBASSADOR and CheckMate 274 trials reported a benefit in DFS, only CheckMate 274 demonstrated a positive trend in OS based on Kaplan–Meier curves, as the necessary follow-up duration to assess long-term outcomes has not yet been reached [ 26 ].

A negative trend indicates success whereas a positive trend indicates failure.

In particular, they also found a positive trend of RAtR aggregated over the European region in the E-OBS dataset from 1950 to 2020.

(2019) found no additional effect on gait speed in the subacute phase but a positive trend in the chronic phase.

In this context, the present findings may be interpreted as a positive trend.

Among the 11 analyses that met all three MR assumptions, 4 demonstrated a significant causal difference between BMI and keratoconus, while the remaining 7 showed a positive trend but were not statistically significant.

Histopathological quality The histopathological R0-resection of malignancies showed a positive trend, although without statistical significance as shown in Table 3 .

Predictive Value of IP-10 (IP-10, CXCL10) The current study showed that baseline values of IP-10 showed a positive trend toward the rapid progression in CRC patients during CTH.

One-study-removed analysis indicated that this study did not change the overall results, but it did contribute to a positive trend for the ciNPT-MLA group when included.

We could find a very similar trend in the VERTIS-CV trial, where despite not meeting the primary endpoint (MACE), the exploratory endpoint of CV death had a positive trend compared to DECLARE TIMI-58 and CANVAS program.

This led to the observation of a positive trend in adsorption capacity.

This is a positive trend with more studies focusing on the Hong Kong context in terms of PA among children.

There may have been a positive trend in the direction of greater human capital as the proportion of men and women at round 4 studying was higher, if not statistically significant.

4 Results The incidence of CHE declined across all thresholds throughout the study period, reflecting a positive trend (see Table 3 ).

The rates of condom use (male and female) at last sex show a positive trend in many regions with some Latin American and European countries reporting rates among 15 to 24 year olds of more than 80%, although lower increase of around 30% have been recorded in some African countries. 4 In particular, condom use at last higher-risk sex has increased over the past 3 decades in most countries across the world and is as high as 80%–90% in some countries. 17 DVR vaginal rings do not protect against STIs and pregnancy and if introduced into a population with high rates of condom use at last high-risk sex, it would be important to support the use of both methods.

Low rates of change in occupancy might indicate a positive trend in the site occupation of species within this protected area.

Figure 2 , lower panel, displays the sizer plot with the transition between the colors blue and purple indicating a change in the trajectory of behavior from a negative trend to a zero trend, and colors transitioning from purple to red, changes in behavior from a zero trend to a positive trend ( Chaudhuri and Marron, 1999 ).

The number of scans also affected the resulting final surface coverage, although with a much more limited impact, showing a positive trend with the increase in the number of scans.