“a numerical trend”

During follow-up, however, we noticed a numerical trend toward improved performance with tele-rehabilitation with VAPA compared to traditional rehabilitation, though it was not statistically significant.

There was a numerical trend that cfABCB1 tx levels at primary diagnosis were elevated in platinum resistant patients (ED = 304 mRNA copies/20 μl serum).

The percentage of sputum lymphocytes were significantly lower in COPD patients compared to HNS ( p = 0.011), while there was a numerical trend for higher neutrophil percentages in COPD patients and HS (versus HNS) and higher eosinophil percentages in COPD.

The SpaceOAR RCT showed statistically significant improvements in bowel QOL up to 3 years, whereas the Barrigel RCT showed a numerical trend toward improved bowel QOL at 3 to 6 months, but this was not statistically significant.

While a numerical trend suggested better survival with daily amphotericin compared to alternate-day dosing, the difference was not statistically significant in this cohort; conversely, statistically significant associations between treatment schedule and disability were observed, possibly reflecting complex interactions among dosing, cumulative exposure, supportive care and selection bias (sicker patients may have received alternate dosing) ( 5 , 8 , 9 ).

Nevertheless, Experiment 2 revealed a numerical trend towards such an effect, thereby warranting a more elaborate discussion.

Although all studies which reported TLF demonstrated a numerical trend towards a reduction in TLF, the finding was driven predominantly by one study (BIOFLOW V).

Conclusion Higher EGFR VAF was significantly associated with improved overall survival in patients with EGFR-mutated NSCLC treated with first-line osimertinib and showed a numerical trend toward longer progression-free survival.

This was also observed among patients with T2D [ n = 304] (− 31.9 mg/dL at 1 year, P < 0.0001); there was a numerical trend towards reduced FPG in patients with T1D [ n = 14], but this was not significant (− 36.7 mg/dL at 1 year, P > 0.05 [Supplementary Material Fig.

Despite a numerical trend, statistical significance was not confirmed for Lp(a) levels in relation to MADS2-CVD or MADS2-PVD scores.

35 Proprotein convertase subtilisin/kexin type 9 inhibition reduces the composite end point of cardiovascular death, MI, stroke, hospitalization for unstable angina, or coronary revascularization in patients with stage G2 CKD (60–90 ml/min per 1.73 m 2 ), with a numerical trend for benefit in late-stage CKD. 36 Overall, patients with late-stage CKD or ESKD are under-represented in clinical trials; as such, the current evidence base to support recommendations is limited. 35 Invasive Management and Revascularization The efficacy of OMT alone or in combination with revascularization (PCI or coronary artery bypass grafting [CABG]) in symptomatic patients with CKD or ESKD remains unclear.

At later time points, weeks 52, 65 and 78, the treatment effect persisted as a numerical trend in favor of pridopidine.

Over 26 weeks, switching to IDegAsp from glargine U100 or U300 was associated with significant reductions in the daily total and basal insulin dose; furthermore, numerically fewer patients required prandial insulin injections at EOS compared with baseline, with a numerical trend toward a lower daily prandial insulin dose after initiating IDegAsp.

In stratified analyses, patients with wider baseline QRS duration and female sex showed a numerical trend toward greater benefit with the AP strategy, although these findings did not reach statistical significance and should be interpreted cautiously.

We also observed enrichment of the peroxisome-proliferator-activated receptor alpha (PPARα) signaling pathway, along with a numerical trend of decreased AT levels of OEA and PEA, which are known to activate PPARα 68 .

A numerical trend toward a higher proportion of patients without radiographic progression in mTSS (SDC criteria) was observed at Years 1 and 2 in favor of the no-GC subgroup.

A direct comparison of P1 and P2 revealed a numerical trend toward superiority of the combined treatment for Version 1 and a significant add-on effect for Version 2.

Physiological stress and hematological responses White blood cell counts showed a numerical trend, with T3 exhibiting the lowest and T1 the highest values, though the differences were not statistically significant.

There was a numerical trend for early separation between the spesolimab and placebo groups during the first week, favoring the spesolimab group.

A numerical trend toward higher complications, particularly major bleeding (11.4% vs. 3.4%), was observed in the half-dose group, although not statistically significant.

Although there was a numerical trend in the predicted direction, which did not differ substantially between learning conditions (Fig. 4b ; Supplementary Fig. 5 ), we found no direct effect of signed image RPEs on memory ( ps ≥ 0.19; α corrected = 0.0125; Supplementary Table 12 ).

Vitamins and Minerals There was no statistically significant difference in micronutrient intake of vitamins between the two groups, with all details shown in Table 2 , although there was a numerical trend towards higher intake of vitamins D and K among the PC patients.

Most comparative studies evaluating two‐row versus three‐row circular staplers have reported either lower anastomotic leakage rates or a numerical trend favouring three‐row devices [ 4 , 5 , 8 , 10 ], although these findings have varied according to study design and methods of confounding adjustment.

A further correlation also demonstrated this trend in relation to fecal calprotectin as an objective measure of IBD activity; however, this was only observed as a numerical trend without reaching statistical significance.

History of prior HZ showed a numerical trend towards increased incidence among patients who developed HZ in the present cohort, but significance was similarly unmet.