Another retrospective analysis from NCDB including 2187 patients with pT3/4 or LN-positive variant histology disease, failed to demonstrate an OS benefit of adjuvant chemotherapy in patients with non-pure UC, although a numerical trend towards improved survival was seen in neuroendocrine tumors and micropapillary differentiation [ 65 ].
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In some instances, there was not even a numerical trend favoring the age-matched children with typical language development.
A numerical trend toward an increase in integrated density in the RD-CFA compared to RD SAL was also observed ( Fig. 4B ).
10.1136/jitc-2020-000871.supp1 Supplementary data Discussion Our study did not observe a significant difference in overall toxicity between age cohorts, although there was a numerical trend toward lower all-grade and ≥G3 toxicities in the ≥75 years compared with the younger cohort, and the discontinuation rates for toxicity were lowest in the oldest age cohort.
This resulted in a numerical trend in favor of ribociclib in TTD ≥10% in global HRQOL (HR = 0.81 [95% CI, 0.62–1.1]).
ISR incidence decreased over time regardless of BMI group or dosing regimen, with a numerical trend toward fewer ISRs in the higher BMI group overall ( Figure 1 ).
TSST, which overlaps to some extent with PFS2, showed a numerical trend favoring atezolizumab-containing therapy in the ITT population (Fig 4 A).
The biomarker studies in MORPHEUS-PDAC showed a numerical trend toward increased OS and improved HR for OS with atezolizumab plus PEGPH20 vs. control in HA-positive patients.
Baseline characteristics The mean age showed a numerical trend toward lower values in the ORIF group, although the difference was not statistically significant ( p = 0.162).
The left atrial level of Gja5 mRNA transcripts was significantly reduced, and there was a numerical trend to decreased expression of Gja1 in the atrial AMPK-dKO mice ( Figure 5A ).
When patients were categorized by weight change (weight loss > 1 kg, weight stable, weight gain > 1 kg), there was a numerical trend towards a greater increase in energy intake in those who had gained weight, but this did not reach statistical significance [ 21 ].
For other endpoints, the differences between the treatment groups at week 24 were mostly not statistically significant and/or small, but with a numerical trend towards superiority of the add-on strategy.
In contrast, the LC group showed no significant survival benefit with higher cytarabine doses, despite a numerical trend toward better RFS in the ID subgroup (84.0% vs. 63.6–71.1%).
3.7 Clinical Subtypes and Clinical Severity Correlation PSP‐RS showed a numerical trend to greater impairment in all measures, compared to the non‐Richardson syndrome variants, however, none of these differences survived FDR correction for multiple comparisons (Table S7 ).
Of note, KCCQ‐12 score significantly improved from preoperatively ( P < .001); however, although there was a numerical trend toward improvement in post‐procedural 6‐minute walk tests, the results were not statistically significant (Table 6 ). 4 DISCUSSION The MV apparatus is a very complex structure with multiple different architectural and dynamic facets that incorporates compliance, preload, and afterload to determine its successful function.
However, there is a numerical trend suggesting a slightly higher occurrence of DE in the perioperative period in the Amulet group compared to Watchman group.
Even though the analysis of the PrC BA 36 did not reveal any significant effects, there was a numerical trend consistent with the PrC BA 35 results (see Fig. 2 D).
In exploratory multivariate analysis, Pembrolizumab treatment showed a numerical trend toward improved survival compared to other PD-1 inhibitors.
[ 20 ], we did not find a significant difference in the CVD event rates across former and never smokers, although there was a numerical trend in the same direction as the findings in the study by Joseph et al.
30 In our study of mostly European, HBV genotype A/D, long-term virologically suppressed, HBeAg-negative patients, we observed no association between EOT anti-HBc IgG levels and “milder” HBV DNA relapse, a numerical trend with biochemical flares of any type and, for the first time, demonstrated that severity of off-treatment virologic relapse and biochemical flare is significantly associated with low EOT anti-HBc IgG levels and low but detectable HBcrAg levels.
Although no significant differences were observed in HHF, a numerical trend favoured eplerenone.
A numerical trend was seen for higher albumin levels at vedolizumab LOR among patients undergoing subsequent medical (median 4.1, IQR 3.9–4.4 g/dl) compared to subsequent surgical therapy (median 3.9, IQR 3.17–4.1 g/dl, p = 0.24).
We found a numerical trend toward a higher s-IFX concentration in children on azathioprine, but without reaching statistical significance, probably due to the small number [ 4 , 10 ].
Although not significant, there was a numerical trend toward bilinguals responding more slowly than other groups (particularly, musicians and bilingual musicians).
Although a numerical trend favored revascularization, the differences were not statistically significant in most pooled analyses, and the authors concluded that contemporary OMT may constitute a viable alternative to revascularization in selected low-risk symptomatic patients ( Rodrigues et al., 2025 ).