Results Adolescents who attended education sessions had significant and clinically relevant improvements in asthma control (ACQ score difference: −0.6; P =.03) and exhibited a nonsignificant trend of improvement in asthma-related quality of life (Pediatric Asthma Quality of Life Questionnaire score difference: −0.45; P =.15) when compared to those who did not adhere to education.
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Accordingly, in the univariable competing risk regression model (Table S2 , Figure 1A ), ever‐smokers showed a nonsignificant trend toward a higher risk of de novo HCC when compared to never‐smokers (subdistribution hazard ratio [SHR]: 2.27; 95% confidence interval [CI]: 0.75–6.89; p = 0.150).
We found a nonsignificant trend that JAK1 frameshift and nonsense mutations were more frequent in subjects without clinical benefit (33% vs. 7%; P = 0.15; two-sided Fisher exact test; Supplementary Fig.
Beta-blockers showed a nonsignificant trend toward benefit (HR: 1.7, p = 0.15), while RAAS inhibitors and MRA had no significant impact. 4 Discussion The study assessed the recovery of left ventricular ejection fraction (LVEF) in patients with heart failure with reduced ejection fraction (HFrEF) of non-ischemic aetiology.
Preincubation with β-glucan prior incubation with C48/80 resulted in a nonsignificant trend, P = 0.15, of lower release of β-hexosaminidase compared to cells stimulated with C48/80 only ( Fig. 7A ).
In the scanner, a positive correlation was observed between COMT val allele load and performance (number of correct responses) for the spatial high g f task; r = 0.47, P < 0.03 2 tailed, with a nonsignificant trend in the same direction for the verbal high g f task; r = 0.31, P = 0.15 2 tailed.
However, the prognostic effect was only significant in the validation set ( P = 0.015; it showed a nonsignificant trend in the training set of ABC-DLBCL, P = 0.15), and the number of cases with long K/LCDR3 length was small (4 and 3 in the training and validation sets, respectively).
Only a nonsignificant trend for reduced volume was detected for hippocampus (9.06% for Fus + /+ vs. 8.62% for Fus ΔNLS/+ ; p = 0.15; Two-sided Unpaired Student’s t -test) and striatum (9.76% for Fus + /+ vs. 9.89% for Fus ΔNLS/+ ; p = 0.56, Two-sided Unpaired Student’s t -test).
Overall survival There was a nonsignificant trend toward improved OS in the tivantinib group (19.8 months; 95% CI, 13.4–27.0) compared with the placebo group (16.9 months; 95% CI, 12.2–20.4; HR, 0.70; P = 0.15) (Fig. 2 b ).
Detectable VL at 24 weeks showed a nonsignificant trend toward OT failure (OR = 3.25, P = .15); however, this became statistically significant when the VL cutoff was increased to 1000 copies/mL (OT failure: OR = 8.33, P = .04).
In the maternal pituitary, KiSS-1 mRNA expression exhibited a nonsignificant trend ( p = 0.15) toward lower expression in T (0.42 ± 0.61) relative to relative to C (1.76 ± 0.58) animals.
A nonsignificant trend for the biomarker effect was also observed in both treatment groups in the adjusted analyses (alectinib HR = 1.95; 95% CI, 0.78–4.83; P = 0.1506; and crizotinib HR = 1.52; 95% CI, 0.88–2.63; P = 0.1323).
There was a nonsignificant trend in rates of complete occlusion between fusiform/dissecting (91.7%) and saccular aneurysms (70%; P = 0.151).
28.0%; p = 0.025), with a nonsignificant trend toward higher diabetes prevalence (59.2% vs. 48.8%; p = 0.152).
Crtc1 −/− male mice had increased levels of Agmat protein in the HIP ( t =−2.72, df=6, P =0.036), whereas a nonsignificant trend ( t =−1.51, df=9, P =0.152) of increased Agmat was observed in the PFC ( Figure 1d ).
A nonsignificant trend for lesser use of mechanical ventilation (26.5% vs. 22.1%, P = 0.152) and vasopressor support (20.5% vs. 15.9%, P = 0.304) was observed during the second wave but mortality at 60 days from admission (24.5%) was in the range of what was previously reported, 31 , 32 with no significant difference between the first and second wave ( Figure 4 a; Log rank test, P = 0.48).
There was also a nonsignificant trend for CC carriers to have higher pre-morbid IQ ( P = 0.152).
median 61 minutes, IQR 55–129 minutes, P = 0.006) and a nonsignificant trend towards longer total CPB time (median 185 minutes, IQR 178–210 minutes vs. median 149 minutes, IQR 99–195 minutes, P = 0.152).
Additionally, a nonsignificant trend towards higher PAI-1 levels was found in metastatic disease ( P = 0.153) ( Figure 3(h) ), whereas the uPA levels showed no significant differences between localized and metastatic disease ( Figure 3(g) ).
There was a nonsignificant trend toward a faster time to discharge with DPP (4.6 days vs 7.01 days in the FOE group; P = .154).
A nonsignificant trend toward improved OS (19.3 vs. 16.2 months; p = 0.155) and PFS (8.1 vs. 5.05 months; p = 0.143) was observed for patients with left-sided versus right-sided primary tumors (Supplementary Fig. 1 ).
Statistical trend analysis revealed a nonsignificant trend towards increasing clinical pregnancy loss rates with longer IPIs ( P = 0.156).
In the case of the light chain, there was a nonsignificant trend over time where LV1 and LV7 usage increased and decreased over time, respectively (Supplementary figure 4g ) (LV1: P = 0.1563, LV7: P = 0.250), whereas LV2 and LV3 showed a significant increase and decrease, respectively, in their gene usage overtime (LV2: P = 0.0313, LV3: P = 0.0156).
There was a nonsignificant trend toward association in interpreter need mischaracterizations and patients who were listed as Hispanic/Latinx in the EMR (χ 2 (1, N = 156) = 1.9915, p = 0.1582).
Hypertension showed a nonsignificant trend toward higher prevalence among participants with DR (60.4% vs. 49.8%; p = 0.160).