Hypertension showed a nonsignificant trend toward higher prevalence among participants with DR (60.4% vs. 49.8%; p = 0.160).
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Among STE-based indices, RVFWS global showed a nonsignificant trend toward increased risk (HR: 1.19; P = 0.16).
24.5%) with a nonsignificant trend towards improved OS (HR 0.44, p = 0.16) [ 35 ].
Compared with those who declined assistance, patients who received educational counseling had significantly lower odds of readmission (aOR, 0.53; 95% CI, 0.31–0.90; P = .02), and those who were initiated on addiction-related medications showed a nonsignificant trend toward reduced risk (aOR, 0.62; 95% CI, 0.32–1.21; P = .16).
Sensitivity analyses demonstrated that there were no effects on all‐cause mortality across subgroups based on age, sex, or ethnicity (Figures S8 through S10 ), although there was a nonsignificant trend to increased mortality among the White population with RASi therapy (RR, 1.52; [95% CI, 0.85–2.72]; P =0.16).
The median ST in the moderate and high risk groups was 6 and 3 months, respectively, showing a nonsignificant trend of shorter survival in the high risk group ( P = 0.16).
For visual disturbances and blindness, we observed a nonsignificant trend toward risk reduction at 3 months (RR 0.588, 95% CI 0.276–1.254, p = 0.163) and 24 months (RR 0.788, 95% CI 0.490–1.268, p = 0.324).
VGCV showed a nonsignificant trend toward less frequent use in ARM‐positive patients (36% vs. 65%; p = 0.163).
When comparing varyingly attained lowest LDL-C levels, a nonsignificant trend toward alower HR of CV and all-cause mortality was noted at the LDL-C level between 70 and 100 mg/dL (CV mortality; HR: 0.64; 95% CI: 0.35–1.20; p =0.164; all-cause mortality; HR: 0.84; 95% CI: 0.65–1.08; p =0.177). 4.
As shown in Figure 2 , one-way ANOVA followed by Newman–Keuls post-hoc tests revealed no significant difference in the level of c-Fos ( F (2,13) = 2.409; P = 0.1288) among the three age groups, and a nonsignificant trend toward a decrease in Zif268 with age ( F (2,14) = 2.055; P = 0.1650).
SGLT2i use was associated with significantly fewer HF exacerbations (HR 0.64, 95% CI 0.48–0.86; p < 0.01), all-cause hospitalizations (HR 0.72, 95% CI 0.58–0.91; p < 0.01), and acute kidney injury (HR 0.53, 95% CI 0.35–0.79; p < 0.01), with a nonsignificant trend toward lower all-cause mortality (HR 0.83, 95% CI 0.63–1.08; p = 0.165) [ 45 ].
In univariable analysis, induction chemotherapy plus ICI showed a nonsignificant trend toward improved PFS compared with chemotherapy alone (HR, 0.43; 95% CI, 0.13 to 1.42; P = .165).
For switch trials, the effect of TMS showed significance when stimulating the rIFG in TW2 ( t = −2.98, P = 0.003) and TW5 ( t = −2.38, P = 0.018), with marginal significance in TW4 ( t = −1.76, P = 0.078) and a nonsignificant trend in TW1 ( t = −1.39, P = 0.166).
When regarding CDT, PPA reduction after treatment, distal IENFD, and pain induced by capsaicin individually, there was a nonsignificant trend towards more patients with the combination of capsaicin-induced pain and reduced distal IENFD in the responder group (4/7 vs 0/2; Table 6 , χ 2 test, P = 0.167).
Consistent with the accuracy data, the reaction time data also showed a nonsignificant trend towards a word-meaning priming effect (all primed conditions vs. unprimed: β = –0.060, SE = 0.043, z = –1.379, p = .168), and there was no evidence of an expectedness effect ( p s > .724). 2.2.1.3 Rate of correct responses (RCR) As an exploratory analysis, we combined the accuracy and reaction time data to form a measure of the rate of correct responses (RCR) a participant makes in this task, defined as the (proportion of correct responses/((RT in ms/60,000)) (see Vandierendonck, 2017 , for an evaluation of this method).
There was a nonsignificant trend for a more extreme inverse association with higher amounts of daily cigarette consumption ( χ 2 = 1.90; P = 0.168; Fig. 1 ).
A nonsignificant trend toward a higher prevalence of an abnormal microcirculation in the highest lactate quartile was observed ( P = 0.169) (Fig. 1 ).
There was a nonsignificant trend toward treatment difference observed in the high-dose IV cohort of 0.024 (95% CI –0.011 to 0.060; unadjusted p = 0.169) for SUVR BAI-WM , representing a 30% reduction in amyloid accumulation relative to placebo (Fig. 2e ).
FIGHT (Functional impact of GLP-1 for heart failure treatment in patient with advanced heart failure) study ( N = 300) conducted with liraglutide (Median left ventricular ejection fraction of 25%) had a nonsignificant trend of increase in HHF (HR = 1.30, 95% CI 0.89-1.88, P = 0.17) and death (HR = 1.10, 95% CI, 0.57-2.14, P = 0.78).[ 28 ] Another study LIVE (Liraglutide on Left Ventricular Function in Chronic Heart Failure Patients With and Without Type 2 Diabetes Mellitus) also found a significant increase in serious adverse cardiac events with liraglutide (12 vs. 3, P = 0.04), compared to placebo.[ 29 ] Forest plot in Figure 6 summarizes the HHF outcomes in all CVOTs.
However, the pooled results were stable except for the female group, as only a nonsignificant trend of higher contralateral reinjury rate (RR, 1.34 [95% CI, 0.88-2.06]; P = .17) was shown when including the studies with a high risk of bias.
There was a nonsignificant trend toward a decrease in the cell frequency of the AT2 A subcluster with CS ( Supplemental Figure 2B , P = 0.17).
Bivariate correlation analyses, using Pearson’s correlation coefficients for baseline expressions of the aforementioned genes with the clinical parameters, revealed a negative correlation between PKM2 gene expression and the ΔDAS28 after 3 months of follow-up (r = −0.433, p = 0.02) and only a nonsignificant trend with regard to SDHB expression (r= −0.274, p = 0.17).
There is also a nonsignificant trend when only considering the nine mixotrophs ( r = −0.5, p = 0.17).
During the study period, there was a nonsignificant trend toward fewer deaths (secondary endpoint) in the CSP group compared to the CP group (25% vs 37%; HR 0.71, 95% CI 0.43–1.15, P = .17).
Across all TCGA breast cancer cases, enrichment of the murine AGED signature showed a nonsignificant trend toward shorter PFS (HR = 1.3, 95% CI = 0.9–1.8; p = 0.17; n = 1109) (Fig. 7C ), that became significantly associated with worse PFS among women age ≥65 years at breast cancer diagnosis (HR = 1.9, 95% CI = 1.0–3.6; p = 0.036; n = 323) (Fig. 7D ).