“a nonsignificant trend”

While heterogeneity remained high ( I 2=88.1%, P <.001), the 95% PI and the borderline significant P value support that eHealth interventions provide a nonsignificant trend for depressive symptoms.

Likewise, the minor allele of SNP rs3803662 in the TNRC9 locus also showed a nonsignificant trend with a larger number of first-degree relatives with breast cancer (on average, 0.23 in major allele homozygous patients versus 0.28 and 0.31 for heterozygous patients and minor allele homozygous patients, respectively).

In this experiment, once again, the effect was compound-specific, with significantly higher susceptibility to CEES for pme-2 , parg-2 , and sirt-2.1 mutants ( Figure 7 a), whereas upon HN2 treatment, only parg-2 survival was significantly reduced, while pme-2 and sirt-2.1 showed a nonsignificant trend ( Figure 7 b).

The quality of evidence was very low because bias, inconsistency and imprecision in the several considered studies; however, the meta-analysis reported a nonsignificant trend towards improved waitlist survival and post-transplant outcomes for patients undergoing bridge therapies.

Among female participants with the Hp2‐2 phenotype, having low HDL‐C compared with non‐low HDL‐C was associated with a nonsignificant trend toward a lower CAD risk (HR, 0.54 [95% CI, 0.28–1.07], P interaction for sex=0.03).

Again, similarly with profibrotic changes, there was a nonsignificant trend toward a high-glucose-independent increase in proinflammatory mediators MCP-1 and TNF-α in animals receiving saline and dapagliflozin ( Figure 5 B). 5.6.

A nonsignificant trend to improved memory was seen in the NORT for the 5xFAD mice at 5 mg/mL CAW.

There was also a nonsignificant trend of a higher rate of HBeAg positivity among male participants, although no evidence of a sex difference in HBV DNA concentrations exists.

On the high-fat diet, however, MI4KO mice demonstrated significantly impaired insulin tolerance and mildly reduced glucose tolerance overall, with a nonsignificant trend toward elevated evoked insulin during the GTT ( Fig. 4 I – K ).

In a nonsignificant trend, the T2D+P+anti‐LCN‐2 group showed TNF‐α levels that were 2.29 times lower than those in the T2D+P+IgG group (Figure 5A ).

There was also a nonsignificant trend towards longer OS if the onset of the irAE was more than 3 months after starting ICI therapy. 86 Another study again noted improvement in ORR, DCR, median PFS, and median OS in patients who developed an irAE on ICIs.

On the contrary, a nonsignificant trend of increased risk of pneumonia was observed in NGF group.

A nonsignificant trend toward a decrease was found upon LPS exposure ( S6C ii Fig ).

Two independent statistical groups evaluated 37 prespecified baseline and postrandomization factors from the PLATO trial and found a significant interaction between treatment and region ( P = 0.045), with North American participants (US and Canada) demonstrating a nonsignificant trend towards an unfavorable treatment effect with ticagrelor for the primary endpoint (HR 1.25; 95% CI 0.93–1.67) compared to a favorable outcome in the other regions combined. 32 , 20 Out of the baseline and postrandomization factors, the dose of aspirin taken concomitantly with ticagrelor was the only accounting factor found to explain the geographic differences observed in the PLATO trial.

One day before survey completion, a significant association is observed in the student survey cohort with the quantitative BDI-9 SI score (interaction β=.026, SD 0.011; F 4,54 =1.93, P =.02), while a nonsignificant trend in the same direction is observed on this day for the COVID-19 survey cohort with the quantitative QIDS-SR score (interaction β=.0017, SD 0.001; F 4,353 =3.49, P =.09; Table S1 in Multimedia Appendix 1 ).

They further showed a nonsignificant trend toward a reduced rate of brain injury progression in those receiving VTE prophylaxis.

Although we found substantial relationships between illness and specific political beliefs such as trust in Trump and confidence in the federal government, we observed only a nonsignificant trend associating self-reported political conservatism with a greater likelihood of having tested positively for COVID-19.

For instance, a single‐center study found only a nonsignificant trend toward higher readmission rates among obese PPCM patients, likely due to insufficient statistical power [ 11 , 16 ].

There was no change in response to vibration treatment in indolyl glucosinolates (vibration treatment p = 0.71), although there was a nonsignificant trend for an interaction of leaf type and vibration treatment (Electronic Supplementary Material Table 2), and the changes in some individual indolyl compounds mirrored those for aliphatic compounds (Electronic Supplementary Material Fig. 3).

Patients with an elevated lactate at presentation (>2.2 mmol L –1 ) had significantly higher rifampicin C max (median = 9.0 vs 6.5 μg mL –1 ; P = .002) and AUC 0–8 (median = 47.3 vs 36.7 mg h L –1 ; P = .006; Table 4 ) with a nonsignificant trend towards higher isoniazid and pyrazinamide C max and AUC 0–8 (Table 4 ).

There was a nonsignificant trend to prolonged brush-induced after-sensations in cases.

Additionally, a supplementary analysis using a clinically relevant AAC threshold (>6) yielded consistent results, with higher muscle strength showing a significant inverse association with severe AAC in males and a nonsignificant trend in females (Supplementary Table 2).

Combination treatment Anti‐DKK1 + ASCs showed a significant reduction in residual defect span, while either cell therapy or anti‐DKK1 alone showed a nonsignificant trend toward reduction in defect span (Figure 2B ).

Expression of NPFR RNAi in the P1 neuron caused a nonsignificant trend toward reduced water seeking in the P1 neuron ( Fig. 5 B’ ).

Changes In HVPG In the evaluable population (n = 22 with baseline and day 28 HVPG values), there was a nonsignificant trend for the HVPG to decrease after 28 days of emricasan (mean [SD] change from baseline of –1.1 [4.6] mm Hg).