Interestingly, baseline PC eigengene level did not show a significant correlation with longitudinal changes in skin thickness (MRSS), an endpoint that TCZ treatment failed to significantly impact in both the clinical trials, although there was a nonsignificant trend for a baseline correlation between PC score and MRSS.
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In covariate analysis ( Table 5 ), a nonsignificant trend toward an association between decreased serum calcium and severity of renal impairment was observed.
coli appeared to provide an intermediate transcriptional signature, with significant upregulation of Ctla4 , Pdcd1 , Cd274 , Havcr2 , Lag3 , and Klrc1 with a nonsignificant trend for Vsir .
Analysis of ultrasound energy metrics showed that FLACS was associated with significantly shorter effective phacoemulsification time (EPT) and a nonsignificant trend toward lower ultrasound time (UT).
Interestingly, these observations were not in line with a similar regulation of circulating miR-143 in our large collective of ICU patients, since miR-143 showed only a nonsignificant trend towards lower levels in critically ill patients compared to controls.
There was a nonsignificant trend toward reduced pain severity and fewer neuropathic pain symptoms in the intervention group after 18 months; however, this group also reported lower quality of life at trial completion.
Thus, at day 28, the Kids and PregMom groups exhibited increases of IL-10, 27.91% ( p = 0.0166) and 27.67% ( p = 0.0057), respectively, versus a nonsignificant trend of 33.68% decrease in the Placebo (Fig. 3e ).
Results first showed a nonsignificant trend for reduced median spindle count and density among the OSA group versus controls.
At 22 days, only a nonsignificant trend remained ( Fig. 6C ).
The results of the further control experiment analyzing the effects 3 h after the laser exposure did show a nonsignificant trend for higher threshold values.
Effectiveness of hibiscus on BP Our meta-analysis indicated that hibiscus significantly lowered SBP ( − 7.92% from baseline) and showed a nonsignificant trend to lower DBP ( − 6.84% from baseline).
Like mulch alone, mulch + workers elicited significant attraction at all doses (1×: t = 3.24, df = 9, p = 0.01; 2×: t = 4.21, df = 9, p = 0.002; 3×: t = 10.67, df = 9, p < 0.001) and only a nonsignificant trend for the dose effect ( Figure 4 c).
For the majority of other CD4 + and CD8 + T cells at least a nonsignificant trend toward higher values in MSI-H patients could be seen in the multivariate analysis.
Similarly, statistical significance was not achieved for PFS or ORR (Figure 4 A,B; Table 2 ); however, there was a nonsignificant trend toward improved PFS in the ruxolitinib group compared with the placebo group in substudy 2 (Figure 4 B).
When cytology results were compared according to the presence or absence of bacterial STIs (Table 2 ), no statistically significant differences were observed, although a nonsignificant trend toward a higher frequency of ASCUS cytology was noted among patients with STIs (17 vs. 13.2%).
Compared to men who hardly ever walked or biked, walking or bicycling an average of 30 min day −1 was associated with a nonsignificant trend for a 5% reduction in cancer incidence.
Consistent with the interpretation that our study had insufficient statistical power for detecting retention effects, the measures we used to assess the maintenance of behavior change consistently showed a nonsignificant trend in favor of optimized gamification (Figures S1 and S2 in Multimedia Appendix 3 ).
Although Kaplan–Meier and competing risk analyses suggested a nonsignificant trend toward slightly higher local recurrence with SS, this was offset by more competing events (non-cancer death, distant metastasis) in the MS group.
In our study, an infection control intervention in 2014 may have resulted in a decrease in PICC insertion, followed by a nonsignificant trend of PICC-related CRBSI reduction.
However, there was a nonsignificant trend, indicating that more patients who received the QR code consented compared to those who did not receive the QR code.
As Figure 2 shows, the university hospitals and the cancer center were associated with a significant, upward trend in DOT per 1000 PD and DASC per 1000 PD and a nonsignificant trend towards increasing DASC/DOT whereas the community hospitals were associated with a downward trend of all three parameters.
A nonsignificant trend toward reduction in the longest all-cause mortality was observed in the EGDT group compared with control care (relative risk, 0.89; 99% confidence interval, 0.74–1.07; P = 0.10).
11 – 13 We observed a nonsignificant trend toward a deeper ablation and consequently thinner residual stromal bed with WFG-LASIK.
A nonsignificant trend in OS was noted between mBAP1 and WT-BAP1 patients in cohort A (Fig 4 B).
In terms of the time participants spent in the same room with the virtual agents, we observed a nonsignificant trend suggesting that individuals with high social anxiety tended to favor spending time in the room with the friendly virtual agent (Experiment 1).