“a nonsignificant trend”

Effects on Alirocumab (Pharmacokinetics) When comparing alirocumab plus ezetimibe versus alirocumab plus placebo, total alirocumab C max values did not differ statistically (mean [SD] C max , 21.9 [8.9] versus 24.3 [8.6] mg/L; point estimate: 0.92 [90% CI 0.78–1.09]), with a nonsignificant trend toward lower AUC D57–85 in the alirocumab plus ezetimibe treatment group (364 [143] versus 445 [189] mg·day/L; point estimate: 0.85 [0.70–1.03]), suggesting slightly faster clearance of alirocumab in this group.

Urine microalbumin There was a nonsignificant trend for lower albuminuria levels in the NNRTI group (10.75 SEM + 4.45) compared to the INSTI group (102.92 SEM + 68.05, Fig. 5 ).

For the combination of MOC31PE and cisplatin, there was a nonsignificant trend towards reduced viability.

A nonsignificant trend in respondents reportedly exercising five or more times per week for 30 minutes or more.

Interestingly, we also observed SD induced increases in immobility time and a nonsignificant trend towards reduced distance traveled.

Peripheral happy targets showed evidence of a nonsignificant trend for a right-side advantage when embedded in crowds, t <1, but did show a significant advantage when presented peripherally on their own (M = 30 ms, SD = 129 ms) t (55) = 1.72, p one-tailed = .046.

However, a decreased risk of development of several types of cancer in patients treated with these therapies was observed in one study, 14 while another investigation found a nonsignificant trend of elevated risk of nonbreast cancers. 4 Intramuscular IFNβ-1a (Avonex ® ; Biogen Idec, Weston, MA) is a first-line disease-modifying therapy administered weekly for treatment of relapsing forms of MS.

One cohort study reported a nonsignificant trend of increased cancer mortality in association with elevated NLR 17 .

When the specific types of stroke were analyzed separately, left ventricular mass was significantly associated with ischemic stroke in both sexes and with hemorrhagic stroke in men, with a nonsignificant trend in women ( Table 2 ).

However, we did observe a nonsignificant trend toward poorer survival for non-primary OLT and for female patients (see Appendix Supplementary Materials 5).

We found a nonsignificant trend for O 2 consumption by AT to decrease with increasing obesity.

33 A retrospective analysis of 979 patients in the QUASAR (Quick And Simple And Reliable) trial (majority stage II) revealed a nonsignificant trend toward increased chemotherapy efficacy with increased bud counts, 34 which is consistent with our study, that is, although time to recurrence was similar in BD1 tumors, adjuvant chemotherapy with UFT for 1 year seemed to be associated with an improved 5-year recurrence rate by approximately 5% in both BD2 and BD3 tumors.

We also note that NMTM patients at baseline revealed a nonsignificant trend toward more severe HF parameters (lower LVEF and higher NT‐proBNP), which may explain persistent differences seen at follow‐up.

41 While no clear association was found between DIDO and admission NIHSS or mRS, there was a nonsignificant trend toward higher NIHSS and mRS at discharge and at 90 days with increasing DIDO times.

For the “snus up to 34 weeks” group, there was a nonsignificant trend of decreased birthweight.

Surprisingly, neutrophil depletion did not prevent LPS induced preterm birth, but actually resulted in a nonsignificant trend toward even earlier delivery.

Nevertheless, after adjusting for factors such as gender, multivariate analysis did not show significant difference in burnout between different HCW roles, although there was a nonsignificant trend toward higher exhaustion scores among nurses that has been observed in other studies. 48 Surprisingly, HCWs in administrative roles and those who work from home had relatively high disengagement scores, which may be linked to increased operational demands while switching to a different working environment at home.

Evaluation of retinas at P19 revealed that dexamethasone led to a nonsignificant trend in decrease of Tnf , Il6 , and Ccl2 ( Fig. 1 M ) accompanied by a decrease in IBA1-positive inflammatory phagocytes both inside and outside of neovascular tufts ( Fig. 1 N ).

There was also a nonsignificant trend for a shorter mean duration for the development of hypothyroidism in the drug-naïve patients.

There were no other significant differences in baseline characteristics between the clusters, though there was a nonsignificant trend toward lower CSF WBC among the hypoinflammatory cluster ( Supplementary Table 3 ).

found only a nonsignificant trend for positive nodes to be larger than negative ones [ 2 ].

The majority had obtained this information through media and there was a nonsignificant trend suggesting that patients with previous knowledge of DBS were more positive to undergoing such treatment.

However, linear regression including male-dominant studies revealed significant decreases in average and inferior RNFL thicknesses with longer ethambutol administration periods, and the decreases in nasal, superior, and temporal RNFL showed a nonsignificant trend.

Results indicated the assembly of heteromeric GlyRs in the cytoplasm for WT and mutant receptors with a nonsignificant trend indicating a possible increased affinity of the GlyR β A455P subunit toward GlyR α 1 in comparison to the WT receptor ( Fig.

230 Post hoc analyses of efficacy in morphological subtypes of AML among patients participating in the HDC/IL‐2 phase III trial, showed a nonsignificant trend toward improvement of LFS in those patients with M0/M1 (undifferentiated/minimal maturation) AML versus controls.