Barely Significant
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“a nonsignificant trend”

5,407 sentences · 5,407 papers · 7,516 search hits before verification · confirmed specimen

Sighted at

p<0.1

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

Both these trials were prematurely closed because of slow accrual; however, the pooled analysis of these trials showed a nonsignificant trend toward better OS in patients receiving adjuvant therapy. 4 , 11 On the other hand, the EORTC (European Organization for Research and Treatment of Cancer) 40983 trial did not find any survival benefit after a median follow-up of 8.5 years in patients treated with perioperative FOLFOX4 compared with
The Selenium and Vitamin E Cancer Prevention Trial (SELECT), testing the effects of selenomethionine (SMet, 200 μg/day) and/or Vitamin E in preventing prostate cancer was curtailed as it became apparent Se supplementation did not appear beneficial in the prevention of prostate cancer, and a nonsignificant trend towards T2D in the experimental group was reported [ 13 , 14 ].
Furthermore, findings for nonobese and physically active survivors showed either a nonsignificant trend or significantly lower fatigue scores of a medium effect size (0.28–0.54), apart from 1 study that reported slightly increased fatigue in nonobese subjects (0.04 [−0.33 to 0.41]). 30 Finally, pain was lower in the nonobese groups, with the difference between the nonobese and the obese groups rangin
The intervention group showed a nonsignificant trend toward being more likely to report 0% or 100% consistency of condom use compared to the control group (OR 2.25, 95% CrI 0.84-6.36), and of those, a nonsignificant trend toward being more likely to report 100% condom use consistency compared to the control group (OR 8.03, 95% CrI 0.22-330.31).
This study also reported significantly lower complication rates in IVIg- versus TPE-treated patients, 17 which was observed as a nonsignificant trend in two other trials. 12 , 18 Specifically, Diener et al. 12 observed comparable rates of clinical AEs, but lower rates of treatment-related AEs with IVIg than TPE treatment.
Of these, 5 reported a significant beneficial effect of 5 different probiotics 33 , 49 , 55 , 82 , 96 (1 of which 33 also showed no significant effect in another study 50 ), 15 (examining 11 different probiotics) reported no significant effect 30 , 36 , 37 , 50 , 57 , 59 , 60 , 61 , 66 , 80 , 83 , 88 , 93 , 94 , 95 (of which 1 reported a nonsignificant trend in favour of probiotics vs placebo), 95 and another reported a negative effect of the specific probiotic treatment. 64 Of the 21 studies, 9 had been published since the original consensus.