Finally, the uptake efficiency declined for both cell types scored with 8 or more Hoechst-positive foci, with a nonsignificant trend pointing to decreased efferocytosis in cKO cells, with 5.4 ± 1% of control cells, but only 2.8 ± 1% of cKO cells (Figure 2 C).
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There was a nonsignificant trend towards diagnosis of depression in the DSH group.
While the data did not detect any significant differences in VAS pain scale and physical function scale (PCS) data between the medication and nonmedication groups, there was a nonsignificant trend for higher PCS values in the nonmedication group, which may be a function of the difference in the number of patients in the groups.
The D:A:D study did not find a significantly increased risk of cardiovascular events with ATV [ 29 , 41 ], and the Centers for AIDS Research Network of Integrated Clinical Systems cohort found a nonsignificant trend toward a reduced risk of atherosclerotic events with ATV compared with other protease inhibitors (hazard ratio 0.78; 95% CI: 0.42–1.45) [ 52 ].
SA-β-gal activity was also quantified via histochemical staining of the lungs and a moderate reduction in the senescence marker was observed for compound 98 , whereas 25 and ABT-263 showed a nonsignificant trend ( Figure B, bottom panels).
Prebiotics showed a nonsignificant trend toward reducing depression.
Increases in secretion of the inflammatory cytokines IL-6, IL-8 and IFN γ were observed, together with a nonsignificant trend for IL-12p40 and TNF α , in LAK/DC co-cultures compared with LAKs and/or DCs alone.
A nonsignificant trend toward impaired PE contraction was observed in all other groups.
Comparisons between results, stratified by examination times, exhibited a nonsignificant trend toward increased positivity at prolonged incubation times.
Bupropion showed a nonsignificant trend towards improved scores on cognitive tests compared to nondrug users.
We did find an elevated risk of cLEE with use of NNRTIs (driven by EFV, RPV) and TDF, a decreased risk of cLEE with DRV/b use, and a nonsignificant trend toward decreased risk of cLEE with TAF.
Variants showing a nonsignificant trend for association in more than one dataset included rs10931697 for TP53 GOF in the EUR validation, AFR validation, and MyBrCa studies ( P values 0.008, 0.02, and 0.09, respectively), and rs6709393 ( P values 0.003 and 0.16) in the MyBrCa and B-CAUSE studies.
In the L341V group, there was a nonsignificant trend toward a decrease in number of photoconverted SQSTM1‐bodies from the “after” to the first period (Figure 4E and Figure S7D ).
Relaxation velocity was significantly increased in hECT transfected with hsa-miR-548v as compared with hECT transfected with miRNA negative control ( Supplemental Figure 3F ), while there was a nonsignificant trend for a higher developed force in hECT transfected with hsa-miR-548v ( Supplemental Figure 3G ).
The direction of the effect suggested a nonsignificant trend toward lower MD among adolescents with a prior attempt, but the wide confidence interval (Exp[B] = 0.307, 95% CI = 0.001–65.405) indicated substantial uncertainty and instability in this estimate.
A nonsignificant trend toward increased serious adverse events or treatment discontinuation was observed (odds ratio = 1.52; 95% CI: 0.66; 3.50), with low heterogeneity.
Mortality results were modified (RR 0.92, 95% CI 0.83–1.02, p = 0.098), with a nonsignificant trend of lower mortality rates in patients randomized to SSD.
A larger sample size is needed to reliably assess the effect of metreleptin therapy on mortality risk in the GL subgroup, where a nonsignificant trend towards lower mortality was observed, as well as in subgroups of specific GL and PL subtypes.
10 , 12 , 29 However, we did find a nonsignificant trend of 1.7‐fold higher enhancement ratio in recurrent stroke patients than that in stable patients at follow‐up MRI.
Another observational study found that replacing saturated fat with low glycemic index carbohydrates was associated with a nonsignificant trend toward lower risk of myocardial infarction, while replacement of saturated fat with high glycemic index carbohydrates was associated with significantly higher risk (hazard ratio: 1.33; 95% CI: 1.08, 1.64) [ 37 ].
Of note, this growth factor was not affected by the NSAID type (treatment effect) and time effect, although carprofen showed a nonsignificant trend of higher values at 6 h ( Figure 2 B).
There was a nonsignificant trend towards a greater rate of first time attendance to ANC in intervention C compared to controls ( Table 2 ).
There was also a nonsignificant trend for a positive correlation between the AAAQ inclined/indulgent subcale (weak “approach”) and the SRC task approach bias score.
Two-sided Fisher exact testing revealed no statistically significant difference in detection rates between grade 3 versus grade 4 ( P = .421) or grade 2 versus grade 3 ( P = 1.000), with a nonsignificant trend toward lower detection in grade 4 relative to grades 2/3 combined.
Higher team scores on neuroticism showed a nonsignificant trend toward more aggressive behavior, OR 1.23 (95% CrI 0.90–1.53).